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Pathology > Infectious Diseases > Flashcards

Infectious Diseases Flashcards

1
Q

infectious disease wherein the mononuclear response is primarily plasma cells

A

syphilis

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2
Q

Coplik spots
Cough
Coryza
Conjunctivitis

A

Rubeola (Measles)

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3
Q

Rash: face then spreads to the body, confluent

A

Rubeola (measles)

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4
Q

Forschmeir spots

A

rubella (german measles)

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5
Q

low grade fever, then rash, then lymphadenopathy at 2nd week

A

Rubella (german measles)

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6
Q

high grade fever then rash (neck to extremities)

A

roseola (HHV 6)

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7
Q

dewdrops on a rose petal

A

VZV

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8
Q

(-) monospot test
large cells with atypia
intranuclear basophilic inclusions

A

CMV

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9
Q

virus associated with paracortical hyperplasia of LN

-) heterophile test (monospot

A

EBV = HHV 4

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10
Q

gram +, rod, non motile, non spore forming, (+) coagulated exudate with marked vascular congestion, interstitial edema, fibrin exudation

A

C. diphtheriae

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11
Q

facultative non-aerobe
G+, non-spore forming, motile rod, catalase positive, oxidase negative, beta hemolytic

causes granulomatosis infantiseptica

A

L. monocytogenes

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12
Q

Steeple sign, croup, mucousal erosion, hyperemia, copious mucopurulent exudate

A

Bordetella

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13
Q

pale necrotic centers with red hemorrhagic periphery, causes coagulative necrosis due to vasculitis, perivascurlar blue haze

A

pseudomonas

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14
Q

painful with shaggy non-indurated border with yellow-gray at base (genitalia), prominent buboes.

What is the causative agent?

A

Haemophilus ducreyi

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15
Q

beefy red ulcer with indurated borders which can lead to strictures (genitals); not prominent LN,

giemsa/Warthin-starry stain

A

Klebsiella granulomatis

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16
Q

[TB]

Ghon focus is usually found in which specific part of the lung

A
  1. Subpleural
  2. lower part of upper lobe
  3. upper part of lower lobe
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17
Q

[TB]

simmon focus is located in which specific part of the lung

A
  1. apex
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18
Q

[TB]

Ghon focus with pulmonary hilar involvement. What is this called

A

ranke complex

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19
Q

[TB]
TB spreads to adjacent parenchyma, erosions into bronchi or vessels resulting to effusions, empyema, obliterative fibrous pleuritis

A

miliary TB

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20
Q

most common form of extrapulmonary TB

A

scrofula

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21
Q

[TB]

macrophages filled with acid-fast bacilli but with rare granuloma formation

A

mycobacterium avium intracellulare

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22
Q

[TB]
Type of leprosy wherein there is a predominance of TH2, depressed CMI, and antibodies are not protective (causes GN and vasculitis)

A

lepromatous

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23
Q

[leprosy]

lepromin test positive is ____ type of leprosy

A

tuberculoid

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24
Q

[leprosy]

lipid-laden macrophages with globi is pahtognomonic of what type of leprosy

A

lepromatous

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25
Q

[stage of syphilis]

plasma cell rich infiltrate, proliferative endarteritis, dominance of macrophages, lymphocytes

A

primary stage

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26
Q

[stage of syphilis]

lesser inflammation, mucocutaenous involvement

A

secondary stage

27
Q

[stage of syphilis]

central coagulation necrosis, surrounded by palisading macrophages and fibroblast, few treponemes

A

Tertiary state

28
Q

[stage of syphilis]

obliterative endarteritis of vasa vasorum leading to loss of elasticity

A

tertiary stage

29
Q

[congenital syphilis]

in saddle nose deformity, what bone is destroyed

A

vomer

30
Q

[congenital syphilis]

triad of late manifestation of congenital syphilis

A

interstitial keratitis
hutchinson teeth
eight nerve deafness

31
Q

[STD]

Test tubes in a rack appearance with papillary dermal edema. What is the causative agent

A

T. pallidum

32
Q

[STD]

papillary fronds covered with hyperplastic squamous epithelium. This is due to?

A

HPV 6, 11

33
Q

[Syphilis]

RPR and VDRL are good screening test for syphilis. these are (treponemal/non-treponemal tests)?

A

non-treponemal

34
Q

[syphilis]

RPR and VDRL detects ___ antibodies

A

anti-cardiolipin antibodies

35
Q

[syphilis]

Anti T. pallidum antibodies are detected by this test

A

FTA-ABS
MHA-TP
TPPA

36
Q

[syphilis]
___ phenomenon wherein there are too many antibodies preventing antibody-antigen complex thus there is no flocculation resulting to a false negative result

A

prozone phenomenon

37
Q

Cite all 7 pyogenic bacteria

A
  1. S. aureus (aw)
  2. S. epidermidis (strip)
  3. S. pyogenes (strip)
  4. S. pneumoniae (strip)
  5. P. aeruginosa (P)
  6. E. coli (E)
  7. K. pneumoniae (K)

Aw, strip PEK

38
Q

[anaerobes]

alpha toxin (lecithinase)

A

C. perfringes

39
Q

[anaerobes]
Toxin A: chemokine
Toxin B: cytotoxin

A

C. difficile

40
Q

[Anaerobes]

Mucopurulent exudate reminiscent of a volcano

A

C. difficile

41
Q

[STD]

purulent, abacterial urtethritis

A

chlamydia trichomatis

42
Q

[STD]

strain of chlamydia that causes inclusion cells and stellate abscesses in LN

A

L strains

43
Q

[fungal]

predominant hyphae form of candida albicans, seen in ICCs

A

pseudohyphae

44
Q

[fungal]

yeast, PAS positive, mucicarmine positive, prominent polysaccharide capsule

A

cryptococcus neoformans

45
Q

[fungal]

soap bubble lesion

A

cryptococcus neoformans

46
Q

[fungal]

septate, branching at 40 degree angle, necrotizing pneumonia

A

aspergillus

47
Q

[fungal]

non-septate, branching at 90 degree angle, hemorrhagic pneumonia

A

mucor

48
Q

[para]

asexual stages of parasite with hemozoin

A

plasmodium spp

49
Q

[para]

asexual states of parasite without hemozoin

A

babesia spp

50
Q

[para]

durck granulomas (perivascular ring hemorrhages)

A

cerebral malaria

51
Q

[para]

chancre at bite site,parasite in capillary loops (choroid plexus, glomeruli)

A

african trypanosomiasis

52
Q

[para]

demyelinating panencephalitis

A

african trypanosomiasis

53
Q

[para]

dilated CMP
megacolon
megaesophagus

A

T. cruzi

54
Q

[para]

no organism in ganglia of aurbach plexus but noted megacolon

A

T. cruzi

55
Q

[metazoans]
encyst in striated muscles resulting to loss of striations, formation of collagenous capsule, development of new blood vessels

A

Trichnella spiralis

56
Q

[metazoans]

larvae in duodenal crypts, with eosinophil-rich infiltrate, in lamina propria, mucosal edema, hyperinfection

A

Strongyloides stercoralis

57
Q

[metazoans]

result to thickening of tunica vaginalis

A

B. malayi

W. bancrofti

58
Q

[metazoans]

Meyers-kouwenaar bodies

A

B. malayi

W. bancrofti

59
Q

[metazoans]

vector is: simulium spp

A

Onchocerca volvulus

60
Q

[metazoans]
epidermal atrophy and elastic fiber breakdown alternating with hyperkeratosis, hyperpigmentation with pigment incontinence

A

Onchocerca volvulus

61
Q

[trematodes]

pipestem fibrosis

A

S. japonicum

S. masoni

62
Q

[trematodes]

ovoid, white to opalescent, grape-shaped, has invaginated scolex bathed with clear cyst fluid

A

Taenia solinum

63
Q

[trematodes]

cyst with inner germinative and outer non-germinative layer with surrounding fibrosis, noted degenerating scolices

A

Echinococcus granulosus

64
Q

___ accentuation of keratitits with anti-filarial treatment

A

Mazzoti reaction

Pathology (36 decks)

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