ID 7 Flashcards

1
Q

classic source of yersinia

A

pet feces from puppies + contaminated milk + pork

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2
Q

cause of pseudo appendicitis with yersinia?

A

mesenteric adenitis or inflammation of terminal ileum.

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3
Q

h pylori triple positive?

A

catalase, oxidase, and urease positive

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4
Q

treatment for h pylori?

A

amoxicillin + clarithromycin + PPI

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5
Q

what do you give someone for h pylori if they have a penicillin allergy?

A

metronidazole

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6
Q

biggest spirochete?

A

borrelia (borrelia is big). Thus, only one that can stained and seen with light microscopy.

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7
Q

leptospirosis presentation

A

flu-like symptoms + calf myalgia + jaundice + photophobia with conjunctival suffusion (erythema without exudate)

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8
Q

other name for Weil disease

A

icterohemorrhagic leptospirosis

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9
Q

Weil disease presentatoin

A

severe form of leptospirosis with jaundice and azotemia from liver and kidney dysfunction + fever + hemorrhage + anemia.

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10
Q

what type of organism is babesia?

A

protozoan

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11
Q

stage 2 lyme disease

A

Early disseminated: secondary lesions + carditis + AV block + bell palsy + migratory myalgias/transient arthritis

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12
Q

stage 3 lyme disease

A

late disseminated: encephalopathies + chronic arthritis

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13
Q

latent syphilis

A

positive serology without symptoms

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14
Q

secondary syphilis characteristics

A

1) disseminated disease

2) *patchy hair loss

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15
Q

Difference between VDRL/RPR and FTA-ABS?

A

VDRL/RPR is nonspecific and needs to be confirmed with FTA-ABS, which is specific.

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16
Q

signs of tabes dorsalis

A

1) broad-based ataxia
2) positive romberg
3) charcot joint
4) stroke without hypertension

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17
Q

neurosyphilis

A

tabes dorsalis or general paresis

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18
Q

general paresis

A

Severe neuropsychiatric disorder caused by chronic syphilis meningoencephalitis that leads to cerebral atrophy.

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19
Q

neurosyphilis diagnosis

A

Test spinal fluid with VDRL + FTA-ABS + PCR.

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20
Q

What are rhagades?

A

linear scars at angle of mouth, characteristic of congenital syphilis.

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21
Q

How do you prevent congenital syphilis?

A

Treat mother early in pregnancy (placental transmission typically occurs after first trimester)

22
Q

snuffles?

A

nasal discharge

23
Q

congenital syphilis presentation

A

1) rhagades
2) snuffles
3) saddle nose
4) notched/Hutchinson teeth
5) mulberry molars
6) short maxilla
7) saber shins
8) CN VIII deafness

24
Q

What does VDRL detect?

A

antibody reacting to beef cardiolipin

25
Q

VDRL characteristics

A

sensitive but not specific

26
Q

false positives on VDRL?

A

In back corner Anna’s dad holding wheelchair + josh in a net on left + Claire with a rifle on right + sugar cane + lepromatous guy on rachel’s lap + Rachel Ancar in a wheelchair + prostitute covered in sugar cane laying on shelf above/false positives on VDRL can be due to viral infection (mono, hepatitis) + drugs (chlorpromazine; procainamide) + rheumatic fever + lupus + leprosy + anticardiolipin antibodies (APA syndrome).

27
Q

Jarisch-herxheimer presentation

A

fever + chills + headache + myalgia

28
Q

borrelia recurrentis disease?

A

relapsing fever (borrelia RECURRENTis)

29
Q

borrelia recurrentis source?

A

Lice

30
Q

Why do lice cause recurring fever?

A

variable surface antigens

31
Q

other name for brucellosis?

A

undulant fever

32
Q

brucella source?

A

unpasteurized dairy

33
Q

coxiella burnetii source?

A

aerosols of cattle/sheep amniotic fluid

34
Q

ehrlichia source

A

amblyomma (lone star tick)

35
Q

pasteurella multocida causes…

A

1) cellulitis

2) *osteomyelitis

36
Q

pasteurella multocida sources

A

cat or dog bite or other animal bite

37
Q

rickettsia prowazekii transmission and source

A

human to human via human body lice

38
Q

rickettsia rickettsia causes

A

rocky mountain spotted fever

39
Q

rickettsia rickettsia source

A

dermacentor (dog tick)

40
Q

rickettsia typhi source

A

fleas

41
Q

Don’t confuse yersinia pestis with yersinia enterocolitica

A

ok

42
Q

yersinia pestis source

A

fleas

43
Q

gardnerella sex caveat

A

associated with sexual activity but not sexually transmitted

44
Q

clue cell description

A

cell with “stippled” appearance along outer margin

45
Q

gardnerella diagnosis

A

amine whiff test–mixing discharge with 10% of KOH enhances fishy odor.

46
Q

r typhi presentation

A

rash starts centrally and spreads out

47
Q

rocky mountain spotted fever triad

A

headache + fever + rash (vasculitis)

48
Q

characteristic path finding with ehrlichiosis

A

monocytes with morulae (mulberry like inclusions)

49
Q

characteristic path finding with anaplasmosis

A

granulocytes with morulae

50
Q

Q fever presentation

A

pneumonia

51
Q

Why is Q fever queer?

A

No rash or vector and coxiella can survive outside in endospore form. Not in rickettsia genus.