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STEP > ID 8 > Flashcards

ID 8 Flashcards

1
Q

How does elementary body of chlamydia enter cell?

A

endocytosed

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2
Q

chlamydia life cycle

A

elementary body enfects cell –> endocytose –> reticulate body replicates by fission –> reorganizes into elementary bodies

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3
Q

ophtho presentation of chlamydia

A

follicular conjunctivitis, which can lead to blindness

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4
Q

chlamdyophilia pneumonia and psittaci transmission

A

aerosol

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5
Q

characteristic finding with chlamydia neonatal pneumonia

A

staccato cough + eosinophilia

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6
Q

STD caused by chlamydia

A

lymphogranuloma venereum

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7
Q

serotypes that cause lymphogranuloma venereum?

A

L1,L2,L3

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8
Q

treatment options for mycoplasma

A

1) macrolides
2) doxycycline
3) fluoroquinolone

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9
Q

mycoplasma structure

A

pleomorphic

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10
Q

dimorphic fungi characteristics and exception

A

Cold (20C) = mold
heat (37C) = yeast
*coccidoido spherule, not yeast in tissue

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11
Q

treatment for systemic mycosis

A

local infection = fluconazole or itroconazole

systemic infection = amphotericin B

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12
Q

systemic mycoses contagious?

A

no

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13
Q

systemic mycoses can form granulomas

A

ok

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14
Q

blastomycosis location

A

eastern US + central america

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15
Q

blastomycosis on pathology

A

broad-base budding (blasto buds broadly)

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16
Q

blastomycosis histology

A

granulomatous nodules

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17
Q

blastomycosis presentation

A

inflammatory lung disease that can disseminate to skin and bone

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18
Q

characteristic coccidoido path

A

spherules filled with endospores

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19
Q

other name for coccidoido arthralgias

A

desert rheumatism

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20
Q

other name for coccidoido erythema nodosum

A

desert bumps

21
Q

other name for coccidoido

A

San Joaquin Valley fever

22
Q

tinea presentation

A

branching septet hyphae on KOH preparation with blue fungal stain

23
Q

tine capitis associations

A

1) lymphadenopathy
2) alopecia
3) scaling

24
Q

tinea corporis findings..

A

1) scaling rings (ringworm)

2) central clearing

25
Q

tinea corporis sources

A

infected cat or dog

26
Q

rash in inguinal area without central clearing think…

A

tinea cruris

27
Q

tinea unguium

A

onychomychosis; occurs on nails

28
Q

dermatophytes

A

microsporum
trichophyton
epidermophyton

29
Q

malassezia organism type

A

yeast-like fungus

30
Q

malassezia pathohpys

A

degradation of lipids –> acid production –> damaged to melanocytes –> hypo pigmented patches

31
Q

tinea versicolor treatment

A

selenium sulfide, topical and/or oral antifungals

32
Q

other name for tinea versicolor

A

pityriasis versicolor

33
Q

candida form

A

dimorphic; pseudohyphae and budding yeast at 20C, germ tubes at 37 C

34
Q

cause of diaper rash?

35
Q

treatment options for systemic canddia

A

1) fluconazole
2) caspofungin
3) amphotericin

36
Q

ABPA findings

A

bronchiectasis

eosinophilia

37
Q

cryptococcus description

A

5-10 micrometer with narrow budding. heavily encapsulated.

38
Q

what does latex agglutination test?

A

polysaccharide capsular antigen

39
Q

classic finding in cryptococcal encephalitis?

A

soap bubble lesions in brain

40
Q

nucor and rhizupus structure

A

Irregular, broad, nonseptate hyphae branching at wide angles.

41
Q

RF’s for mucor

A

1) diabetes

2) neutropenic

42
Q

mucor route of infection

A

Proliferate in blood vessel walls –> penetrate cribriform plate –> enter brain.

43
Q

mucor sequelae

A

1) rhino cerebral abscesses
2) frontal lobe abscess
3) cavernous sinus thrombosis

44
Q

CXR finding with pneumocystis

A

Diffuse, bilateral ground-glass opacities.

45
Q

how do you diagnose pneumocystis?

A

lung biopsy or lavage

46
Q

when do you start prophylaxis with pneumocystis?

47
Q

prophylaxis for pneumocystis?

48
Q

sporothrix description

A

cigar-snapped budding yeast that grows in branching hyphae with rosettes of conidia

49
Q

term for presentation of sporothrix

A

ascending lymphangitis

STEP (85 decks)

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