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Pathology > Male Genital Tract > Flashcards

Male Genital Tract Flashcards

1
Q

most common cause of infectious urethritis

A

N. gonorrhoeae

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2
Q

most common common cause of non-infectious urethritis

A

chlamydia trachomatis, ureaplasma urealyticum

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3
Q

most common cause of non-infectious urethritis

A

reactive arthritis (Reiter syndrome)

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4
Q

[diagnosis]

inflamed granulation tissue covered with friable mucosa

may ulcerate and bleed

A

urethral caruncle

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5
Q

[diagnosis: penis]

abnormal opening on the ventral shaft of the penis

A

hypospadia

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6
Q

[[diagnosis]

abnormal opening on the dorsal shaft of the penis

A

epispadia

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7
Q

[diagnosis]

foreskin orifice too small to permit normal retraction; favors infection and CA

A

phimosis

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8
Q

[diagnosis]

infection of glans and prepuce

A

balanoposthitis

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9
Q

[diagnosis]

single, multiple, sessile, pedunculated, red papillary excrescences, noted koilocytosis, papillomatosis, acanthosis with irderly maturation and no atypia rarely progresses to cancer

A

condyloma acuminatum

HPV 6 and 11

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10
Q

[diagnosis]

associated with HPV 16, solitary, thickened, fgray-white, opaque plaque

shiny, red velvety plaque

Histo: dysplastic with large hyperchromatic nuclei, lack of orderly maturation, Basement membrane is intact

10% risk of penile SCCA

A

bowen disease

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11
Q

erythroplasia of queyrat is see in ____

A

bowen disease

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12
Q

[diagnosis]

associated with HPV 16, multiple, reddish-brown papules

Histo: dysplastic with large hyperchromatic nuclei, lack of orderly maturation, Basement membrane is intact

no risk of penile SCCA

A

bowenoid papulosis

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13
Q

most common site of location of testis in cryptochordhism

A

inguinal canal

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14
Q

most common phase of arrest in cryptochordism

A

inguinoscrotal

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15
Q

what month of gestation in which the testis descends the abdomen at the inguinoscrotal level

A

4th to 7th month AOG

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16
Q

gonorrhea and TB first affects this part of the male genital tract

A

epididymis

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17
Q

syphilis first affects this part of the male genital tract

A

testis

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18
Q

this part of the male genital tract is spared in syphilis infection

A

epididymis

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19
Q

tender mass with or without fever, painless mass (mimics testicular tumor), non-caseating granulomas in spermatic tubules

A

granulomatous orchitis

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20
Q

____ (tuberculous/non-tuberculous) diffuse caseating granulomas in testis confined to seminiferous tubules

A

tuberculous

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21
Q

[diagnosis]

post-pubertal males, unilateral, occurs a week after parotitis,

A

mumps orchitis

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22
Q

[diagnosis]

characteristics of mumps orchitis are not associated with infertility

A

unilateral, interstitial involvement, patchy and haphazard involvement

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23
Q

golden period in testicular torsion

A

6 hours

24
Q

___ deformity associated with increased mobility of testis

A

bell-clapper deformity

25
Q

most common cause of painless testicular enlargement

A

testicular tumor

26
Q

most common type of testicular tumor

A

germ cell tumor

27
Q

most common method of metastasis of testicular tumor is via lymphatic spread via the ____ nodes

A

retroperitoneal para-aortic nodes

28
Q

peak age of seminoma

A

3rd decade

29
Q

[diagnosis: testis]

large, polyhedral, with clear cytoplasm, central nuclei with one or two prominent nucleoli; moderate lymphatic infiltrate

CD117 (c-kit), PLAP (+), AFP (-)
(+) HCG

A

seminoma

30
Q

other term for yolk sac tumor

A

endodermal sinus tumor

infantile embryonal carcinoma

31
Q

[diagnosis]

patient 20-30 years old, extend through tunica albuginea and epididymis

gross: smaller than seminomas, poorly demarcated mass, punctuated with foci of hemorrhages
cytology: large, anaplastic cells with indistinct borders, tumor giant cells and frequent mitosis

CD30 (+) CD117 ckit (-)

A

embryonal carcinoma

32
Q

[diagnosis]

patient is <3 years old

gross: encapsulated, solid; homogenous, yellow-white, mucinous/gelatinous cut surface
cytology: lace-like, reticular network; medium-sized cuboidal or flattened cells

(+) AFP (highly charactestics)

A

yolk sac tumor

33
Q

[diagnosis]

schiller-Duval bodies/glomeruloid (50%), hyaline-like globules

(+) alpha 1 antitrypsin
(+) AFP

A

yolk sac tumor

34
Q

[diagnosis]
normal sized testis, small palpable nodule

(+) HCG

cyto: atypical cytotrophoblasts and syncitiotrophoblast without villi

A

choriocarcinoma

35
Q

[diagnosis]

complex tumor, more than 1 germ cell later

well-differentiated cells and organoid structures in a fibrous stroma

A

mature testicular teratoma

36
Q

[diagnosis]

second most common testicular tumor in infants and children

A

teratoma

37
Q

most common form of testicular neoplasm in men >60 years old

A

testicular lymphoma

38
Q

[diagnosis]

patient 20 years old, testicular swelling, gynecomastia, sexual precocity

cyto: well-differentiated polygonal cells with abundant granular cytoplasm

A

leydig cell tumor

produce androgen or estrogen

39
Q

[diagnosis]

crystalloids of reinke

A

leydig cell tumor

40
Q

[diagnosis]

patient 40 years old, testicular swelling, hormonally silent

cyto: trabeculae, cords resemble semineferous tubules

A

sertoli cel tumor

41
Q

most common site of prostatic epithelial neoplasia and cancer

A

peripheral zone

42
Q

most common site of nodular prostatic hyperplasia

A

transitional zone (inner periurethral)

43
Q

most common cancer in males

A

prostate cancer

44
Q

[diagnosis]

65 year old male with urinary obstruction, prostate is fibromuscular and glandular lcoated in the transitional zone

A

nodular prostatic hyperplasia

45
Q

[diagnosis]

fever, chills, dysuria, tender, boggy prostate

prostatic secretion: >15/HPF without pyuria

(+) cultrue

A

acute bacterial prostatitis

46
Q

[diagnosis]

fever, chills, dysuria, tender, boggy prostate

(+) E. coli on culture

prostatic secretion: >15/HPF without pyuria

A

chronic bacterial prostatitis

47
Q

most common cause of chronic abacterial prostatitis

A

C. trachomatis
M. hominis
Trachomonas
U. urealyticum

48
Q

[diagnosis]

(-) history of recurrent UTI
painful ejaculation
fever, chills, dysuria, tender, boggy prostate

prostatic secretion: >10/HPF
negative culture

A

chronic abacterial prostatitis

49
Q

[diagnosis]

dysuria, increased urinary frequency, complete urinary retention, hematuria, back or hip pain

PSA is not so elevated

A

prostatic adeno CA

50
Q

most common site of bone metastasis of prostatic CA

A

lumbar

51
Q

predominant lesion of bone metastasis from prostatic CA

A

blastic lesion

52
Q

PSA is synthesized by what cell of the prostate gland

A

epithelial cell

53
Q

normal PSA value range is ____

A

0-4 ng/mL

54
Q

If free PSA is high, what is the diagnosis

A

BPH

55
Q

if complex PSA is high, what is the diagnosis

A

CA

56
Q

in gleason scoring, positive for this status is associated with a fatals outcome regardless of T

A

nodal status

57
Q

in gleason scoring, the best prognostic factors includes

A

grade and stage

Pathology (36 decks)

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