[36] 3D Bioprinting and Biofabrication Flashcards

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1
Q

What is 3D Bioprinting?

A

A technique used to create complex 3D structures using biological materials, typically cells and biomaterials, often used in tissue engineering.

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2
Q

What is Biofabrication?

A

A broad term that refers to the production of artificial tissues and organs to address health challenges in medicine.

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3
Q

How is 3D Bioprinting related to Biofabrication?

A

3D Bioprinting is a method used in the process of Biofabrication.

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4
Q

What are the main applications of 3D Bioprinting and Biofabrication?

A
  • Tissue engineering and regenerative medicine
  • Drug testing and clinical trials
  • Personalized medicine
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5
Q

What is Tissue Engineering in the context of 3D Bioprinting and Biofabrication?

A

The practice of combining scaffolds, cells, and biologically active molecules into functional tissues.

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6
Q

How does 3D Bioprinting contribute to Regenerative Medicine?

A

It enables the creation of complex tissues and organs that can be used for transplantation and repair of damaged tissues.

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7
Q

How does 3D Bioprinting aid in Drug Testing and Clinical Trials?

A

By providing realistic, high-fidelity 3D models of human organs and tissues for drug testing and development.

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8
Q

How does 3D Bioprinting support Personalized Medicine?

A

By allowing the creation of patient-specific tissues and organs, leading to more effective treatments.

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9
Q

What types of bioinks are used in 3D Bioprinting?

A
  • Cell-laden bioinks
  • Acellular bioinks
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10
Q

What is a Cell-laden Bioink?

A

A type of bioink that contains living cells.

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11
Q

What is an Acellular Bioink?

A

A type of bioink that does not contain living cells, but often includes other biological materials like proteins and growth factors.

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12
Q

What is the role of a Scaffold in 3D Bioprinting?

A

Provides a temporary structure for cell attachment and growth, allowing the formation of tissues.

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13
Q

How does 3D Bioprinting contribute to the field of Biomedical Engineering?

A

By providing a novel way to create complex, customized biological structures for research and clinical applications.

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14
Q

What are the challenges associated with 3D Bioprinting and Biofabrication?

A
  • Biomaterial selection and design
  • Ensuring cell viability during printing
  • Achieving appropriate tissue functionality
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15
Q

What factors are important in choosing a Bioink for 3D Bioprinting?

A
  • Biocompatibility
  • Printability
  • Mechanical stability
  • Cell functionality
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16
Q

What is Biocompatibility in the context of 3D Bioprinting?

A

The ability of a material to perform with an appropriate host response in a specific situation.

17
Q

What is Printability in the context of 3D Bioprinting?

A

The ability of a bioink to maintain a stable structure during and after the printing process.

18
Q

How can cell viability be affected during 3D Bioprinting?

A

The physical and chemical conditions during the printing process can potentially damage the cells.

19
Q

What is meant by tissue functionality in the context of 3D Bioprinting?

A

The tissue’s ability to perform the specific physiological functions of the tissue or organ being replicated.

20
Q

What advancements are expected in the future of 3D Bioprinting and Biofabrication?

A

Greater precision and control in printing, increased range of printable materials, enhanced tissue functionality, and wider clinical applications such as full organ transplants.