Carcinogens Flashcards by Istiak Mahmud Siam | Brainscape

Q

Carcinogens definition ??

A

Agents that cause genetic damage induce neoplastic transformation of cells

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Q

Classification of carcinogens ??

A

Chemical carcinogens
Radiant energy
Oncogenic virus and microbes

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Q

A

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Q

Radiant carcinogenesis cause ??

A

Uktraviolet ray from Sun

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Q

UV ray cause which Ca ??

A

Basal cell Ca
Squamous cell Ca
Maliganant melanoma skin

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A

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Q

Oncogenic bacteria ??

A

H pylroi
Campylobacter jejuni

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Q

Oncogenic parasite ??

A

ClonORchis sinensis
Schistosoma
Opisthorchis
Liver flukes

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Q

Oncogenic fungus ??

A

Aspergillus flavus
Aflatoxin

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Q

Small - Round - Blue cell tumor in H&E stain ??

A

Wilms tumor
Ewing tumor
Lymphoma
Rhabdomyosarcoma
Neuroblastoma
Retinoblastoma

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Q

Benign tumor of childhood ??

A

Hemangioma
Fibrous tumor
Teratomas
Mature & Immature teratomas
Fibromatosis

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Q

Ewing tumor chromosome translocation ??

A

t-(11,22)

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Q

Common malignant of childhood

A

Wilms tumor
Ewing tumor
Lymphoma
Rhabdomyosarcoma
Neuroblastoma
Retinoblastoma

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Q

Xray of ewing tumor ??

A

Onion like

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Q

Site of ewing tumor ??

A

Diaphysis

Pathoma-199

Q

Malignant tumor of kidney ??

A

Wilms tumor

Q

Wilms tumor comprised of –

A

Blastema
Tubules
Stromal cells
Primitive glomeruli

pathoma-134

Q

Presentation of wilms tumor ??

A

Unilateral flank
HTN
Hematuria

P-134

Q

WARG syndrome ??

A

Wilms tumor
Aniridia
Genital abnormalities
Mental & motor retardation

Q

`

Beckwith-Wiedemann syndrome ??

A

Wilms tumor
Neonatal hypoglycemia
Organomegaly
Muscular hemihypertrophy `

WT2 gene

Q

WARG syndrome deletion ??

A

WT1 - Tumor suppressor gene - 11p13

Q

Denys Drash syndrome ??

A

Wilms tumor
Renal glomerular disease
Male pseudohermaphroditism

134

WT1