Infectious Diseases

Question 1

infectious disease wherein the mononuclear response is primarily plasma cells

Answer 1

syphilis

Question 2

Coplik spots
Cough
Coryza
Conjunctivitis

Answer 2

Rubeola (Measles)

Question 3

Rash: face then spreads to the body, confluent

Answer 3

Rubeola (measles)

Question 4

Forschmeir spots

Answer 4

rubella (german measles)

Question 5

low grade fever, then rash, then lymphadenopathy at 2nd week

Answer 5

Rubella (german measles)

Question 6

high grade fever then rash (neck to extremities)

Answer 6

roseola (HHV 6)

Question 7

dewdrops on a rose petal

Answer 7

VZV

Question 8

(-) monospot test
large cells with atypia
intranuclear basophilic inclusions

Answer 8

CMV

Question 9

virus associated with paracortical hyperplasia of LN

-) heterophile test (monospot

Answer 9

EBV = HHV 4

Question 10

gram +, rod, non motile, non spore forming, (+) coagulated exudate with marked vascular congestion, interstitial edema, fibrin exudation

Answer 10

C. diphtheriae

Question 11

facultative non-aerobe
G+, non-spore forming, motile rod, catalase positive, oxidase negative, beta hemolytic

causes granulomatosis infantiseptica

Answer 11

L. monocytogenes

Question 12

Steeple sign, croup, mucousal erosion, hyperemia, copious mucopurulent exudate

Answer 12

Bordetella

Question 13

pale necrotic centers with red hemorrhagic periphery, causes coagulative necrosis due to vasculitis, perivascurlar blue haze

Answer 13

pseudomonas

Question 14

painful with shaggy non-indurated border with yellow-gray at base (genitalia), prominent buboes.

What is the causative agent?

Answer 14

Haemophilus ducreyi

Question 15

beefy red ulcer with indurated borders which can lead to strictures (genitals); not prominent LN,

giemsa/Warthin-starry stain

Answer 15

Klebsiella granulomatis

Question 16

[TB]

Ghon focus is usually found in which specific part of the lung

Answer 16

1. Subpleural
2. lower part of upper lobe
3. upper part of lower lobe

Question 17

[TB]

simmon focus is located in which specific part of the lung

Answer 17

1. apex

Question 18

[TB]

Ghon focus with pulmonary hilar involvement. What is this called

Answer 18

ranke complex

Question 19

[TB]
TB spreads to adjacent parenchyma, erosions into bronchi or vessels resulting to effusions, empyema, obliterative fibrous pleuritis

Answer 19

miliary TB

Question 20

most common form of extrapulmonary TB

Answer 20

scrofula

Question 21

[TB]

macrophages filled with acid-fast bacilli but with rare granuloma formation

Answer 21

mycobacterium avium intracellulare

Question 22

[TB]
Type of leprosy wherein there is a predominance of TH2, depressed CMI, and antibodies are not protective (causes GN and vasculitis)

Answer 22

lepromatous

Question 23

[leprosy]

lepromin test positive is ____ type of leprosy

Answer 23

tuberculoid

Question 24

[leprosy]

lipid-laden macrophages with globi is pahtognomonic of what type of leprosy

Answer 24

lepromatous

Question 25

[stage of syphilis] plasma cell rich infiltrate, proliferative endarteritis, dominance of macrophages, lymphocytes

Answer 25

primary stage

Question 26

[stage of syphilis] lesser inflammation, mucocutaenous involvement

Answer 26

secondary stage

Question 27

[stage of syphilis] central coagulation necrosis, surrounded by palisading macrophages and fibroblast, few treponemes

Answer 27

Tertiary state

Question 28

[stage of syphilis] | obliterative endarteritis of vasa vasorum leading to loss of elasticity

Answer 28

tertiary stage

Question 29

[congenital syphilis] in saddle nose deformity, what bone is destroyed

Answer 29

vomer

Question 30

[congenital syphilis] triad of late manifestation of congenital syphilis

Answer 30

interstitial keratitis hutchinson teeth eight nerve deafness

Question 31

[STD] Test tubes in a rack appearance with papillary dermal edema. What is the causative agent

Answer 31

T. pallidum

Question 32

[STD] papillary fronds covered with hyperplastic squamous epithelium. This is due to?

Answer 32

HPV 6, 11

Question 33

[Syphilis] RPR and VDRL are good screening test for syphilis. these are (treponemal/non-treponemal tests)?

Answer 33

non-treponemal

Question 34

[syphilis] RPR and VDRL detects ___ antibodies

Answer 34

anti-cardiolipin antibodies

Question 35

[syphilis] Anti T. pallidum antibodies are detected by this test

Answer 35

FTA-ABS MHA-TP TPPA

Question 36

[syphilis] ___ phenomenon wherein there are too many antibodies preventing antibody-antigen complex thus there is no flocculation resulting to a false negative result

Answer 36

prozone phenomenon

Question 37

Cite all 7 pyogenic bacteria

Answer 37

1. S. aureus (aw) 2. S. epidermidis (strip) 3. S. pyogenes (strip) 4. S. pneumoniae (strip) 5. P. aeruginosa (P) 6. E. coli (E) 7. K. pneumoniae (K) Aw, strip PEK

Question 38

[anaerobes] alpha toxin (lecithinase)

Answer 38

C. perfringes

Question 39

[anaerobes] Toxin A: chemokine Toxin B: cytotoxin

Answer 39

C. difficile

Question 40

[Anaerobes] Mucopurulent exudate reminiscent of a volcano

Answer 40

C. difficile

Question 41

[STD] purulent, abacterial urtethritis

Answer 41

chlamydia trichomatis

Question 42

[STD] strain of chlamydia that causes inclusion cells and stellate abscesses in LN

Answer 42

L strains

Question 43

[fungal] predominant hyphae form of candida albicans, seen in ICCs

Answer 43

pseudohyphae

Question 44

[fungal] yeast, PAS positive, mucicarmine positive, prominent polysaccharide capsule

Answer 44

cryptococcus neoformans

Question 45

[fungal] soap bubble lesion

Answer 45

cryptococcus neoformans

Question 46

[fungal] | septate, branching at 40 degree angle, necrotizing pneumonia

Answer 46

aspergillus

Question 47

[fungal] non-septate, branching at 90 degree angle, hemorrhagic pneumonia

Answer 47

mucor

Question 48

[para] asexual stages of parasite with hemozoin

Answer 48

plasmodium spp

Question 49

[para] | asexual states of parasite without hemozoin

Answer 49

babesia spp

Question 50

[para] durck granulomas (perivascular ring hemorrhages)

Answer 50

cerebral malaria

Question 51

[para] chancre at bite site,parasite in capillary loops (choroid plexus, glomeruli)

Answer 51

african trypanosomiasis

Question 52

[para] | demyelinating panencephalitis

Answer 52

african trypanosomiasis

Question 53

[para] dilated CMP megacolon megaesophagus

Answer 53

T. cruzi

Question 54

[para] no organism in ganglia of aurbach plexus but noted megacolon

Answer 54

T. cruzi

Question 55

[metazoans] encyst in striated muscles resulting to loss of striations, formation of collagenous capsule, development of new blood vessels

Answer 55

Trichnella spiralis

Question 56

[metazoans] larvae in duodenal crypts, with eosinophil-rich infiltrate, in lamina propria, mucosal edema, hyperinfection

Answer 56

Strongyloides stercoralis

Question 57

[metazoans] result to thickening of tunica vaginalis

Answer 57

B. malayi | W. bancrofti

Question 58

[metazoans] Meyers-kouwenaar bodies

Answer 58

B. malayi | W. bancrofti

Question 59

[metazoans] vector is: simulium spp

Answer 59

Onchocerca volvulus

Question 60

[metazoans] epidermal atrophy and elastic fiber breakdown alternating with hyperkeratosis, hyperpigmentation with pigment incontinence

Answer 60

Onchocerca volvulus

Question 61

[trematodes] pipestem fibrosis

Answer 61

S. japonicum | S. masoni

Question 62

[trematodes] ovoid, white to opalescent, grape-shaped, has invaginated scolex bathed with clear cyst fluid

Answer 62

Taenia solinum

Question 63

[trematodes] cyst with inner germinative and outer non-germinative layer with surrounding fibrosis, noted degenerating scolices

Answer 63

Echinococcus granulosus

Question 64

___ accentuation of keratitits with anti-filarial treatment

Answer 64

Mazzoti reaction