Diseases Of Lymphatics

Question 1

what is lymphadenopathy ??

Answer 1

when 2/more groups of lymph node are enlarged

Question 2

causes of lymphadenopathy ?

Answer 2

lymphoma
leukaemia
SLE
RA
CMV HIV
Filariaisis
toxoplasmosis
syphilis
TB brucellosis cat scracth D

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Question 3

Lymphoma defination ?

Answer 3

neoplastic proliferation of cells native to the lymph nodes

Question 4

WHO classification of hodgkin lymphoma ?

Answer 4

Classical
non-classical

Question 4

classification of lymphoma ?

Answer 4

Hodgkin
Non-H

Question 5

Classical HL types >?n

Answer 5

nodular
mixed cellularity
lymphocyte rich
lymphocyte depleted

Question 6

Non-classical HL ?

Answer 6

lymphocyte predominant
77

Question 7

hall mark of HL ?

Answer 7

RS cells

Question 7

what is Reed sterberg cells >

Answer 7

malignant lymphoid cells of B cell origin

Question 8

Major hallmark of HL >

Answer 8

RS cells
pleomorphic infiltration

Question 9

RS cells diameter ?

Answer 9

45 micro meter

Question 10

Characteristics of RS cells ?

Answer 10

1.bi-lobed nucleus = two halves = mirror image

2.nucleus = contain = inclusion like nucleolus = surrounded by a clear zone (halo) = owl eye appearance

3.nucleus = surround by T lymphocyte + plasma cells + eosinophilic cytopolasm

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Question 11

why owl eye appearance??

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Answer 11

nucleus = contain = inclusion like nucleolus = surrounded by a clear zone (halo) = owl eye appearance

Question 12

lacunar cell in which subtypes ?

Answer 12

nodular sclerosis

Question 12

nucleus condition in RS cells

Answer 12

3.nucleus = surround by T lymphocyte + plasma cells + eosinophilic cytopolasm

Question 13

other example of RS cells ?

Answer 13

infectious mononulceosis
CLL
non-HL
solid tissue cancer

Question 13

RS cells type ?

Answer 13

mononuclear
lacunar
lympho-histocytic

Question 14

special appearance of RS cells ?

Answer 14

pop-corn cell

Question 14

why popcorn cell ?

Answer 14

puffy n
abundant pale cytoplasm
= popped corn

Question 15

lympho-histocytic in which sub-type ?

Answer 15

Lymphocyte predominant

Question 16

most common subtype ?

Answer 16

nodular sclerosis

Question 17

HL classification by whom ?>?

Answer 17

WHO

Question 18

non-HL etiology ?

Answer 18

virus -HCV HHV-8 HIV

Question 19

what is burkitt lymphoma ?

Answer 19

translocation of the MYC gene on chromosome-8 that lead to inc MYC protein level

Question 20

RS cell in which process in lympho-histocytic type ?

Answer 20

mummification 79

Question 21

kader hoy ?

Answer 21

HIV pt children

Question 22

Burkitt lymphoma kothay hoy ?

Answer 22

Jaw facial bones

Question 23

Burkitt lymphoma type ?

Answer 23

B cell lymphoma

Question 24

T cell lymphoma example ?

Answer 24

Mycosis fungoides

Question 25

One specific features of BL ?

Answer 25

t-(8-14) chromosomal translocation

Question 26

morphology of BL >

Answer 26

Starry sky appearance inc mitotic index ' apoptotic cells abundant clear cytoplasm

Question 27

which L high cure rate?

Answer 27

HL

Question 28

which one is bad ?

Answer 28

non-HL

Question 29

Lymph node examination of hl >

Answer 29

FNAC Biopsy histopathology

Question 30

FNAC type for HL ?

Answer 30

Excisional / image guided biopsy

Question 31

CBC of L ?

Answer 31

Platelet = normal inc ESR eosniophilia

Question 32

PBF of L ?

Answer 32

normochromic normocytic

Question 33

BM of L ?

Answer 33

Leukoerythroblastic blood picture

Question 34

IHC of L ?

Answer 34

CD - 15 20 30

Question 35

Lymph node involvement in HL ?

Answer 35

single axial

Question 36

lymph node involvement in Non-HL ?

Answer 36

Multiple peripheral nodes

Question 37

extranodal involvemnet less ?

Answer 37

HL

Question 38

HL vs Non-HL ??????????//

Answer 38

82

Question 39

follicular hyperplasia vs Follicular lymphoma ?

Answer 39

85

Question 40

Systemic features and B symtpoms and Pruritis more common in ?????????/

Answer 40

HL

Question 41

Mesenteric node epitrochlear node weldeyer ring involvement less ?

Answer 41

HL

Question 42

presence nodal architecture?

Answer 42

f hyperplasia

Question 43

follicles site in both ?

Answer 43

F h = Follicles - centre F l = F = centre + medulla

Question 44

Follicles shape >?

Answer 44

F h = variation in size and shape F l = uniform

Question 45

mantle cell in both ?

Answer 45

F h = MC = dictinct F l = MC = indisxinct 11-2-2025 12.44PM