Infectious Diseases Flashcards
infectious disease wherein the mononuclear response is primarily plasma cells
syphilis
Coplik spots
Cough
Coryza
Conjunctivitis
Rubeola (Measles)
Rash: face then spreads to the body, confluent
Rubeola (measles)
Forschmeir spots
rubella (german measles)
low grade fever, then rash, then lymphadenopathy at 2nd week
Rubella (german measles)
high grade fever then rash (neck to extremities)
roseola (HHV 6)
dewdrops on a rose petal
VZV
(-) monospot test
large cells with atypia
intranuclear basophilic inclusions
CMV
virus associated with paracortical hyperplasia of LN
-) heterophile test (monospot
EBV = HHV 4
gram +, rod, non motile, non spore forming, (+) coagulated exudate with marked vascular congestion, interstitial edema, fibrin exudation
C. diphtheriae
facultative non-aerobe
G+, non-spore forming, motile rod, catalase positive, oxidase negative, beta hemolytic
causes granulomatosis infantiseptica
L. monocytogenes
Steeple sign, croup, mucousal erosion, hyperemia, copious mucopurulent exudate
Bordetella
pale necrotic centers with red hemorrhagic periphery, causes coagulative necrosis due to vasculitis, perivascurlar blue haze
pseudomonas
painful with shaggy non-indurated border with yellow-gray at base (genitalia), prominent buboes.
What is the causative agent?
Haemophilus ducreyi
beefy red ulcer with indurated borders which can lead to strictures (genitals); not prominent LN,
giemsa/Warthin-starry stain
Klebsiella granulomatis
[TB]
Ghon focus is usually found in which specific part of the lung
- Subpleural
- lower part of upper lobe
- upper part of lower lobe
[TB]
simmon focus is located in which specific part of the lung
- apex
[TB]
Ghon focus with pulmonary hilar involvement. What is this called
ranke complex
[TB]
TB spreads to adjacent parenchyma, erosions into bronchi or vessels resulting to effusions, empyema, obliterative fibrous pleuritis
miliary TB
most common form of extrapulmonary TB
scrofula
[TB]
macrophages filled with acid-fast bacilli but with rare granuloma formation
mycobacterium avium intracellulare
[TB]
Type of leprosy wherein there is a predominance of TH2, depressed CMI, and antibodies are not protective (causes GN and vasculitis)
lepromatous
[leprosy]
lepromin test positive is ____ type of leprosy
tuberculoid
[leprosy]
lipid-laden macrophages with globi is pahtognomonic of what type of leprosy
lepromatous
[stage of syphilis]
plasma cell rich infiltrate, proliferative endarteritis, dominance of macrophages, lymphocytes
primary stage
[stage of syphilis]
lesser inflammation, mucocutaenous involvement
secondary stage
[stage of syphilis]
central coagulation necrosis, surrounded by palisading macrophages and fibroblast, few treponemes
Tertiary state
[stage of syphilis]
obliterative endarteritis of vasa vasorum leading to loss of elasticity
tertiary stage
[congenital syphilis]
in saddle nose deformity, what bone is destroyed
vomer
[congenital syphilis]
triad of late manifestation of congenital syphilis
interstitial keratitis
hutchinson teeth
eight nerve deafness
[STD]
Test tubes in a rack appearance with papillary dermal edema. What is the causative agent
T. pallidum
[STD]
papillary fronds covered with hyperplastic squamous epithelium. This is due to?
HPV 6, 11
[Syphilis]
RPR and VDRL are good screening test for syphilis. these are (treponemal/non-treponemal tests)?
non-treponemal
[syphilis]
RPR and VDRL detects ___ antibodies
anti-cardiolipin antibodies
[syphilis]
Anti T. pallidum antibodies are detected by this test
FTA-ABS
MHA-TP
TPPA
[syphilis]
___ phenomenon wherein there are too many antibodies preventing antibody-antigen complex thus there is no flocculation resulting to a false negative result
prozone phenomenon
Cite all 7 pyogenic bacteria
- S. aureus (aw)
- S. epidermidis (strip)
- S. pyogenes (strip)
- S. pneumoniae (strip)
- P. aeruginosa (P)
- E. coli (E)
- K. pneumoniae (K)
Aw, strip PEK
[anaerobes]
alpha toxin (lecithinase)
C. perfringes
[anaerobes]
Toxin A: chemokine
Toxin B: cytotoxin
C. difficile
[Anaerobes]
Mucopurulent exudate reminiscent of a volcano
C. difficile
[STD]
purulent, abacterial urtethritis
chlamydia trichomatis
[STD]
strain of chlamydia that causes inclusion cells and stellate abscesses in LN
L strains
[fungal]
predominant hyphae form of candida albicans, seen in ICCs
pseudohyphae
[fungal]
yeast, PAS positive, mucicarmine positive, prominent polysaccharide capsule
cryptococcus neoformans
[fungal]
soap bubble lesion
cryptococcus neoformans
[fungal]
septate, branching at 40 degree angle, necrotizing pneumonia
aspergillus
[fungal]
non-septate, branching at 90 degree angle, hemorrhagic pneumonia
mucor
[para]
asexual stages of parasite with hemozoin
plasmodium spp
[para]
asexual states of parasite without hemozoin
babesia spp
[para]
durck granulomas (perivascular ring hemorrhages)
cerebral malaria
[para]
chancre at bite site,parasite in capillary loops (choroid plexus, glomeruli)
african trypanosomiasis
[para]
demyelinating panencephalitis
african trypanosomiasis
[para]
dilated CMP
megacolon
megaesophagus
T. cruzi
[para]
no organism in ganglia of aurbach plexus but noted megacolon
T. cruzi
[metazoans]
encyst in striated muscles resulting to loss of striations, formation of collagenous capsule, development of new blood vessels
Trichnella spiralis
[metazoans]
larvae in duodenal crypts, with eosinophil-rich infiltrate, in lamina propria, mucosal edema, hyperinfection
Strongyloides stercoralis
[metazoans]
result to thickening of tunica vaginalis
B. malayi
W. bancrofti
[metazoans]
Meyers-kouwenaar bodies
B. malayi
W. bancrofti
[metazoans]
vector is: simulium spp
Onchocerca volvulus
[metazoans]
epidermal atrophy and elastic fiber breakdown alternating with hyperkeratosis, hyperpigmentation with pigment incontinence
Onchocerca volvulus
[trematodes]
pipestem fibrosis
S. japonicum
S. masoni
[trematodes]
ovoid, white to opalescent, grape-shaped, has invaginated scolex bathed with clear cyst fluid
Taenia solinum
[trematodes]
cyst with inner germinative and outer non-germinative layer with surrounding fibrosis, noted degenerating scolices
Echinococcus granulosus
___ accentuation of keratitits with anti-filarial treatment
Mazzoti reaction
