Antibiotics III Flashcards
what are good choices for uncomplicated skin and soft tissue infections? what if there is an allergy to these?
penicillins (ampicillin)
1st generation cephalosporin (cephalexin)
if allergy - vancomycin, clindamycin
what are good choices for complicated skin and soft tissue infections?
penicillin plus lactamase inhibitor
broader spectrum
what three major agents are used against MRSA?
vancomycin
linezolid
daptomycin
what are the empiric agents for osteomyelitis?
vancomycin
cephalosporins (ceftriaxone, cefepime)
what general class of abx drugs is used against bone and joint infections?
cell wall inhibitors
what agents are used for bone and joint infections following surgery?
penicillin plus lactamase inhibitor
what agent is used as empiric treatment of septic arthritis?
ceftriaxone
what agents are used for MRSA in septic arthritis?
vancomycin
linezolid
daptomycin
what agents are used for acute sinusitis?
amoxicillin plus clavulanate
what agents are used for pharyngitis in upper respiratory tract infections?
penicillin or amoxicillin
with penicillin, can be more confident of gram positivity
what agents are used for ambulatory bacterial pneumonia? what is the reason for this?
macrolides
erythromycin
azithromycin
clarithromycin
m. pneumoniae does not have a cell wall - do not use agents that target cell walls
what agents are used for hospital acquired bacterial pneumonia?
beta lactam plus macrolide
what agents are used for MRSA complicated bacterial pneumonia?
vancomycin
linezolid
what is the big difference between s. pneumoniae and mycoplasma pneumoniae?
mycoplasma pneumoniae does not have peptidoglycan, thus beta lactams will not work
what agents are used for uncomplicated UTI - cystitis?
trimethoprim - sulfamethoxazole
