ID 11 Flashcards

1
Q

HSV-1 route of transmission

A

respiratory secretions, saliva

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2
Q

HSV-1 causes…

A

1) gingivostomatitis
2) keratoconjunctivitis
3) herpes labials
4) herpetic whitlow
5) encephalitis

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3
Q

most common cause of sporadic encephalitis?

A

HSV-1

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4
Q

HSV-1 encephalitis presentation?

A

altered mental status + seizures + and/or aphasia

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5
Q

neonatal herpes caused by?

A

HSV-2

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6
Q

more common HSV causing viral meningitis?

A

HSV-2

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7
Q

VZV also known as

A

HHV-3

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8
Q

VZV can also cause

A

1) encephalitis

2) pneumonia

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9
Q

where does VZV establish latency?

A

dorsal root or trigeminal ganglia

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10
Q

EBV also known as..

A

HHV-4, herpes virus

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11
Q

EBV transmitted through

A

respiratory secretions, saliva

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12
Q

most common lymphadenopathy location for mono

A

posterior cervical nodes

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13
Q

CMV also known as…

A

HHV-5

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14
Q

CMV routes of transmission

A

1) congenital transfusion
2) sex
3) saliva
4) urine
5) transplant

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15
Q

CMV causes

A

1) mononucleosis with negative mono spot in immunocompetent patients
2) pneumonia in transplant patients
3) AIDS retinitis

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16
Q

where does CMV establish latency?

A

mononuclear cells

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17
Q

CMV retinitis presentation?

A

hemorrhage + cotton-wool exudates + vision loss

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18
Q

other name for roseola infantum

A

exanthema subitum

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19
Q

More common cause of roseola?

A

HHV-7

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20
Q

HHV-8 transmission?

A

sexual contact

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21
Q

where else can HHV-8 affect?

A

GI and lungs

22
Q

what is capos sarcoma?

A

neoplasm of endothelial cells.

23
Q

HSV diagnosis?

A

if on skin/genitalia –> viral culture

herpes encephalitis –> CSF PCR

24
Q

Tzanck test used for..

A

HSV 1 and 2 and VZV

25
characteristic path finding with HSV
intranuclear inclusions
26
what receptor does CMV use?
integrins (heparan sulfate)
27
what receptor does rabies use?
nicotinic AChR
28
what receptor does rhinovirus use?
ICAM-1
29
What are the reoviruses?
1) coltivirus | 2) rotavirus
30
Reovirus strcutre
NON enveloped DS linear, 10-12 segments Icosahedral capsid (double)
31
coltivirus causes..
colorado tick fever
32
#1 cause of fatal diarrhea in kids?
rotavirus
33
picornavirues
``` PERCH Polio Echovirus Rhinovirus Coxsackievirus HAV ```
34
picornavirus structrue
NON enveloped SS linear Icosahedral capsid
35
Echovirus causes...
aseptic mengingitis
36
Coxsackievirus causes
1) aseptic meningitis 2) herpangina (mouth blisters, fever) 3) hand, foot, and mouth disease 4) myocarditis 5) pericarditis
37
HAV causes..
acute viral hepatitis
38
Hepevirus structure
non enveloped, SS, positive, icosahedral
39
caliciviruses
norovirus
40
flavivirus structure
*enveloped | SS, positive, linear, icosahedral capsid
41
faviviruses
``` HCV Yellow fever Dengue *St. Lous encephalitis West Nile virus ```
42
toga viruses...
Rubella Eastern equine encephalitis Western equine encephalitis
43
toga structure
*enveloped | SS, positive, linear, icosahedral capsid
44
retrovirus structure
*enveloped | SS, positive, linear, icosahedral capsid (HTLV), HIV = complex and conical capsid.
45
coronaviruses...
common cold SARS MERS
46
coronavirus structure
*enveloped | SS, positive, linear, *helical capsid
47
orthomyxovirus structure
*enveloped | SS, negative sense, linear, helical capsid, 8 segments
48
paramyxoviruses...
Parainfluenza (croup) RSV Measles Mumps
49
Paramyxovirus structure
enveloped, SS, negative sense, linear, *helical capsid
50
aseptic meningitis
inflammation of the meninges with no bacterial source.