Female - Breast

Question 1

congenital anomalies of breast ?

Answer 1

supernumerary nipple/breast
amastia
congenital nipple inversion
accessory axillary breast tisssue

Question 2

inflmmatory diseases of breast ?

Answer 2

acute mastitis
periductal mastitis
/// zuska D
duct ectasia
fat necrosis
lymphocytis mastitis

292

Question 3

chronic inflammation to cancer
= example ?

Answer 3

pseu-d-orange

Question 4

benign stromal tumor ?

Answer 4

intralobular

fibroadenoma
phyllodes tumor

interlobular
myofibroblastoma
lipoma

Question 5

bening epithelial tumor

Answer 5

intraductal papilloma

Question 6

in situ malignant ?

Answer 6

ductul carcinoma in situ
lobular carcinoma in situ

Question 7

malignant invasive carcinoma ?

Answer 7

invasice ductul ca
invasive lobular ca
tubular ‘
medullary
mucinous
papillary
metaplastic
inflmmatory

Question 8

pre-malignant cancer of breast ?

Answer 8

atypical ductul hyperplasia
atypical lobular hyperplasia

293

Question 9

fibroadenoma other name ?

Answer 9

B mouse

Question 10

why B mouse ?

Answer 10

easily moveable under skin

Question 11

source of fibroadenoma ?

Answer 11

stroma

Question 12

young women complain in fibroadenoma ?

Answer 12

palpable mass

Question 13

old women complain <

Answer 13

cluster calcification
mammographic density

Question 14

breast lump which c calcification?

Answer 14

cluster

Question 15

Gross of fibroadenoma ?

Answer 15

well circumscribed \
rubbery’
freely moveable nodules
vary in size – <1cm to large tumor
cut surface - firm = grayish white
slit like spaces

Question 15

20 years er female breast lump niye asle Dx ?

Answer 15

fibroadenoma

Question 16

histo of fibroadenoma ?

Answer 16

intracanalicular + pericanalicular pattern

Question 17

invasive ductal carcinoma gross ?

Answer 17

irregular
hard-cartilage like mass
well circumscribed
softer consistency
characteristics grating sound - cutting a water chestnut

Question 18

cookie cutter space e ki thake >

Answer 18

desmoplasia = stony hard

Question 19

nottingham grading system - content ?

Answer 19

tubule formation
nuclear pleomorphism
mitotic state

Question 20

male vs female breast = ?

Answer 20

female B have - lobule

Question 21

painful lump cause ?

Answer 21

periductal mastitis
abscess
fibroadenosis

299

Question 22

painless lump ??

Answer 22

lipoma
fibroadenoma
haematoma
antibioma
fat necrosis

Question 23

ekjon women Dr er kache ki ki problem niye ase >

Answer 23

lumpiness
pain
palpable mass
nipple discharge

Question 24

tumor marker of breasr ?

Answer 24

CA=15-3 p53 CEA

Question 25

germline mutation of 🤱 ?

Answer 25

BRCA+ CHEK-2

Question 26

Phyllodes tumor vs fibroadenoma ?

Answer 26

- high cellularity - high mitotic rate -nuclear pleomorphism -stromal overgrowth -infiltrating border 300

Question 27

molecular classificATION of breast ca ?

Answer 27

luminal A luminal B HER-2 enriched basal like - triple negative

Question 28

worst prognosis which type >

Answer 28

basal like

Question 29

good prognosis .

Answer 29

luminal-A

Question 30

why good prognosis >

Answer 30

luminal-A responds well to endocrine therapy

Question 31

lUMINAL A = ?

Answer 31

PR ER strongly + HER2 -

Question 32

ER + PR lab Dx = ?

Answer 32

IHC

Question 33

Luminal B = ?

Answer 33

ER PR low + HER2 -

Question 34

HER2 enriched = ?

Answer 34

HER2 + ER PR -/+

Question 35

basal like ?

Answer 35

ER PR HER2 = -

Question 36

role of tamoxifen ?

Answer 36

ER + estrogen therapy

Question 37

hormone thrapy name ?

Answer 37

tamoxifen aromatase inhibitors

Question 38

schirrous carcinoma = ?

Answer 38

stony hard

Question 39

desmoplasia example let alone breast ?

Answer 39

stomach letther bottle war

Question 40

breast cancer tumor type ?

Answer 40

tumor suppressor gene

Question 41

metastatic site of breast ?

Answer 41

bone liver brain regional lymphnode

Question 42

biopsy type ?

Answer 42

core excision

Question 42

maximum ca breast are -------------- ?

Answer 42

adenocarcinoma = >95%

Question 43

age of fibroadenoma ?

Answer 43

20-30 years

Question 44

maligant phyllodes are called ?

Answer 44

cystosarcoma phyllodes

Question 45

types of phyllodes ?

Answer 45

B M borderline

Question 46

peau-d-orange = ? 298

Answer 46

invasive carcinoma = lymphatics become very involved = block the local area of skin drainage = cause lymphoedema = thickening the skin = edematous skin is tethered to the breast by Cooper ligament orange peel

Question 47

risk factors of breast cancer ?

Answer 47

302

Question 48

prognostic factors of breast ca ?

Answer 48

303

Question 49

common invasive carcinoma >

Answer 49

-invasive ductal carcinom a 70-80%

Question 50

main 3 points of prognostic factor ?

Answer 50

distant metastasis local invasion nodal involvement

Question 51

investigation of cancer /

Answer 51

300

Question 52

history taking ?

Answer 52

299

Question 53

examination of Breast ca ?

Answer 53

299

Question 54

what is fibrocystic change /

Answer 54

beningn non-proliferative breast changes

Question 55

adenosis ?

Answer 55

inc in the number of acini per lobules

Question 56

investigations name ?

Answer 56

mamography USG MRI cytology of nipple discharge FNAC biopsy tumor marker IHC FISH molecular Dx

Question 57

another type of bopsy ?

Answer 57

image guided core needle biopsy

Question 58

ductal ca specimen why formalin ?

Answer 58

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