april 1 Flashcards

1
Q

what does VACTERL stand for?

A
vertebral
anal
cardiac
TrachoEsophageal fistula
Renal anomalies
Limb anomalies
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2
Q

A neonate has a tracheoesophageal fistula… what are you worried about?

A

VACTERL (more commonly)

or CHARGE syndrome

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3
Q

what is CHARGE syndrome?

A
Coloboma
Heart defects
Atresia
Retardiation of growth
Genitourinary abnormalities
Ear abnormalities
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4
Q

All neonates with a tracheoosophagela fistula should undergo which tests?

A
  • echocardiography

- renal ultrasound

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5
Q

what is pretest odds?

A

the odds of something happening/the odds of it not happening

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6
Q

symptoms of pellegra?

A

diarrhea
dermatitis
dementia/depression/distraction
death

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7
Q

what causes pellegra?

A

niacin deficiency

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8
Q

MOA of metoclopramide?

A

dopamine antagonist

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9
Q

aprepitant MOA

A

substance P NK1 antagonist

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10
Q

hydroxyzine MOA

A

antihistamines

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11
Q

odansetron MOA

A

serotonin 5HT3 antagonist

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12
Q

bite cells are seen in…

A

G6PD deficiency

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13
Q

target cells are seen in…

A

thalasemia

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14
Q

infants with hypothyroidism appear normal at…

A

birth (due to the mothers hormones in the infants circulation)

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15
Q

infants with hypothyroidism will gradually develop which features?

A
apathy
weakness
hypotonia
large tongue
abdominal bloating
umbilical hernia
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16
Q

what changes in hormones will be seen in a nonfunctioning pituitary adenoma?

A
  • decrease of most hormones (LH, FSH, TSH)

- mild increase in prolactin due to disruption of dopamine pathways that would suppress it

17
Q

nitroglycerin will alleviate pain not only from heart problems but also from…

A

esophageal spasm

18
Q

pathophys of henoch-schonlen purpura (igA vasculitis)?

A

deposition of igA, C3 and fibrin in small vessels

19
Q

igA vasculitis AKA

A

henoch-schonlein purpura

20
Q

manifestations seen in igA vasculitis?

A
  • palpable purpura/petechia on lower extremities
  • arthritis/arthralgia
  • abdominal pain/intussiception
  • renal disease
  • scrotal pain/swelling
21
Q

scrotal pain may be seen in which vasculitis?

A

igA vasculitis

22
Q

what is the EPO level in polycythemia vera?

23
Q

treatment of polycythemia vera?

A

Phlebotomy

and maybe hydroxyurea

24
Q

what medications can be used to treat essential tremor?

A

beta blockers

anticonvulsants

25
beta blockers are contraindicatd in patients with...
reactive airway disease (asthma, COPD) or heart block
26
nitrates releive chest pain via...
decreased left ventricular wall stress (due to decreased preload and afterload)
27
what factors may trigger psoriasis?
- local skin trauma - withdrawal from steroids - medications - HIV and strep pharyngitis
28
A patient has sudden onset severe psoriasis and a history of STIs. Consider testing for...
HIV
29
presentation of hodgkin lymphoma?
- painless lymphadenopathy - mediastinal mass - B symptoms (fever, night sweats) - pruritis
30
diagnosis of hodgkin lymphoma?
- lymph node biopsy | - reed sternberg cells
31
why may patients with hodgkin lymphoma have pruritis?
release of cytokines
32
ECG findings in stress induced cardiomyopathy (takotsubo)?
evidence of ischemia in anterior precordial leads
33
ECG findings suggested cardiac ischemia but no obstructions found on catheterization =
stress induced cardiomyopathy (takotsubo)
34
stress induced cardiomyopathy is characterized by ...... hypokinesis
left ventricular mid and apical segment and basilar
35
treatment of GBS?
IVIG or plasmapheresis