Female - Breast Flashcards
congenital anomalies of breast ?
supernumerary nipple/breast
amastia
congenital nipple inversion
accessory axillary breast tisssue
inflmmatory diseases of breast ?
acute mastitis
periductal mastitis
/// zuska D
duct ectasia
fat necrosis
lymphocytis mastitis
292
chronic inflammation to cancer
= example ?
pseu-d-orange
benign stromal tumor ?
intralobular
fibroadenoma
phyllodes tumor
interlobular
myofibroblastoma
lipoma
bening epithelial tumor
intraductal papilloma
in situ malignant ?
ductul carcinoma in situ
lobular carcinoma in situ
malignant invasive carcinoma ?
invasice ductul ca
invasive lobular ca
tubular ‘
medullary
mucinous
papillary
metaplastic
inflmmatory
pre-malignant cancer of breast ?
atypical ductul hyperplasia
atypical lobular hyperplasia
293
fibroadenoma other name ?
B mouse
why B mouse ?
easily moveable under skin
source of fibroadenoma ?
stroma
young women complain in fibroadenoma ?
palpable mass
old women complain <
cluster calcification
mammographic density
breast lump which c calcification?
cluster
Gross of fibroadenoma ?
well circumscribed \
rubbery’
freely moveable nodules
vary in size – <1cm to large tumor
cut surface - firm = grayish white
slit like spaces
20 years er female breast lump niye asle Dx ?
fibroadenoma
histo of fibroadenoma ?
intracanalicular + pericanalicular pattern
invasive ductal carcinoma gross ?
irregular
hard-cartilage like mass
well circumscribed
softer consistency
characteristics grating sound - cutting a water chestnut
cookie cutter space e ki thake >
desmoplasia = stony hard
nottingham grading system - content ?
tubule formation
nuclear pleomorphism
mitotic state
male vs female breast = ?
female B have - lobule
painful lump cause ?
periductal mastitis
abscess
fibroadenosis
299
painless lump ??
lipoma
fibroadenoma
haematoma
antibioma
fat necrosis
ekjon women Dr er kache ki ki problem niye ase >
lumpiness
pain
palpable mass
nipple discharge
tumor marker of breasr ?
CA=15-3
p53
CEA
germline mutation of 🤱 ?
BRCA+ CHEK-2
Phyllodes tumor vs fibroadenoma ?
- high cellularity
- high mitotic rate
-nuclear pleomorphism
-stromal overgrowth
-infiltrating border
300
molecular classificATION of breast ca ?
luminal A
luminal B
HER-2 enriched
basal like - triple negative
worst prognosis which type >
basal like
good prognosis .
luminal-A
why good prognosis >
luminal-A responds well to endocrine therapy
lUMINAL A = ?
PR ER strongly +
HER2 -
ER + PR lab Dx = ?
IHC
Luminal B = ?
ER PR low +
HER2 -
HER2 enriched = ?
HER2 +
ER PR -/+
basal like ?
ER PR HER2 = -
role of tamoxifen ?
ER +
estrogen therapy
hormone thrapy name ?
tamoxifen
aromatase inhibitors
schirrous carcinoma = ?
stony hard
desmoplasia example let alone breast ?
stomach
letther bottle war
breast cancer tumor type ?
tumor suppressor gene
metastatic site of breast ?
bone
liver
brain
regional lymphnode
biopsy type ?
core
excision
maximum ca breast are ————– ?
adenocarcinoma = >95%
age of fibroadenoma ?
20-30 years
maligant phyllodes are called ?
cystosarcoma phyllodes
types of phyllodes ?
B
M
borderline
peau-d-orange = ?
298
invasive carcinoma
= lymphatics become very involved
= block the local area of skin drainage
= cause lymphoedema
= thickening the skin
= edematous skin is tethered to the breast by Cooper ligament
orange peel
risk factors of breast cancer ?
302
prognostic factors of breast ca ?
303
common invasive carcinoma >
-invasive ductal carcinom a
70-80%
main 3 points of prognostic factor ?
distant metastasis
local invasion
nodal involvement
investigation of cancer /
300
history taking ?
299
examination of Breast ca ?
299
what is fibrocystic change /
beningn non-proliferative breast changes
adenosis ?
inc in the number of acini per lobules
investigations name ?
mamography
USG
MRI
cytology of nipple discharge
FNAC
biopsy
tumor marker
IHC
FISH
molecular Dx
another type of bopsy ?
image guided core needle biopsy
ductal ca specimen why formalin ?
10%
na rakhle - autolysis
10-2-2025
1.22PM
