Digestion & Metabolism 2: Feline Biliary Sx Flashcards
3 BILIARY surgical syndromes?
- EXTRA-HEPATIC BILIARY TRACT OBSTRUCTION
- GALLBLADDER MUCOCELE
- BILE PERITONITIS
EXTRA-HEPATIC BILIARY TRACT OBSTRUCTION…
3 forms?
1. = 2 common examples?
2. = 4 common examples?
3. = 1 common example?
- EXTRALUMINAL = OUTSIDE biliary system, usually from PANCREAS
–> PANCREATITIS
–> PANCREATIC NEOPLASIA - INTRALUMINAL
–> CHOLELITHIASIS = stones in GALLBLADDER
–> GALLBLADDER MUCOCELE = from bile CONGEALING
–> FB
–> NEOPLASIA - INTRAMURAL
–> NEOPLASIA usually of GALLBLADDER or BILE DUCT
why can the bile duct get so easily OBSTRUCTED?
has SMALL LUMEN
what PART of bile makes bile flow obstruction so bad?
what CAN happen if BILE OBSTRUCTED? (2)
the BILE SALTS make obstruction bad
what CAN happen?
1. BACTERIAL OVERGROWTH from SALT, usually GRAM NEGATIVE that can MAKE ENDOTOXINS that get absorbed
2. LIVER has DECREASED CLEARANCE due to obstructed bile ducts
SECONDARY diseases that occur due to BILE DUCT OBSTRUCTIONS (6)
these are ALL due to ____ as a result of bile obstruction
SECONDARY diseases…
1. DECREASED MYOCARDIAL CONTRACTILITY
2. HYPOTENSION
3. ACUTE RENAL FAILURE
4. COAGULOPATHIES (DIC)
5. GI HEMORRHAGE
6. DELAYED WOUND HEALING
ALL due to ENDOTOXEMIA
5 _____-_____clinical signs of BILE DUCT OBSTRUCTION?
what is this SECONDARY to?
if ____ is ABOVE ____-____ mg/dL, then EASIER TO DIAGNOSE
5 NON-SPECIFIC signs?
1. LETHARGY
2. ANOREXIA
3. VOMITING
4. DIARRHEA
5. ICTERUS
+/- ABDOMINAL PAIN
secondary all to ENDOTOXEMIA
BILIRUBIN above 1.5-2 mg/dL –> GOOD FOR BILE DUCT OBSTRUCTION
CLIN PATH findings for BILE DUCT OBSTRUCTION (6)
- HYPERBILIRUBINEMIA
- INCREASED ALP
- INCREASED ALT/GGT (liver enzymes)
- LEUKOCYTOSIS
- HYPOALBUMINEMIA
- PROLONGED COAGULATION
what is the BEST imaging technique for BILE DUCT OBSTRUCTION?
what 4 things could we possibly see?
what OTHER imaging could we possibly use & what specific reason would it be best for?
ABDOMINAL ULTRASOUND IS BEST
4 things to see on ABDOMINAL US…
1. CHOLELITHS
2. BILIARY or PANCREATIC NEOPLASIA
3. GALLBLADDER MUCOCELES
4. ENLARGED BILE DUCT/GALLBLADDER
can also do RADS, but really only best for CHOLELITHS (stones)
SCINTIGRAPHY…
= what is it showing in BILE DUCT OBSTRUCTION?
how can we ID dz & what IS the dz?
= shows HOW FAST CONTRAST passes through GALLBLADDER –> INTESTINES
ID BILIARY TRACT OBSTRUCTION because NEEDS TO GET TO INTESTINES WITHIN A CERTAIN AMOUNT OF TIME
BILIARY MUCOCELE…
commonality?
underlying disease is called….
what do we see grossly?
the GALLBLADDER can look… (2)
this is often an ____ finding
COMMON
underlying disease = CYSTIC MUCINOUS HYPERPLASIA of the GALLBLADDER
grossly? = BILE becomes THICK, SHINY & CONGEALED and CANNOT GO THROUGH BILIARY TRACT
GALLBLADDER can look…
1. GREEN
2. THIN-WALLED
often INCIDENTAL FINDING
ID DZ (overall dz & underlying)
BILIARY MUCOCELE
from CYSTIC MUCINOUS HYPERPLASIA
in SEVERE cases of BILIARY MUCOCELE…
now becomes…
PRESSURE NECROSIS of GALLBLADDER WALL can lead to RUPTURE & BILE PERITONITIS
becomes AN EMERGENCY
BILIARY MUCOCELE gets DEFINITIVE diagnosis via….
gallbladder has a ____ ____ appearance or resembles a ____
via ULTRASOUND (more useful & sensitive diagnostic tests)
gallbladder has CLASSICAL STELLATE APPEARANCE or resembles a “KIWI”
BILE PERITONITIS…
is often a RESULT of…
3 causes? which is the most common?
is often a RESULT of EXTRA-HEPATIC BILIARY TRACT OBSTRUCTION causing BILE LEAKAGE into abdomen
3 causes?
1. TRAUMA like a PENETRATING WOUND
2. COMPLICATION after a SURGERY for BILIARY TRACT OBSTRUCTION
3. RUPTURED GALLBLADDER MUCOCELE from PRESSURE NECROSIS
BILE PERITONITIS…
what CBC finding do we have?
2 BEST diagnostics?
WHAT parameter is considered DIAGNOSTIC for BILE PERITONITIS?
this disease is ALWAYS considered a….
on CBC = HYPERBILIRUBINEMIA
2 BEST diagnostics?
1. ABDOMINAL US
2. ABDOMINOCENTESIS & ANALYSIS
DIAGNOSTIC = If BILIRUBIN IN EFFUSION is ≥ 2X BILIRUBIN in SERUM
ALWAYS considered a SURGICAL EMERGENCY!