6.5: Regulation of enzyme activity helps control metabolism

Question 1

Allosteric regulation

Answer 1

where a protein’s function at one site is affected by the binding of regulatory molecules at a separate site, stimulation or inhibition, protein bind to an allosteric site on the enzyme, causes shape change, and can regulate enzyme

Question 2

allosteric site

Answer 2

where the activator or inhibitor binds, is where 2 subunits join

Question 3

How often do enzymes change shape?

Answer 3

the form of these enzymes always change shape, the binding of these coenzymes make the shape stabilized

Question 4

What are the components of an enzyme that needs allosteric regulation?

Answer 4

most enzymes that are allosterically regulated are made of 2 or more subunits with polypeptide chains with their own active site

Question 5

cooperativity

Answer 5

a mechanism that amplifies the response of enzymes substrate attached to one active site that activates the others, oxygen does this by one attaching to one binding site of hemoglobin

Question 6

feedback inhibition

Answer 6

a metabolic pathway is halted by the inhibitory binding of its end product to an enzyme that acts early in the pathway, turns off the pathway when there are too many end products

Question 7

How are enzymes organized in a cell?

Answer 7

enzymes concentrated in places where that reaction mainly occurs, the cell structure brings order to metabolic pathways, certain arrangments help the reaction go in a sequential order