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Pathology-Medical-Prof > Female - Ovary+Trophoblastic Disease > Flashcards

Female - Ovary+Trophoblastic Disease Flashcards

1
Q

WHO classification of ovarian tumor ?

A

280-281

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2
Q

dermoid cyst other name ?

A

benign cystic teratoma

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2
Q

sex cord stromal tumor ?

A

granulosa theca cell
fibroma
thecoma
fibrothecoma

sertoli leydig cell
steroid/lipid cell tumor

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3
Q

teratoma type ?

A

bening
malignant
monodermal/specialized

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3
Q

classify ovarian cyst ?

A

282

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4
Q

NON-NEOPLASTIC & functional ovarian cycst ?

A

follicular
leuteal
chocolate
PCOS

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5
Q

Neoplastic cyst ?

A

surface epithelium
- S/M cycstadenoma
-S/M cystadenocarcinoma
germ cell tumors - dermoid cyst

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6
Q

microscopic of dermoid cyst ?

A

cyst wall lined by – skin + hair follicles + skin appendages

structures from other germ layers – cartilage + bone + GI + neural + respiratory + thryoid gland

283

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6
Q

gross/macroscopic of dermoid cyst ?

A

bilateral
unilocular cyst
contain hair + cheesy sebaceous material
cyst wall thin + opaque grey white
from epidermis hair follicles protrude
wall= tooth structure + areas of calcification

283

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7
Q

stuma ovarii of teratoma cell ?

A

thyroid tissue === hyperthyroidism

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7
Q

chance of malignancy of dermoid cyst ?

A

1 % = SCC
THYROID CARCINOMA
MELANOMA

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8
Q

Hormone producing tumor of ovary ?

A

285

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9
Q

Thecoma hormone name ?

A

estrogen

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10
Q

germ cell tumor in male ?

A

seminoma

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11
Q

choriocarcinoma hormone ?

A

HCG

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12
Q

sertoli leydig cell tumor hormone ?

A

androgen

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13
Q

granulosa cell tumor hormone ?

A

estrogen

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14
Q

malignant teratoma name ?

A

teratocarcinoma

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15
Q

chocolate cyst pathophysilogy ??

A

mens cycle === bleeding — blood – -RBC === hemosiderin — golden brown – chocolate colour

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16
Q

krukenberg tumor ?

A

metastatic gastrointestinal carcinoma involving the ovaries

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17
Q

K tumour apperance ?
285

A

mucin secreting cancer cells
signet cells
bilateral metastatsis

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18
Q

meigs syndorme ?

A

ovarian fibroma
ascites
hydrothorax

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19
Q

Lab Dx of ovarian tumor ?

A

286

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20
Q

germ cell tumor marker ?

A

AFP
Serum beta -hCG

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21
Q

epithelial ovarian tumor
— tumor marker ?

A

CA-125
CA-72-4
CA-19-9
CEA- carcinoembryonic antigeen

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22
Q

Sex cord stomal tumor amrker ?

23
Q

FNAC type .

A

USG guided

24
Q

Dx confrim by ?

A

Histopathology

25
Q

teratoma ??

A

totipotent germ cell - it contains derivatives of all 3 germ layers - predominately ectoderm

26
Q

germ cell tumor of female >

A

dysgermonoma

27
Q

dysgerminoma gross /

A

unilateral
solid tumor
size from - barely visiblenodules to massess that fill entire abdomen
cut surfacr - yellow white —- gray pink
foci of H + N

284

28
Q

histo of dysgerminoma .

A

arranged in diffuse sheets seprated b y fibrous stroma
fibrous stoma = mature lymphocyte + granuloma

29
Q

examples of gestational trophoblastic disease ?

A

hydatidiform mole
invasive mole
placental site trophoblastic tumor
choriocarcinoma

30
Q

hydatidiform mole hormone ?

31
Q

complete HM /

A

no embryo
46 XX
2 sperm + empty egg

32
Q

fertilization of an egg that loss its female chromosome ?

A

complete HM

33
Q

partial HM ?

A

69XXY
triploidy / tetraploidy = 92XXXY
2 sperm + 1 egg

34
Q

complete vs partial HM ?

35
Q

which HM have more chance of choriocarcinoma /

A

complete HM

36
Q

Macro of HM ?

A

uterine cavity is filled with
delicate
friable mass of thin walled
translucent
cystic
grape-like structure
swollen edematous villi

37
Q

fetal tissue + blood vessel = present ?

A

Partial mole

38
Q

villous tissue condition in CHM ?

A

all/most of the villous tissue

39
Q

hydatidiform mole defination ?

A

cystic swelling of cchorionic villi
accompanied by
variable trophoblastic proliferation

40
Q

USG of HM ?

A

Snowstorm appearance of moles

41
Q

serum HCG in CHM ?

42
Q

lab Dx of HM ?

43
Q

URINE pregnancy test in HM ?

44
Q

Sites of choriocarcinoma ?

A

testis
ovary
gestational trophoblastic epithelium

45
Q

how to differentiate all type of gestational disease ?

A

by preganancy test

46
Q

in all cases 🤰 test in urine result ?

47
Q

P test in 🤰?

A

result = - in 100 times dilutions

48
Q

P test in HM ?

A

result = + even in 300-500 times dilution

49
Q

P test in Choriocarinoma ?

A

result = + even more than 1000 times di8lution

50
Q

urinary beta-HCG in P ?

51
Q

in trophoblastic tumor ? Beta HCG ??

A

> 1 lac
<5 lac

52
Q

what choriocarcinoma shows ?

A

ischemic necrosis
extensive hemorrhage

53
Q

Gestational choriocarcinoma VS non-gestational C

A

G C - have paternally derived DNA

54
Q

Metastasis of choriocarcinoma /

A

50%= lung
(30-40)% = vagina

brain - liver - bone - kidney
291

55
Q

inflammation of ovary is called /

A

Oophoritis

56
Q

inflammation of uterus ?

57
Q

nipple inflammation ?

58
Q

pelvis inflammation ?

59
Q

umbilicus inflmmation ??

A

Omphalitis

Pathology-Medical-Prof (35 decks)

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