12.2: Sex-linked genes exhibit unique patterns of inheritance Flashcards

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1
Q

What is sex determined by?

A

Sex is determined by chromosomes

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2
Q

How are sperms and ovaries split?

A

44 sperms(split by X and Y) and 22 ovaries

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3
Q

SRY

A

sex-determining region of Y(gonads develops testes), if it is absent, ovaries for even in an XY

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4
Q

sex-linked genes

A

A Gene located on either chromosome

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5
Q

X/Y linked genes

A

Genes for that specific chromosomes, very few are on the Y

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6
Q

WNT4

A

develops ovary, if the surplus amount on XY embryos, they grow ovaries instead of testes

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7
Q

hemizygous

A

only one allele, semi genotype, XY

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8
Q

Duchenne muscular dystrophy, males

A

the lack of a key muscular protein called dystrophin, causes the chronic weakening of muscles, very specific to a locus on the X chromosome

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9
Q

Hemophilia, males

A

X linked and is an absence of proteins needed for blood clotting, cuts can lead to bleeding out

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10
Q

What happens during early embryonic development in females?

A

During early embryonic development for females, almost all the X chromosomes are inactivated

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11
Q

Barr body

A

a condensed form of an inactivated X chromosome, are reactivated in the ovaries and in the ovaries only, resulting in gametes with X chromosomes

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12
Q

Mosaicism

A

Cells independently inactivate chromosomes, half will express one allele while the others express another allele

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