ID 10 Flashcards

1
Q

what causes intestinal tapeworm from taenia as opposed to cysticercosis/neurocysticercosis?

A

Ingestion of larvae, ingestion of eggs causes cysticercosis.

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2
Q

treatment for intestinal tapeworm (taenia solium)

A

praziquantel

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3
Q

treatment for cysticercosis/neurocysticercosis

A

cysticercosis –> praziquantel

neurocysticercosis –> albendazole

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4
Q

how do you prevent echinococcus related anaphylaxis?

A

Inject cyst with ethanol or hypertonic saline to kill daughter cysts before removal.

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5
Q

Echinococcus transmission

A

Ingestion of eggs from dog feces. Sheep are an intermediate host.

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6
Q

trematode?

A

fluke

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7
Q

what are the trematodes?

A

1) schistosoma

2) clonorchis sinensis

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8
Q

schisto presentation

A

liver + spleen enlargement + fibrosis + inflammation

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9
Q

what part of schisto life cycle penetrates humans?

A

cercariae

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10
Q

How do you differentiate S mansoni from s haemotobium?

A

S mansoni = egg with lateral spine.

S haematobium = egg with terminal spine

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11
Q

other complication of s haematobium?

A

pulmonary HTN

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12
Q

clonorchis sinensis causes

A

1) biliary tract inflammation –> pigmented gallstones

2) cholangiocarcinoma

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13
Q

parasite associated with brain cysts, seizures

A

taenia solium

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14
Q

parasites associated with portal HTN

A

1) schistosoma mansoni

2) schistosoma japonicum

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15
Q

what are scabies?

A

mites

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16
Q

scabies presentation

A

serpiginous burrows (lines) in webspace of hands and feet.

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17
Q

scabies pathophys

A

mites that burrow into the stratum corneum and cause pruritus

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18
Q

scabies transmission

A

fomites

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19
Q

where are scabies common?

A

children, crowded populations (jails, nursing homes)

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20
Q

scabies treatment

A

1) permethrin cream
2) wash/dry all clothing/bedding
3) treat close contacts

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21
Q

terms for lice

A

pediculus humanus

phthirus pubis

22
Q

lice presentation

A

intense pruritus + pink macule and papule in intertriginous areas

23
Q

organisms transmitted by lice

A

1) rickettsia prowazekii
2) borrelia recurrentis
3) bartonella quintana (trench fever)

24
Q

lice treatment

A

1) pyrethroids
2) malathion
3) ivermectin lotion
4) nit combing

25
what is complementation?
1 of 2 viruses that infects a cell has a mutation that results in a nonfunctional protein and the non mutated virus complements the mutated one by making a functional protein that serves both viruses.
26
classic example of complementation
hep D (needs HBsAg, the envelope protein for HDV)
27
phenotypic mixing
genome of virus A coated with surface proteins of virus B
28
nice thing about live attenuated vaccines..
don't need a booster
29
Only live attenuated vaccine you can give to immunocompetent HIV patients?
MMR
30
subunit vaccines
1) HBV (antigen = HBsAG) | 2) HPV (6,11,16, and 18)
31
only ssDNA DNA virus?
Parvoiridae
32
circular DNA viruses?
1) papilloma 2) polyoma 3) hepadnavirus
33
only RNA virus that isn't ss?
Reoviridae
34
positive sense RNA viruses?
1) retrovirus 2) togavirus 3) flavivirus 4) coronavirus 5) hepevirus 6) calicivirus 7) picornavirus
35
which virus particles are infectious
infectious: 1) nucleic acids of most dsDNA (except poxviruses and HBV) 2) positive sense strand ssRNA (basically mRNA) noninfectious: 1) naked nucleic acids of negative sense strand ssRNA and dsRNA viruses (require polymerases contained in complete virion).
36
DNA virus that replicates in the nucleus..
poxvirus
37
RNA virus that replicates in the nucleus
1) influenza | 2) *retroviruses
38
How do enveloped viruses acquire their envelopes? exception?
from plasma membrane when exiting except (herpesviruses (from nuclear membrane))
39
capsid rule with DNA viruses
all are icosahedral (except pox (complex)
40
how can pox virus replicate in the cytoplasm?
carries own DNA-dependent RNA polymerase
41
largest DNA virus
poxvirus
42
milkmaid blisters
cowpox
43
hepadnavirus structure
ENVELOPED partially DS and circular *has reverse transcriptase
44
adenovirus causes
1) febrile pharyngitis 2) acute hemorrhagic cystitis 3) pneumonia 4) conjunctivitis (pink eye)
45
CIN?
Cervical intraepithelial neoplasia. | Potentially premalignant transformation and abnormal growth (dysplasia) of squamous cells on the surface of the cervix.
46
HPV serotypes associated with warts?
1,2,6,11
47
what are the polyomaviruses?
1) JC virus | 2) BK virus
48
BK virus significance
transplant patients, commonly targets kidney. DS and circular
49
parvovirus structure
SS and linear
50
smallest DNA virus?
parvovirus