MS symptoms Flashcards
definition of MS
multiple scars in central nervous system
waar is damage?
grey and white matter, axons and neurons
er is loss of … en increase in …
tissue, fluids
stats over ms
meer female, start tussen 20-40 jaar.
symptoms
visual disturbances muscle spasms mental changes in concentration depression paranoia uncontrollable laughter limb weakness bladder and bowel dysfunction loss of sensation visual disturbances cognitive dysfunction pain tremor fatigue sexual function walking ability employment
common symptoms relapsing remitting MS
optic neuritis, sensory symptoms
optic neuritis
door inflammation of the optic nerve -> pain in eye movements and loss of vision in een oog, en loss of color.
common symptoms primary progressive MS
motor symptoms, walking disability
verschillende subtypes van MS
relapsing remitting ms
primary progressive ms
secondary progressive ms
progressive relapsing ms (rare!)
myeline is found in..
white and grey matter. hierdoor dus ook pathologie in grey matter, maar minder aanwezig.
life expectancy van ms
je overlijdt meestal niet van de MS zelf, maar van de symptomen (hoesten lukt niet meer)
juxtacortical
adjacent to the cortex
hoe kan je een nieuwe lesion zien?
door middel van contrast met T1. je spuit Gadolinium in en dit laat BBB breakdown zien, dus de inflammatory phase of lesion development.
wat is nodig voor MS diagnose?
dissemination in space and in time.
wat betekent dissseminaton in space and time?
This means showing that damage has occurred at different dates (DIT) and to different parts (DIS) of the central nervous system.