Magneencephalopathy

Question 1

MS lesions waar?

Answer 1

• periventricular
• juxtacortical
• infratentorial
• spinal cord

Question 2

symptoms of MS

Answer 2

• motor decifits
• ataxia
• sensory decifits
• autonomic dysfunction
• cognitive impairment

Question 3

discrepancy

Answer 3

symptom severity gaan niet hand in hand met aantal lesions

Question 4

waar kijk je naar in de imaging

Answer 4

gray and white matter lesions and atrophy

Question 5

what does magneencephalopathy measure

Answer 5

the magnetic fields induced by superfical neuronal sources

Question 6

generally the magnetic fields induced by….

Answer 6

post-synaptic neurons from pyramidal neurons

Question 7

MEG output

Answer 7

je zoekt naar spikes/spike waves. daarom doe je dit ook in mensen die wakker zijn, mensen die slapen hebben dan al extra slow waves.

Question 8

EEG vs MEG

Answer 8

• MEG better spatial resolution because it is not distorted as much by the schalp and hair as EEG
• EEG has a better specificity for more brain areas, because it can detect tangential and radial components of the signal. MEG can only detect tangential components -> therefore only sulci.

Question 9

wat is tangential

Answer 9

parallel aan de skull

Question 10

and radial

Answer 10

perpendicular (loodrecht) op de skull

Question 11

het signaal moet… zijn en …

Answer 11

langzaam (zodat er summatie is) en dicht bij (less sensitive for deeper sources)

Question 12

Alpha band … Hz is shifted to the … in MS patients (slowing of activity)

Answer 12

8-13, left

Question 13

short recap of waves

Answer 13

• beta bij concentratie,
• alpha bij closed eyes,
• delta is sleep,
• theta is children and sleep

Question 14

lagged phase synchronization

Answer 14

dezelfde wave maar later waardoor het niet gelijk loopt.

Question 15

amplitute correlation

Answer 15

wel gelijk