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Animal Health & Disease 1 > Lecture 17 - Avian/Reptile Immunology > Flashcards

Lecture 17 - Avian/Reptile Immunology Flashcards

1
Q

What are some non-immunological differences between avians and mammals

A
  • no diaphragm
  • nucleated RBCs
  • choanal slit in palate
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2
Q

What are the primary lymph organs

A

bursa - B cells
thymus - T cells

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3
Q

What are the secondary lymph organs

A

spleen, GALT, BALT, harderian

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4
Q

what two immune organs allow for vaccination in eye drops for chickens

A

conjunctiva associated lymphoid tissue
harderian gland

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5
Q

What enzymes are absent in heterophils

A

myeloperoxidase
catalase

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6
Q

What do heterophils rely on for pathogen breakdown

A

oxygen-independent mechanisms

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7
Q

Where are dendritic cells found in the chicken

A

bursa, thymus, splenic follicles

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8
Q

What PRR is absent in chickens/turkeys

A

Rig-1-like receptor

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9
Q

What is the equivalent of TLR9 in humans for birds

A

TLR 15

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10
Q

What is the B complex

A

MHC complexes in birds

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11
Q

Give the molecules and location of:

MHCI

A

B-F; all cells

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12
Q

Give the molecules and location of:

MHCII

A

B-L; APCs

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13
Q

Give the molecules and location of:

MHC IV

A

B-G; RBCs

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14
Q

T/F: the chicken MHC has a strong association with disease resistance and susceptibility

A

True

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15
Q

How many class 1 molecules are present in the chicken? how many are present in humans?

A

2; 6

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16
Q

What disease is the best example for illustrating the link between B complexes and susceptibility

A

Marek’s disease

17
Q

What is the site of B cell education and programming

A

bursa of Fabricius

18
Q

What immunoglobulin is predominant in primary response

A

IgM

19
Q

What immunoglobulin is predominant in secondary response

A

IgG/IgY

20
Q

What immunoglobulin is predominant in body fluids

A

IgA

21
Q

Where do neonates receive each immunoglobulin in passive immunity

A

IgG/IgY - yolk sac
IgA/IgM - oviduct secretions (amniotic)

22
Q

What does IEL standard for

A

Intra-epithelial lymphocytes

23
Q

Where is IEL found

A

between the cells of the intestinal lining

24
Q

What important structure is absent in reptiles

A

germinal centers

25
Q

T/F: The structure of the reptilian thymus and spleen are the same at all times

A

False - seasonal variation affects leukocyte distribution

26
Q

What are ILF and what do they function as in reptiles

A

Isolated lymphoid follicle-like
act as lymphoid structures for B/T cells

27
Q

What two immunoglobulin isotypes are present in reptiles

A

IgM and IgY

Animal Health & Disease 1 (52 decks)

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