Lecture 51 - Transmission Flashcards
infectivity
likelihood that an agent will cause infection
pathogenicity
ability of an agent to cause clinical disease
virulence
severity of illness the agent causes in the host
Host determinants of disease
- susceptibility
- immune response
Colonization
pathogen exists on/enters host but has not invaded tissue to cause infection
Infection
pathogen enters tissue of susceptible host
Carrier
host can transmit infection even if experiencing no symptoms
what are the transmission routes of disease-causing agents?
- aerosol
- oral
- fomite (inanimate objects)
- direct contact
- reproductively passed
- vector-borne
What factors influence transmission through a population?
- rate that infected hosts become infectious
- duration of infectiveness
Case fatality ratio
CFR = (# of deaths / # of confirmed cases) * 100
disease-specific mortality rate
deaths from disease / (# of individuals in the population * time)