mar 14 Flashcards
what is a common time of day for a medication overuse headache to occur?
early upon wakening
what are the DERMATOLOGIC clinical features of a cholesterol embolism?
livedo reticularis, ulcers, gangrene, blue toe syndrome
what are the RENAL clinical features of a cholesterol embolism?
acute or subacute kidney injury
what are CNS complications of a cholesterol embolism?
stroke, amaurosis fugax
what are GI features of a cholesterol embolism?
intestinal ischemia, pancreatitis
what are the lab findings in someone who has a cholesterol embolism?
elevated creatinine, eosinophilia, hypocomplementiemia
what will the findings be on renal biopsy in fat embolism
biconvex, needle shaped clefts within an occluded vessel
-perivascular inflammation with eosinophils
how is the urinalysis in a patient with cholesterol embolism?
usually benign - may be eosinophils
urinalysis findings after contrast induced nephropathy?
muddy-brown granular and epithelial cell casts
dense deposit disease =
membranoproliferative glomerulonephritis
path of membranoproliferative glomerulonephritis
igG antibodies directed towards the alternative complement pathway react with the C3 convertase, leading to persistant complement activation
why may bounding pulses be seen in septic patients
they have vasodilation but increased cardiac index (in the early phases)
what is aplastic crisis?
a transient arrest of erythropoeisis, that may occur secondarily to infection in a patient with sickle cell
lab findings in aplastic crisis?
anemia with low reticulocyte count
are WBC and platelet counts normal in aplastic crisis?
yes
