Gastrointestinal System - Small & Large Intestine Flashcards
Inflammatory Bowel Disease defination ?
Chronic condition
resulting from
complex interactions between intestinal microbiota & host immunity
in a genetically pre-disposed individuals t
that leads to
inappropriate mucosal immune activation
Crohn d site ?
any area of GI tract
Ulcerative colitis site ?
colon
rectum
specific sites of crohns disease >
terminal ileum
ileocecal valve
cecum
Crohn disease extent ?
transmura;
Ulcerative colitis extent >
mucosa & sub-mucosa
regional enteritis which one <
crohns disease
what is skip lesion?
sharply delineated areas in crohns d
179
macro of crohns D ?
179
distribution of CD
179
multiple
separate
skip lesions
wall of CD ?
All layer - inflamamtion
stricture - fistula - adhesions
narrow lumen X ray seen ?
String sign
mucosa of lumen feartures ?
serpiginous ulcer
= aphthous ulcer
mesenteric fat of macro ?
creeping fat
intervening surviving mucosa appearance >
cobblestone appearance
hallmark of crohns D >
non-caseating granuloma
Micro features of CD ?
179
transmural infiltration
patchy ulceration
epithelial metaplasia
loss of crypt epithelium
carcinoid tumor sites ?
appendix
terminal ileum
colon
rectum
lung
stomach
gall bladder
meckels diverticulum
182
Acute appendicitis etiology >
small stone like mass of stool = fecalith
gall stone
worms - oxyuriasis vermicularis
any tumor in the opening of appendix - benign polyp
Organism of appendix >
yersinia
CMV
enterobious vermicualris
Staphylo
E coli
Klebsilla
proteus
why blackish colour <
Gangrene
types of acute appendicitis >
early acute A
acute suppurative A
acute gangrenoius A
confiramtion of appendictis ?
histopathology
macro of acute gangrenous appendictis >
swollen
distended
serosal covering - reddened
cut section - lumen filled with pus
mucosa shows - ulceration