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Pathology-Medical-Prof > Carcinogens > Flashcards

Carcinogens Flashcards

1
Q

Carcinogens definition ??

A

Agents that cause genetic damage induce neoplastic transformation of cells

228

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2
Q

Classification of carcinogens ??

A
  1. Chemical carcinogens
  2. Radiant energy
  3. Oncogenic virus and microbes

228

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3
Q
A
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3
Q

Radiant carcinogenesis cause ??

A

Uktraviolet ray from Sun

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4
Q

UV ray cause which Ca ??

A
  1. Basal cell Ca
  2. Squamous cell Ca
  3. Maliganant melanoma skin
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5
Q
A
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5
Q
A
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6
Q

Oncogenic bacteria ??

A
  1. H pylroi
  2. Campylobacter jejuni

229

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7
Q

Oncogenic parasite ??

A
  1. ClonORchis sinensis
  2. Schistosoma
  3. Opisthorchis
  4. Liver flukes

229

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7
Q

Oncogenic fungus ??

A

Aspergillus flavus
Aflatoxin

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8
Q

Small - Round - Blue cell tumor in H&E stain ??

A
  1. Wilms tumor
  2. Ewing tumor
  3. Lymphoma
  4. Rhabdomyosarcoma
  5. Neuroblastoma
  6. Retinoblastoma

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9
Q

Benign tumor of childhood ??

A
  1. Hemangioma
  2. Fibrous tumor
  3. Teratomas
  4. Mature & Immature teratomas
  5. Fibromatosis

257

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9
Q

Ewing tumor chromosome translocation ??

A

t-(11,22)

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10
Q

Common malignant of childhood

A
  1. Wilms tumor
  2. Ewing tumor
  3. Lymphoma
  4. Rhabdomyosarcoma
  5. Neuroblastoma
  6. Retinoblastoma
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11
Q

Xray of ewing tumor ??

A

Onion like

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12
Q

Site of ewing tumor ??

A

Diaphysis

Pathoma-199

13
Q

Malignant tumor of kidney ??

A

Wilms tumor

14
Q

Wilms tumor comprised of –

A
  1. Blastema
  2. Tubules
  3. Stromal cells
  4. Primitive glomeruli

pathoma-134

15
Q

Presentation of wilms tumor ??

A
  1. Unilateral flank
  2. HTN
  3. Hematuria

P-134

16
Q

WARG syndrome ??

A
  1. Wilms tumor
  2. Aniridia
  3. Genital abnormalities
  4. Mental & motor retardation
17
Q

`

Beckwith-Wiedemann syndrome ??

A
  1. Wilms tumor
  2. Neonatal hypoglycemia
  3. Organomegaly
  4. Muscular hemihypertrophy `

WT2 gene

17
Q

WARG syndrome deletion ??

A

WT1 - Tumor suppressor gene - 11p13

18
Q

Denys Drash syndrome ??

A
  1. Wilms tumor
  2. Renal glomerular disease
  3. Male pseudohermaphroditism

134

WT1

Pathology-Medical-Prof (35 decks)

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