Gastrointestinal System - Small & Large Intestine Flashcards

1
Q

Inflammatory Bowel Disease defination ?

A

Chronic condition
resulting from
complex interactions between intestinal microbiota & host immunity
in a genetically pre-disposed individuals t
that leads to
inappropriate mucosal immune activation

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2
Q

Crohn d site ?

A

any area of GI tract

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3
Q

Ulcerative colitis site ?

A

colon
rectum

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4
Q

specific sites of crohns disease >

A

terminal ileum
ileocecal valve
cecum

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5
Q

Crohn disease extent ?

A

transmura;

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6
Q

Ulcerative colitis extent >

A

mucosa & sub-mucosa

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7
Q

regional enteritis which one <

A

crohns disease

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8
Q

what is skip lesion?

A

sharply delineated areas in crohns d
179

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9
Q

macro of crohns D ?

A

179

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10
Q

distribution of CD

179

A

multiple
separate
skip lesions

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11
Q

wall of CD ?

A

All layer - inflamamtion
stricture - fistula - adhesions

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12
Q

narrow lumen X ray seen ?

A

String sign

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13
Q

mucosa of lumen feartures ?

A

serpiginous ulcer
= aphthous ulcer

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14
Q

mesenteric fat of macro ?

A

creeping fat

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15
Q

intervening surviving mucosa appearance >

A

cobblestone appearance

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16
Q

hallmark of crohns D >

A

non-caseating granuloma

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17
Q

Micro features of CD ?

A

179

transmural infiltration
patchy ulceration
epithelial metaplasia
loss of crypt epithelium

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18
Q

carcinoid tumor sites ?

A

appendix
terminal ileum
colon
rectum
lung
stomach
gall bladder
meckels diverticulum

182

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19
Q

Acute appendicitis etiology >

A

small stone like mass of stool = fecalith
gall stone
worms - oxyuriasis vermicularis
any tumor in the opening of appendix - benign polyp

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20
Q

Organism of appendix >

A

yersinia
CMV
enterobious vermicualris
Staphylo
E coli
Klebsilla
proteus

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21
Q

why blackish colour <

22
Q

types of acute appendicitis >

A

early acute A
acute suppurative A
acute gangrenoius A

23
Q

confiramtion of appendictis ?

A

histopathology

24
Q

macro of acute gangrenous appendictis >

A

swollen
distended
serosal covering - reddened
cut section - lumen filled with pus
mucosa shows - ulceration

25
carcinoid tumor site ?
tip of appendix
25
Micro of appendictis >
infiltration of acute inflammatory cells - neutrophilic leukocytosis - throughout the mucosa sub-mucosa and muscularis propria gap between muscle fiber - edema
26
complications of Acute G A ?
Appendicular lump A abscess gangrene of appendix 'perforation peritonitis pyelonephritis liver abscess pelvic abscess subphrenic abscess bacteraemia
26
why neutrophil more in muscularis mucosa <
rich vascular supply faciliate N migration
26
most common ?
neuroendocrine / carcinoid tumor
27
carcinoma of appendix >
Carcinoid tumor adenoma adenocarcinoma mucinous cystadenoma m cystadenocarcinoma
27
other sites of carcinoid tumor ?
lung stomach intestine
28
Neuroendocrine tumor arise from where??
neuroendocrine cells enterochromaffin cells argentafin cells
29
Stain of carcinoid tumor ?
silver stain -------- black
30
why gangrene in AGA ?
vascular compression G sudden ischemia + inflamamtion
31
fecalith what ><
stone like mass of stool 186
32
what is polyp ?
tumourous mass that protrudes into the lumen of the gut
33
non-neoplastic intestinal polyp ?
hyperplastic inflammatory hamartomatous -juvenile -peutz jeghers polyp
34
neoplastic polyp ?
tubular adenoma tubulovillous adenoma villous adenoma sessile serrated adenoma 185
35
CD vs UC ??????????????
181
36
No skip lesions seen in ?
UC
37
what is pseudomyxoma peritoneii ?
a mucus secreting appendicular carcinoma / ovarian carcinoma may fill the peritoneal cavity with gelatinous neoplastic mass
38
WHich IBD ulcer is deep ?
CD
39
kinfe like ulcer <
CD
40
Toxic megacolon present >
UC
41
CD vs Coeliac D ? 176
CD = inflammatory + deep + transmural + medication + surgery coelaic D = autoimmune + mucosa of SI + gluten free diet
41
maximum malignant potential polyp which one ?
villous adenoma
42
GIST defination ?
mesenchymal tumor derived from the intestinal cells of cajal / pacemaker cells of the GI muscularis propria 165
43
Macro of UC ?
continuous involvement no skip lesions mucosa shows - linaer + superficial ulcer apperance of pesudopolyp tips of this polyp fuse ---- mucosal bridges
44
UC or CD which one is more prone to malignancy ?
UC
45
GIST ??
Gastrointestinal stormal tumor
46
why no stricture in UC >
not transmural serosal surface normal