G10 DNA(Slides Summary) Flashcards

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1
Q

monomers of nucleic acids

A

nucleotides

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2
Q

components of nucleotides

A

a five-carbon sugar
a phosphate group
a nitrogenous base

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3
Q

strand of nucleic acids is formed by linked nucleotides together by

A

phosphodiester bonds

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4
Q

DNA strand has a _ _ where the phosphate group is found

A

5’ end

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5
Q

DNA strand has a _ _ where the sugar molecule is located

A

3’ end

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6
Q

Double helix is _ - handed

A

right

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7
Q

The double helix twissts in the clockwise direction which results in the formation of major and minor _.

A

grooves

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8
Q

The DNA sequence can be represented by its nitrogenous bases.

A
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9
Q

are nucleic acids involved in protein synthesis

A

Ribonucleic acid (RNA)

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10
Q

Ribonucleic acid (RNA) are nucleic acids involved in protein synthesis. It uses _ instead of thymine as one of its nitrogenous bases.

A

uracil

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11
Q

a principle that the genetic information contained in the DNA is replicated and transferred to RNA molecules that direct the synthesis of protein molecules

A

central dogma of molecular biology

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12
Q

a semiconservative process wherein DNA molecules are duplicated during cell division and passed on to each daughter cell.

A

Replication

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13
Q

involves unwinding and unzipping by the helicase and the stabilization by the topoisomerase and SSBPs

A

Initiation of replication

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14
Q

involves the continous and discontinous synthesis in the leading and lagging strands by the DNA polymerase III

A

Elongation stage (of replication)

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15
Q

occurs when the two strands are already bound to each other. DNA polymerase I replaces primers, and DNA ligase seals the gaps.

A

Termination of replication

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16
Q

The cell has no 100%-accurate replication machinery. However, it has proofreading and mismatch repair mechanisms.

A
17
Q

are involved in the translation and transcription of genetic information in DNA

A

Ribonucleic acids or RNAs

18
Q

Ribonucleic acids contains uracil instead of _.

A

thymine

19
Q

process of converting the genetic information in DNA to synthesize mRNA

A

Transcription

20
Q

three types of RNA

A
messenger RNA (mRNA)
transfer RNA (tRNA)
ribosomal RNA (rRNA)
21
Q

is the enzyme responsible for synthesizing the complementary RNA called primary transcript

A

RNA polymerase

22
Q

RNA polymerase is the enzyme responsible for synthesizing the complementary RNA called

A

primary transcript

23
Q

Transcription starts at

A

promoter region

24
Q

Transcription ends in

A

terminator sequence

25
Q

Transcription starts at the promoter region and ends in the terminator sequence. The mRNA detaches to form a

A

hairpin structure

26
Q

_ _ of the pre-mRNA involves splicing to remove introns and the addition of 5’ cap and 3’ poly-A tail

A

Post-transcriptional modification

27
Q

Post-transcriptional modification of the pre-mRNA involves splicing to remove _ and the addition of 5’ cap and 3’ poly-A tail.

A

introns

28
Q

Post-transcriptional modification of the pre-mRNA involves splicing to remove introns and the addition of 5’ _ and 3’ poly-A _.

A

cap, tail

29
Q

involves the formation of the translation complex consisting of the mRNA, 70S ribosome, and the initiator tRNA

A

Initiation of translation

30
Q

involves the cycle of entry into A site and exit through E site by the tRNAs

A

Elongation of translation

31
Q

Elongation involves the cycle of entry into A site and exit through E site by the tRNAs. The _ _ elongates in this stage.

A

polypeptide chain

32
Q

involves the recognition of one of the three stop codons (i.e., UAA, UAG, or UGA).

A

Termination of translation

33
Q

three stop codons

A

UAA
UAG
UGA