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Pathology-Medical-Prof > Endocrine-Thyroid Gland > Flashcards

Endocrine-Thyroid Gland Flashcards

1
Q

congenital anomlaies of thyroid galnd ?

A

thyroglossal duct
thyroglossal cyst
lingual thyroid
median ectopic thyroid
lateral aberrant thyroid

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2
Q

benign tumor of T ?

A

follicular adenoma

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2
Q

tumors of thyroid ??

A

307

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3
Q

primary malignanct tumor of thyroid ?

A

papillary
follicular
anaplastic
medullary

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4
Q

secondary malignant tumor of thyroid ?

A

metastatic
local infiktration

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5
Q

goitre ??

A

enlargement of thyroid gland
313

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6
Q

pre-malignanct tumor of thyroid gland ?

A

thyroid cyst
follicular adenoma
C-cell hyperplasia
carcinoid tumor of thyroid
solitary thyroid nodule

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7
Q

common thyroid tumor ?

A

papillary = 80-85%

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8
Q

gross of papillary carcinoma of thyroid ?

A

solitary / multi focal lesion
well-circumscribed + encapsulated
contain area of fibrosis + calcification
papillary foci that point to the diagnosis

318

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9
Q

microscopic of papillary ?

A

branching papillae - having fibrovascular stalk - covered by cuboidal epithelium
nuclei - optically clear _ empty = ground glass appearance = orphan annie eye nuclei
concentrically calcified structure [ psammoma bodies

318

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10
Q

what is orphan annie eye ?

A

nuclei - optically clear _ empty = ground glass appearance = orphan annie eye nuclei

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11
Q

prognosis of papillary ca ?

A

good

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12
Q

why prognosis good /

A

low rate of distant metastasis

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13
Q

psammoma bodies example ?

A

319

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14
Q

example of capsulated malignant tumor ?

A

renal cell ca
papillary ca of thyroid

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15
Q

non-capsulated beningn tumro ?
210

A

lymphanghioma
haemangioma
leiomyoma
neurofibroma
papilloma
adenoma

210

16
Q

age of papillary ca ?

17
Q

cell of origin of papillary carcinoma ?

A

follicular

18
Q

cell of origi n of medullary ?

A

parafollicular cell

19
Q

other name of para-follicular cell ?

A

C-cell

321

20
Q

which ca is worst in thyroid ?

A

anaplastic

21
Q

follicular VS papillary >?

22
Q

lacking of folicular tumor in contrast with papillary tymor ?

A

papillae
ground glass n /OAEN
psammoma bodies

23
Q

age of anaplastic ca ?

24
Q

gross of follicular ca ?

A

single nodules
well-circumscribed
larger lesion may penetrate the capsule
grat to tan to pink
central fibrosis + area of calcification

25
Q

microscopic of follicular Ca ?

A

fairly uniform cell - forming folliclee of various sizes containg colloid
abundant granular _ eosniophilic cytoplasm = hurthle cell
vascular invasion
direct ectensiuon in to the capsule

26
Q

stain for medullary ca ?

A

calcitonin
CEA

27
Q

hormone of medullary ca ?

A

CEA
chromogranin
synaptophysin

321

28
Q

excat age of papillary ca /

29
Q

lymphatic metastasis of medullary ca ?

A

breast
gastric
bronchogenic

Pathology-Medical-Prof (35 decks)

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