Neoplasia Part-2 Flashcards

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1
Q

Molecular carcinogenesis cellular genes name ? 4 type ..

A
  1. Growth promoting proto oncogenes
  2. Growth inhibiting tumor suppressor genes
  3. Genes that regulate apoptosis
  4. Genes involved in DNA repair

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2
Q

Cellular & Molecular hallmarks of cancer ??

A
  1. Sef sufficiency in growth signals
  2. Insensitivity to growth inhibiting signals
  3. Altered cellular metabolism
  4. Evasion of apoptosis
  5. Limitless replicative potential (Immortality)
  6. Sustained angiogenesis
  7. Ability to invade & metastasize
  8. Ability to evade the host immune response

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