6.3: ATP powers cellular work by coupling exergonic reactions to endergonic reactions Flashcards
3 types of jobs of a cell
Chemical work: the pushing of endergonic reactions, synthesis of polymers from monomers
Transport work: the pumping of substances across membranes against the direction of spontaneous movement
Mechanical work: contractions of muscles and movement of chromosomes during cellular reproduction
energy coupling
use of an exergonic process to drive an endergonic process
what mediates energy coupling
ATP
ATP(adenosine triphosphate), what are the components
contains sugar ribose, with a nitrogen base(adenine), and a chain of 3 phosphates
ΔG for the hydrolysis of ATP
-7.3kcal/mol,
Why does ATP release energy
The repulsion from the 3 negatively charged phosphates creates high instability when one phosphate leaves, energy is released
What harness the energy released during ATP hydrolysis in several ways to perform the three types of cellular work ?
Cell’s proteins
What type of reactions do ATP hydrolysis power
endergonic reactions use ATP hydrolysis
phosphorylated intermediate, give examples
the recipient of the inorganic phosphate group(covalently bonded)
work movement of motor proteins and shape changes are due to phosphorylation
How is ATP regenerated
the coupling of energy-yielding and energy-consuming processes , ADP + P makes ATP + H2O which is endergonic, vice versa for the reverse