Biochem pathways

Question 1

Draw out homocystinuria biochem

Answer 1

FA 96

Question 2

Biochem types of homocystinuria and how treatment affects that

Answer 2

1) Cystathionine synthase deficiency (treatment: decreased methionine, increase cysteine, increase B12 and folate in diet)
2) Decreased affinity of cystathionine synthase for pyridoxal phosphate (treatment = increase B6 and cysteine in diet)
3) methionine synthase (aka homocysteine methyltransferase) deficiency.