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Hot topics in Neurology and Psychiatry > Neuro-infection > Flashcards

Neuro-infection Flashcards

1
Q

CNS

A

brain and spinal cord

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2
Q

PNS

A

neurons in fingers etc

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3
Q

infections in lining of the brain

A

meningitis

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4
Q

infections of the brain parenchyma

A

(werkzame deel van het weefsel) enncephalitis, abcess

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5
Q

infections of spinal cord

A

myelitis

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6
Q

infections of peripheral nerve

A

neuritis

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7
Q

infections of nerve roots

A

radiculitis

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8
Q

infections of muscle

A

myositis

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9
Q

is bacterial meningitis acute or chronic?

A

acute

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10
Q

is lyme disease acute or chronic?

A

chronic

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11
Q

neck stiffness is a complaint of the infection..

A

meningitis

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12
Q

what are symptoms of meningits

A

nausea, vomiting, muscle pain, headache, neck stiffness, fever, confusion, sensitivity to light, cold hands or feet and mottled skin, rash.

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13
Q

hoe measure je meningitis

A

via CSF

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14
Q

what is the treatment for meningitis

A

IV fluids (altijd goed), IV antibiotics because oral cannot pass the BBB. You also want to give immunosuppressants.

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15
Q

wat is meningitis in het nederlands

A

meningokokken

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16
Q

waar is de vaccinatie PCV voor

A

streptococcus pneumoniae

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17
Q

waar ga je naar kijken in volgorde bij iemand met zulke klachten?

A
  1. medial history
  2. physical examination
  3. blood culture, markers of inflammation
  4. lumbar pucture
  5. CSF analysis
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18
Q

meeste mensen hebben 2/4 criteria van de volgende symptomen..

A

headache
fever
impaired consciousness
neck stiffness

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19
Q

welke zijn de 3 meest voorkomende

A

FIN

fever
impaired consciousness
neck stiffness

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20
Q

wat zie je aan de blood markers

A

leukocyte count is elevated

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21
Q

wanneer mag je geen lumbar puncture doen?

A
  • disorders of coagulations (DIS, anti-coagulants)
  • patients die septic zijn
  • cerebral lesion that causes brain shift -> kans op cerebral herniation
  • seizure
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22
Q

kan je bepalen via medical history of het bacterial of viral is?

A

nee, extra tests voor nodig.

23
Q

wat kan je doen om te kijken of een lumbar punction mag?

A

CT scan als patients:

  • neurological decifits
  • score on glasgow coma state <10
  • immunodeficiency
  • new onset of epileptic seizures at presentation
24
Q

CSF analysis

A

bij BM patients ziet het er cloudy en yellow uit.

  • meer dan 2000 leukocytes
  • meer dan 2 gram proteine
  • minder dan 1,9 mmol aan glucose (want bacterien verbruiken glucose)
25
Q

bij een systemic infection is..

A

de leukocyte count never elevated!

26
Q

pneumonal meningitis is caused by … bacteria

A

streptococcus

27
Q

verschil viral and bacterial meningitis in CSF

A

in BM all abnormalities are a bit more extreme: more leukocytes, more protein and less glucose

28
Q

treatment in neonatal

A

amoxilicine + cefotaxim/gentamycine

29
Q

treatment in children

A

ceftriaxon

30
Q

treatment in adults

A

ceftriaxon/cefotaxim

31
Q

bij resistent pneumococcus

A

add vancomycin

32
Q

dextamethason in..

A

all patients that have suspected BM

33
Q

maar niet bij …

A

listeria monocytogenes

34
Q

common outcomes of BM

A

stroke, epilepsy, hearing loss and shock

35
Q

start treatment within

A

1 hour after presentation!!!

dextamethason within 4 hours

36
Q

hoe meer complement factor 5 de patienten hebben, hoe

A

worse their outcome is

37
Q

macrophage migration inhibitory factor

A

biomarker voor BM, elevated in BM

38
Q

severity ligt aan..

A

de host

39
Q

en susceptibility ligt aan

A

het pathogen

40
Q

radial is over het kortste/langste deel

A

kortste

41
Q

tangenial is over het

A

langste deel

42
Q

neurological complaints of covid

A

headache, anosia (niet ruiken) en ageusia (niet proeven)

43
Q

associated diseases with covid

A

encephalopathie
cerebrovascular diseases
inflammatory cns and pns syndromes
stroke (hartinfarct)

44
Q

encephalopathy

A

changes in cognition, behaviour, personality or consciousness. het is geen infectie!

45
Q

stroke treatment

A

anticoagulation

46
Q

Guillian Barre syndrom

A

acute inflammatory polyradiculopathy -> demyelination in PNS. dit kan je ook zien in covid.

47
Q

acute disseminated encephalomyelitis

A

demyelation in CNS after infection

48
Q

what is encephalitis

A

inflammation of the brain parenchyma

49
Q

symptoms of long covid

A

headache, memory loss, vertigo, agnosia, insomnia, ageusia

50
Q

what is a complication of systemic coagulopathy in covid 19

A

ischemic stroke

51
Q

zijn post infectious inflammatory cns/pns syndromes rare?

A

ja

52
Q

is het direct invasion of the cns?

A

nee

53
Q

encephalopathy means

A

disease of the brain, without mentioning what cause

Hot topics in Neurology and Psychiatry (50 decks)

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