Defense & Barriers 2: Skin Patterns Flashcards
describe the region of the lesion & what it is
ALOPECIA in DORSO-CAUDAL LUMBAR AREA
from FLEA BITE HYPERSENSITIVITY in CATS, common presentation
name the disease
feline atopic skin syndrome
what disease is this?
acute clinical signs? (3)
chronic clinical signs? (2)
FLEA BITE HYPERSENSITIVITY
ACUTE signs?
1. papules
2. crusted papules
3. hot spots
CHRONIC signs?
1. lichenification
2. hyperpigmentation
what disease is this?
lesions? (3)
MALASSEZIA DERMATITIS
lesions?
1. erythema
2. yellow/brownish greasy scales
3. hyperpigmentation
what disease is this?
where are lesions usually found?
CANINE ATOPIC DERMATITIS
lesions usually found in FLEXURAL FOLDS (belly, armpit, inguinal region) and EARS
what disease is this?
PATTERN ALOPECIA, NON-PATHOGENIC
what kind of lesions is this?
what 2 things usually found inside?
PUSTULE
EOSINOPHILS & NEUTROPHILS
skin has ____ means to react to injury
LIMITED
use ___ magnification to form dermatological differential diagnoses, and use ___ to divide and narrow these diagnoses
LOW, HIGH
carcinoma vs. sarcoma terms for neoplastic histologic patterns?
carcinoma = nests, cords, glands
sarcoma = streams, whorls, bundles
name of disease?
how rare?
what kind of pattern is this?
culicuoides hypersensitivity, “itchy skin rash”
MOST COMMON SKIN IRRITATION IN HORSES
PERIVASCULAR DERMATITIS
name of disease?
what kind of pattern is this?
CANINE ATOPIC DERMATITIS
PERIVASCULAR DERMATITIS
name of disease?
what kind of pattern is this?
FLEA BITE HYPERSENSITIVITY
PERIVASCULAR DERMATITIS
what kind of pattern is this?
duration?
PERIVASCULAR DERMATITIS
CHRONIC SURFACE TRAUMA
secondary effects of perivascular dermatitis? (3)
- TRAUMA to the surface of the skin
- proliferation of BACTERIA, particularly Staph pseudintermedius and scheiferi
- MALASSEZIA infection
perivascular dermatitis
= what is it & how cells act
2 things typical for it?
diagnostic strength?
= ANY kind of allergic skin disease pattern, non-specific; INFLAMMATORY CELLS come OUT of vessel and STAY AROUND IT
2 things typically in perivascular dermatitis reactions?
–> LATE-PHASE TYPE 1 HYPERSENSITIVITY REACTION
–> often see ACANTHOSIS
WEAK diagnostic strength because VERY COMMON
PARAKERATOTIC hyperkeratosis
found in what kind of pattern?
3 diseases it can indicate?
found in PERIVASCULAR DERMATITIS
indicates…
1. zinc-responsive dermatitis
2. metabolic disturbance
3. superficial necrolytic dermatitis
what disease is this?
what type of pattern?
disease = NOTOEDRIC MANGE
PERIVASCULAR DERMATITIS
what disease is this?
pathogenesis?
what type of pattern? **something specific present
SUPERFICIAL NECROLYTIC DERMATITIS
pathogenesis?
–> occurs due to HEPATOPATHY where there’s LOW CIRCULATING AMINO ACIDS and thus NOT ENOUGH NUTRITION FOR SKIN TO UNDERGO APOPTOSIS
it’s a PERIVASCULAR DERMATITIS pattern, particularly PARAKERATOTIC hyperkeratosis
interface dermatitis pattern
= what is it?
diagnostic strength?
2 diseases that usually manifest?
= immune-mediated pattern where inflammatory cells target basal membrane zone & keratinocytes
STRONG diagnostic strength!
usually CUTANEOUS LUPUS and CYTOTOXIC DERMATITIS
disease name?
pattern?
disease = CANINE NASAL LOCALIZED DISCOID LUPUS
INTERFACE pattern
disease name?
pattern?
disease = EXFOLIATIVE CANINE LUPUS
INTERFACE pattern
intraepidermal pustular dermatitis pattern
characterized by what? (easy answer)
causes… (2)
diagnostic strength?
characterized by PUSTULES IN EPIDERMIS
causes?
1. pemphigus foliaceus
2. pustular foliaceus
diagnostic strength?
STRONG
disease name?
pattern?
pathognomonic clinical sign?
PEMPHIGUS FOLIACEUS
INTRAEPIDERMAL PUSTULAR DERMATITIS PATTERN
pathognomonic clinical sign = CRUST on ear
disease name?
pattern?
pathophysiology?
PEMPHIGUS FOLIACEUS
INTRAEPIDERMAL PUSTULAR DERMATITIS PATTERN
pathophysiology?
often occurs as TYPE 2 HYPERSENSITIVITY REACTION where Abs are made against DESMOCOLLIN-1 in DESMOSOMES
nodular dermatitis pattern
alternative term?
= what do we see? (2, one is very important)
what 2 types of infections usually occur with this?
what determines how we make a diagnosis?
also called DIFFUSE dermatitis
= aggregates cells in epidermis & FURUNCULOSIS
usually from BACTERIAL or MYCOBACTERIAL infection
diagnosis depends on TYPE OF INFLAMMATORY INFILTRATE
panniculitis pattern
= definition
what disease in cats vs. dogs?
= inflammation of pannicular adipose tissue
DOGS = STERILE IDIOPATHIC CONDITION
CATS = MYCOBACTERIOSIS
what disease is this?
what pattern?
PEMPHIGUS FOLIACEUS
INTRAEPIDERMAL PUSTULAR DERMATITIS
what pattern is this?
SUPEPIDERMAL VESICULAR DERMATITIS
subepidermal vesicular dermatitis pattern
affects WHAT?
diagnostic strength?
2 types of diseases it causes? (+ specific pathologies)
affects BASEMENT MEMBRANE ZONE
STRONG diagnostic strength
2 types of diseases it causes?
1. CONGENITAL GENODERMATOSES = DEFECT IN THE BASEMENT MEMBRANE ZONE
–> causes EPIDERMOLYSIS BULLOSA
- ACQUIRED AUTOIMMUNE DISEASE affecting component of BMZ
–> causes MUCOUS MEMBRANE PEMPHIGOID & EBA
what disease is this?
what pattern?
MUCOUS MEMBRANE PEMPHIGOID
SUBEPIDERMAL VESICULAR DERMATITIS PATTERN
what disease is this? (hint = INFLAMMATION)
FOLLICULITIS
what PATTERN is this?
INTERFACE dermatitis
what PATTERN is this?
ACUTE PERIVASCULAR dermatitis
