Introduction to pharmacology

Question 1

what organization controls prescription drugs?

Answer 1

FDA

Question 2

what organizations control who can sell prescription drugs?

Answer 2

state legislatures

Question 3

what are the features of a schedule I drug?

Answer 3

1. high abuse potential
2. no medical use

example: heroin

Question 4

what are the features of a schedule II drug?

Answer 4

1. high abuse potential
2. no medical use
3. potential for psychological and physical dependence

example: morphine

Question 5

what are the features of a schedule III drug?

Answer 5

1. medical use
2. low potential for physical dependence
3. high potential for psychological dependence

example: anabolic steroids

Question 6

what are the features of a schedule IV drug?

Answer 6

1. medical use
2. little potential for dependence

example: phenobarbitol

Question 7

what are the features of a schedule V drug?

Answer 7

1. medical use
2. limited dependence

example: buprenorphine

Question 8

which organization monitors OTCs?

Answer 8

Nonprescription Drug Advisory Committee of the USDA

Question 9

what characterizes phase I drug development?

Answer 9

limits safe dose range (LD)

Question 10

what characterizes phase II drug development?

Answer 10

finding out if it works

Question 11

what characterizes phase III drug development?

Answer 11

well controlled, larger sample size

Question 12

what characterizes phase IV drug development?

Answer 12

post-marketing surveillance, monitor during clinical use by FDA

Question 13

definition: pharmacokinetics

Answer 13

drug action in the body - absorption, distribution, metabolism, elimination - “what is the body doing to the drug?”

Question 14

definition: pharmacodynamics

Answer 14

how a drug produces an effect - targets / receptors, signal transduction, physiological / therapeutic effects - “what is the drug doing to the body?”