12.2: Sex-linked genes exhibit unique patterns of inheritance Flashcards
What is sex determined by?
Sex is determined by chromosomes
How are sperms and ovaries split?
44 sperms(split by X and Y) and 22 ovaries
SRY
sex-determining region of Y(gonads develops testes), if it is absent, ovaries for even in an XY
sex-linked genes
A Gene located on either chromosome
X/Y linked genes
Genes for that specific chromosomes, very few are on the Y
WNT4
develops ovary, if the surplus amount on XY embryos, they grow ovaries instead of testes
hemizygous
only one allele, semi genotype, XY
Duchenne muscular dystrophy, males
the lack of a key muscular protein called dystrophin, causes the chronic weakening of muscles, very specific to a locus on the X chromosome
Hemophilia, males
X linked and is an absence of proteins needed for blood clotting, cuts can lead to bleeding out
What happens during early embryonic development in females?
During early embryonic development for females, almost all the X chromosomes are inactivated
Barr body
a condensed form of an inactivated X chromosome, are reactivated in the ovaries and in the ovaries only, resulting in gametes with X chromosomes
Mosaicism
Cells independently inactivate chromosomes, half will express one allele while the others express another allele