Minerals - Sodium (Na+) and Chloride (Cl-) Flashcards

1
Q

Sodium (Na+) and Chloride (Cl-)

A
  • Sodium (Na+) Is the main extracellular cation in the body
  • In nature it is only found as a compound due to its high reactivity
  • It is most commonly bound to the anion chloride (Cl-) forming sodium chloride (NaCl), otherwise known as salt
  • All life has evolved to depend on its chemical properties
  • Humans have taste and appetite systems especially as salt
  • Common table salt is 40% sodium and 60% chloride by weight
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2
Q

Salt

A

Clients must be guided as to what salts they should use. There are a variety of salts:
* Table salt
* Sea salt
* Himalayan salt
* Grey/Celtic salt (a type of sea salt)

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3
Q

Table salt

A
  • A cellular poison that originates from salt mines (I.e. rock salt) but is then refined (other minerals are removed). It is heat-treated and bleached; anticaking agent such as aluminium are added.
  • The combination of just NaCl is highly damaging to cells. It has no nutritional value and contributes to hypertension, atherosclerosis, insulin resistance and cancers (i.e. gastric)
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4
Q

Sea salt

A
  • Made by evaporating seawater
  • It is unprocessed and hence has a high mineral content
  • May contain more impurities such as heavy metals (extremely low concentrations)
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5
Q

Himalayan salt

A
  • Sourced from ancient seabeds in the Himalayas
  • It contains slightly less sodium than table salt and includes 84 trace minerals (i.e. iron) which are responsible for the ‘pink’. It is the trace minerals that make the salt therapeutic
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6
Q

Grey/Celtic salt
(a type of sea salt)

A
  • Harvested from mineral rich clay and sand salt trays in France. The clay enhances the mineral content and contains more moisture than other salts.
  • Similar nutritional profile to Himalayan
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7
Q

RAAS and BP regulation

A

Plasma sodium is tightly controlled in the body, and its principal role is regulating extracellular fluid volume.
* When Na levels fall, renin is secreted by the kidneys, eventually stimulating the formation of angiotensin II in the lungs and the release of aldosterone from the adrenal cortex (RAAS)
* Aldosterone increases sodium (and subsequently water) reabsorption in the kidneys (increasing BP)
* Raised plasma sodium stimulates the release of antidiuretic hormone which stimulates renal reabsorption of water (increasing BP)

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8
Q

Food sources

A
  • Sodium and chloride are sufficiently present in most natural foods
  • However, approximately 70% of the sodium intake in the typical western diet comes from processed food or is added during food preparation

Food sources of sodium / per 100 g

Natural food:
Potatoes / 6 mg
Wheat flour / 2 mg
Milk / 44 mg
Corn / 35 mg
Pork / 62 mg

After processing:
French fries / 210 mg
French baguette / 670 mg
Cheddar cheese / 621 mg
Cornflakes / 729 mg
Bacon / 2193 mg

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9
Q

Daily intakes

A
  • Minimum daily requirements: < 500 mg
  • Maximum recommended daily Intake: 2300 mg
  • Average daily intake (West): 2000 - 14,000 mg
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10
Q

Functions: pH balance and BP

A

Functions: pH balance and BP
* Na and Cl help to maintain the acid–alkaline balance in the body
* Sodium increases water return and increases BP
Therapeutic uses:
* Electrolyte replacement
* Hypotension

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11
Q

Functions: Nerve transmission

A

Functions:
* Na is essential in nerve impulse transmission (sodium influx into a neuron = action potential)
* Controls muscle contractions
Therapeutic uses:
* Muscle cramps

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12
Q

Function: Digestion

A

Functions: Digestion
* Cl is a constituent of stomach acid – Hydrochloric acid (HCl)
Therapeutic uses:
* Hypochlorhydria

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13
Q

Deficiency

A
  • Like potassium sodium levels are very tightly regulated by the kidneys and, therefore, deficiency is difficult to induce
  • When it does occur, it is usually a result of a medical condition
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14
Q

Deficiency causes

A

Deficiency is rare, but causes may include:
* Persistent diarrhoea
* Vomiting
* Chronic renal disease
* Major trauma
* Cachexia (wasting condition)
* Overuse of diuretics
* Anorexia nervosa
* Excess water intake
* Liver disease
* Ulcerative colitis

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15
Q

Hypertension

A

Hypertension (high blood pressure):
* Eliminating table salt is a crucial intervention in hypertension due to its toxicity. In cases of hypertension, opt for healthy salt alternatives
* Excessive table salt intake can also contribute to coronary artery disease, strokes, gastric cancer, osteoporosis and asthma

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16
Q

Hypertension susceptibility

A

Individuals who appear to be more sensitive to high salt intake:
* Chronic kidney disease
* Diabetes mellitus
* Obesity or overweight people
* People over 50
* People of African origin
* Family history of hypertension
* Genetic variants of the ‘ACE’ gene (increased risk of high blood pressure)

17
Q

Functions

A

PH balance and BP
Nerve transmission
Digestion