ID 8 Flashcards
How does elementary body of chlamydia enter cell?
endocytosed
chlamydia life cycle
elementary body enfects cell –> endocytose –> reticulate body replicates by fission –> reorganizes into elementary bodies
ophtho presentation of chlamydia
follicular conjunctivitis, which can lead to blindness
chlamdyophilia pneumonia and psittaci transmission
aerosol
characteristic finding with chlamydia neonatal pneumonia
staccato cough + eosinophilia
STD caused by chlamydia
lymphogranuloma venereum
serotypes that cause lymphogranuloma venereum?
L1,L2,L3
treatment options for mycoplasma
1) macrolides
2) doxycycline
3) fluoroquinolone
mycoplasma structure
pleomorphic
dimorphic fungi characteristics and exception
Cold (20C) = mold
heat (37C) = yeast
*coccidoido spherule, not yeast in tissue
treatment for systemic mycosis
local infection = fluconazole or itroconazole
systemic infection = amphotericin B
systemic mycoses contagious?
no
systemic mycoses can form granulomas
ok
blastomycosis location
eastern US + central america
blastomycosis on pathology
broad-base budding (blasto buds broadly)
blastomycosis histology
granulomatous nodules
blastomycosis presentation
inflammatory lung disease that can disseminate to skin and bone
characteristic coccidoido path
spherules filled with endospores
other name for coccidoido arthralgias
desert rheumatism
other name for coccidoido erythema nodosum
desert bumps
other name for coccidoido
San Joaquin Valley fever
tinea presentation
branching septet hyphae on KOH preparation with blue fungal stain
tine capitis associations
1) lymphadenopathy
2) alopecia
3) scaling
tinea corporis findings..
1) scaling rings (ringworm)
2) central clearing
tinea corporis sources
infected cat or dog
rash in inguinal area without central clearing think…
tinea cruris
tinea unguium
onychomychosis; occurs on nails
dermatophytes
microsporum
trichophyton
epidermophyton
malassezia organism type
yeast-like fungus
malassezia pathohpys
degradation of lipids –> acid production –> damaged to melanocytes –> hypo pigmented patches
tinea versicolor treatment
selenium sulfide, topical and/or oral antifungals
other name for tinea versicolor
pityriasis versicolor
candida form
dimorphic; pseudohyphae and budding yeast at 20C, germ tubes at 37 C
cause of diaper rash?
candida
treatment options for systemic canddia
1) fluconazole
2) caspofungin
3) amphotericin
ABPA findings
bronchiectasis
eosinophilia
cryptococcus description
5-10 micrometer with narrow budding. heavily encapsulated.
what does latex agglutination test?
polysaccharide capsular antigen
classic finding in cryptococcal encephalitis?
soap bubble lesions in brain
nucor and rhizupus structure
Irregular, broad, nonseptate hyphae branching at wide angles.
RF’s for mucor
1) diabetes
2) neutropenic
mucor route of infection
Proliferate in blood vessel walls –> penetrate cribriform plate –> enter brain.
mucor sequelae
1) rhino cerebral abscesses
2) frontal lobe abscess
3) cavernous sinus thrombosis
CXR finding with pneumocystis
Diffuse, bilateral ground-glass opacities.
how do you diagnose pneumocystis?
lung biopsy or lavage
when do you start prophylaxis with pneumocystis?
below 200
prophylaxis for pneumocystis?
dapsone
sporothrix description
cigar-snapped budding yeast that grows in branching hyphae with rosettes of conidia
term for presentation of sporothrix
ascending lymphangitis
