ID 11 Flashcards
HSV-1 route of transmission
respiratory secretions, saliva
HSV-1 causes…
1) gingivostomatitis
2) keratoconjunctivitis
3) herpes labials
4) herpetic whitlow
5) encephalitis
most common cause of sporadic encephalitis?
HSV-1
HSV-1 encephalitis presentation?
altered mental status + seizures + and/or aphasia
neonatal herpes caused by?
HSV-2
more common HSV causing viral meningitis?
HSV-2
VZV also known as
HHV-3
VZV can also cause
1) encephalitis
2) pneumonia
where does VZV establish latency?
dorsal root or trigeminal ganglia
EBV also known as..
HHV-4, herpes virus
EBV transmitted through
respiratory secretions, saliva
most common lymphadenopathy location for mono
posterior cervical nodes
CMV also known as…
HHV-5
CMV routes of transmission
1) congenital transfusion
2) sex
3) saliva
4) urine
5) transplant
CMV causes
1) mononucleosis with negative mono spot in immunocompetent patients
2) pneumonia in transplant patients
3) AIDS retinitis
where does CMV establish latency?
mononuclear cells
CMV retinitis presentation?
hemorrhage + cotton-wool exudates + vision loss
other name for roseola infantum
exanthema subitum
More common cause of roseola?
HHV-7
HHV-8 transmission?
sexual contact
where else can HHV-8 affect?
GI and lungs
what is capos sarcoma?
neoplasm of endothelial cells.
HSV diagnosis?
if on skin/genitalia –> viral culture
herpes encephalitis –> CSF PCR
Tzanck test used for..
HSV 1 and 2 and VZV
characteristic path finding with HSV
intranuclear inclusions
what receptor does CMV use?
integrins (heparan sulfate)
what receptor does rabies use?
nicotinic AChR
what receptor does rhinovirus use?
ICAM-1
What are the reoviruses?
1) coltivirus
2) rotavirus
Reovirus strcutre
NON enveloped
DS linear, 10-12 segments
Icosahedral capsid (double)
coltivirus causes..
colorado tick fever
1 cause of fatal diarrhea in kids?
rotavirus
picornavirues
PERCH Polio Echovirus Rhinovirus Coxsackievirus HAV
picornavirus structrue
NON enveloped
SS linear
Icosahedral capsid
Echovirus causes…
aseptic mengingitis
Coxsackievirus causes
1) aseptic meningitis
2) herpangina (mouth blisters, fever)
3) hand, foot, and mouth disease
4) myocarditis
5) pericarditis
HAV causes..
acute viral hepatitis
Hepevirus structure
non enveloped, SS, positive, icosahedral
caliciviruses
norovirus
flavivirus structure
*enveloped
SS, positive, linear, icosahedral capsid
faviviruses
HCV Yellow fever Dengue *St. Lous encephalitis West Nile virus
toga viruses…
Rubella
Eastern equine encephalitis
Western equine encephalitis
toga structure
*enveloped
SS, positive, linear, icosahedral capsid
retrovirus structure
*enveloped
SS, positive, linear, icosahedral capsid (HTLV), HIV = complex and conical capsid.
coronaviruses…
common cold
SARS
MERS
coronavirus structure
*enveloped
SS, positive, linear, *helical capsid
orthomyxovirus structure
*enveloped
SS, negative sense, linear, helical capsid, 8 segments
paramyxoviruses…
Parainfluenza (croup)
RSV
Measles
Mumps
Paramyxovirus structure
enveloped, SS, negative sense, linear, *helical capsid
aseptic meningitis
inflammation of the meninges with no bacterial source.
