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STEP > ID 11 > Flashcards

ID 11 Flashcards

1
Q

HSV-1 route of transmission

A

respiratory secretions, saliva

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2
Q

HSV-1 causes…

A

1) gingivostomatitis
2) keratoconjunctivitis
3) herpes labials
4) herpetic whitlow
5) encephalitis

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3
Q

most common cause of sporadic encephalitis?

A

HSV-1

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4
Q

HSV-1 encephalitis presentation?

A

altered mental status + seizures + and/or aphasia

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5
Q

neonatal herpes caused by?

A

HSV-2

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6
Q

more common HSV causing viral meningitis?

A

HSV-2

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7
Q

VZV also known as

A

HHV-3

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8
Q

VZV can also cause

A

1) encephalitis

2) pneumonia

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9
Q

where does VZV establish latency?

A

dorsal root or trigeminal ganglia

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10
Q

EBV also known as..

A

HHV-4, herpes virus

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11
Q

EBV transmitted through

A

respiratory secretions, saliva

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12
Q

most common lymphadenopathy location for mono

A

posterior cervical nodes

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13
Q

CMV also known as…

A

HHV-5

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14
Q

CMV routes of transmission

A

1) congenital transfusion
2) sex
3) saliva
4) urine
5) transplant

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15
Q

CMV causes

A

1) mononucleosis with negative mono spot in immunocompetent patients
2) pneumonia in transplant patients
3) AIDS retinitis

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16
Q

where does CMV establish latency?

A

mononuclear cells

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17
Q

CMV retinitis presentation?

A

hemorrhage + cotton-wool exudates + vision loss

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18
Q

other name for roseola infantum

A

exanthema subitum

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19
Q

More common cause of roseola?

A

HHV-7

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20
Q

HHV-8 transmission?

A

sexual contact

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21
Q

where else can HHV-8 affect?

A

GI and lungs

22
Q

what is capos sarcoma?

A

neoplasm of endothelial cells.

23
Q

HSV diagnosis?

A

if on skin/genitalia –> viral culture

herpes encephalitis –> CSF PCR

24
Q

Tzanck test used for..

A

HSV 1 and 2 and VZV

25
Q

characteristic path finding with HSV

A

intranuclear inclusions

26
Q

what receptor does CMV use?

A

integrins (heparan sulfate)

27
Q

what receptor does rabies use?

A

nicotinic AChR

28
Q

what receptor does rhinovirus use?

A

ICAM-1

29
Q

What are the reoviruses?

A

1) coltivirus

2) rotavirus

30
Q

Reovirus strcutre

A

NON enveloped
DS linear, 10-12 segments
Icosahedral capsid (double)

31
Q

coltivirus causes..

A

colorado tick fever

32
Q

1 cause of fatal diarrhea in kids?

A

rotavirus

33
Q

picornavirues

A 
PERCH
Polio
Echovirus
Rhinovirus
Coxsackievirus
HAV
34
Q

picornavirus structrue

A

NON enveloped
SS linear
Icosahedral capsid

35
Q

Echovirus causes…

A

aseptic mengingitis

36
Q

Coxsackievirus causes

A

1) aseptic meningitis
2) herpangina (mouth blisters, fever)
3) hand, foot, and mouth disease
4) myocarditis
5) pericarditis

37
Q

HAV causes..

A

acute viral hepatitis

38
Q

Hepevirus structure

A

non enveloped, SS, positive, icosahedral

39
Q

caliciviruses

A

norovirus

40
Q

flavivirus structure

A

*enveloped

SS, positive, linear, icosahedral capsid

41
Q

faviviruses

A 
HCV
Yellow fever
Dengue
*St. Lous encephalitis
West Nile virus
42
Q

toga viruses…

A

Rubella
Eastern equine encephalitis
Western equine encephalitis

43
Q

toga structure

A

*enveloped

SS, positive, linear, icosahedral capsid

44
Q

retrovirus structure

A

*enveloped

SS, positive, linear, icosahedral capsid (HTLV), HIV = complex and conical capsid.

45
Q

coronaviruses…

A

common cold
SARS
MERS

46
Q

coronavirus structure

A

*enveloped

SS, positive, linear, *helical capsid

47
Q

orthomyxovirus structure

A

*enveloped

SS, negative sense, linear, helical capsid, 8 segments

48
Q

paramyxoviruses…

A

Parainfluenza (croup)
RSV
Measles
Mumps

49
Q

Paramyxovirus structure

A

enveloped, SS, negative sense, linear, *helical capsid

50
Q

aseptic meningitis

A

inflammation of the meninges with no bacterial source.

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