Female - Ovary+Trophoblastic Disease

Question 1

WHO classification of ovarian tumor ?

Answer 1

280-281

Question 2

dermoid cyst other name ?

Answer 2

benign cystic teratoma

Question 2

sex cord stromal tumor ?

Answer 2

granulosa theca cell
fibroma
thecoma
fibrothecoma

sertoli leydig cell
steroid/lipid cell tumor

Question 3

teratoma type ?

Answer 3

bening
malignant
monodermal/specialized

Question 3

classify ovarian cyst ?

Answer 3

282

Question 4

NON-NEOPLASTIC & functional ovarian cycst ?

Answer 4

follicular
leuteal
chocolate
PCOS

Question 5

Neoplastic cyst ?

Answer 5

surface epithelium
- S/M cycstadenoma
-S/M cystadenocarcinoma
germ cell tumors - dermoid cyst

Question 6

microscopic of dermoid cyst ?

Answer 6

cyst wall lined by – skin + hair follicles + skin appendages

structures from other germ layers – cartilage + bone + GI + neural + respiratory + thryoid gland

283

Question 6

gross/macroscopic of dermoid cyst ?

Answer 6

bilateral
unilocular cyst
contain hair + cheesy sebaceous material
cyst wall thin + opaque grey white
from epidermis hair follicles protrude
wall= tooth structure + areas of calcification

283

Question 7

stuma ovarii of teratoma cell ?

Answer 7

thyroid tissue === hyperthyroidism

Question 7

chance of malignancy of dermoid cyst ?

Answer 7

1 % = SCC
THYROID CARCINOMA
MELANOMA

Question 8

Hormone producing tumor of ovary ?

Answer 8

285

Question 9

Thecoma hormone name ?

Answer 9

estrogen

Question 10

germ cell tumor in male ?

Answer 10

seminoma

Question 11

choriocarcinoma hormone ?

Answer 11

HCG

Question 12

sertoli leydig cell tumor hormone ?

Answer 12

androgen

Question 13

granulosa cell tumor hormone ?

Answer 13

estrogen

Question 14

malignant teratoma name ?

Answer 14

teratocarcinoma

Question 15

chocolate cyst pathophysilogy ??

Answer 15

mens cycle === bleeding — blood – -RBC === hemosiderin — golden brown – chocolate colour

Question 16

krukenberg tumor ?

Answer 16

metastatic gastrointestinal carcinoma involving the ovaries

Question 17

K tumour apperance ?
285

Answer 17

mucin secreting cancer cells
signet cells
bilateral metastatsis

Question 18

meigs syndorme ?

Answer 18

ovarian fibroma
ascites
hydrothorax

Question 19

Lab Dx of ovarian tumor ?

Answer 19

286

Question 20

germ cell tumor marker ?

Answer 20

AFP
Serum beta -hCG

Question 21

epithelial ovarian tumor --- tumor marker ?

Answer 21

CA-125 CA-72-4 CA-19-9 CEA- carcinoembryonic antigeen

Question 22

Sex cord stomal tumor amrker ?

Answer 22

Estradiol

Question 23

FNAC type .

Answer 23

USG guided

Question 24

Dx confrim by ?

Answer 24

Histopathology

Question 25

teratoma ??

Answer 25

totipotent germ cell - it contains derivatives of all 3 germ layers - predominately ectoderm

Question 26

germ cell tumor of female >

Answer 26

dysgermonoma

Question 27

dysgerminoma gross /

Answer 27

unilateral solid tumor size from - barely visiblenodules to massess that fill entire abdomen cut surfacr - yellow white ---- gray pink foci of H + N 284

Question 28

histo of dysgerminoma .

Answer 28

arranged in diffuse sheets seprated b y fibrous stroma fibrous stoma = mature lymphocyte + granuloma

Question 29

examples of gestational trophoblastic disease ?

Answer 29

hydatidiform mole invasive mole placental site trophoblastic tumor choriocarcinoma

Question 30

hydatidiform mole hormone ?

Answer 30

beta =HCG

Question 31

complete HM /

Answer 31

no embryo 46 XX 2 sperm + empty egg

Question 32

fertilization of an egg that loss its female chromosome ?

Answer 32

complete HM

Question 33

partial HM ?

Answer 33

69XXY triploidy / tetraploidy = 92XXXY 2 sperm + 1 egg

Question 34

complete vs partial HM ?

Answer 34

289

Question 35

which HM have more chance of choriocarcinoma /

Answer 35

complete HM

Question 36

Macro of HM ?

Answer 36

uterine cavity is filled with delicate friable mass of thin walled translucent cystic grape-like structure swollen edematous villi

Question 37

fetal tissue + blood vessel = present ?

Answer 37

Partial mole

Question 38

villous tissue condition in CHM ?

Answer 38

all/most of the villous tissue

Question 39

hydatidiform mole defination ?

Answer 39

cystic swelling of cchorionic villi accompanied by variable trophoblastic proliferation

Question 40

USG of HM ?

Answer 40

Snowstorm appearance of moles

Question 41

serum HCG in CHM ?

Answer 41

elevated

Question 42

lab Dx of HM ?

Answer 42

290

Question 43

URINE pregnancy test in HM ?

Answer 43

+

Question 44

Sites of choriocarcinoma ?

Answer 44

testis ovary gestational trophoblastic epithelium

Question 45

how to differentiate all type of gestational disease ?

Answer 45

by preganancy test

Question 46

in all cases 🤰 test in urine result ?

Answer 46

+

Question 47

P test in 🤰?

Answer 47

result = - in 100 times dilutions

Question 48

P test in HM ?

Answer 48

result = + even in 300-500 times dilution

Question 49

P test in Choriocarinoma ?

Answer 49

result = + even more than 1000 times di8lution

Question 50

urinary beta-HCG in P ?

Answer 50

< 1 lac

Question 51

in trophoblastic tumor ? Beta HCG ??

Answer 51

>1 lac <5 lac

Question 52

what choriocarcinoma shows ?

Answer 52

ischemic necrosis extensive hemorrhage

Question 53

Gestational choriocarcinoma VS non-gestational C

Answer 53

G C - have paternally derived DNA

Question 54

Metastasis of choriocarcinoma /

Answer 54

50%= lung (30-40)% = vagina brain - liver - bone - kidney 291

Question 55

inflammation of ovary is called /

Answer 55

Oophoritis

Question 56

inflammation of uterus ?

Answer 56

metritis

Question 57

nipple inflammation ?

Answer 57

thelitis

Question 58

pelvis inflammation ?

Answer 58

pyelitis

Question 59

umbilicus inflmmation ??

Answer 59

Omphalitis