[15] Microbial and Viral Genomics Flashcards

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1
Q

What is genomics?

A

The study of an organism’s entire genetic makeup.

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2
Q

What is microbial genomics?

A

The study of the full genetic material of microorganisms.

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3
Q

What is viral genomics?

A

The study of the full genetic material of viruses.

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4
Q

What’s the significance of microbial genomics?

A

It helps us understand the diversity, evolution, and adaptation mechanisms of microorganisms.

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5
Q

What’s the significance of viral genomics?

A

It aids in understanding the origins, evolution, and epidemiology of viruses.

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6
Q

What are the key components of microbial genomes?

A
  • Chromosomes
  • Plasmids
  • Transposons
  • Integrons
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7
Q

What are the key components of viral genomes?

A
  • DNA or RNA (single-stranded or double-stranded)
  • Protein coat (capsid)
  • Envelope (in some viruses)
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8
Q

Initials: DNA

A

Deoxyribonucleic Acid

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9
Q

Initials: RNA

A

Ribonucleic Acid

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10
Q

How does microbial genomics contribute to disease understanding?

A

It helps identify pathogenic microorganisms, understand their resistance mechanisms, and aids in the development of new treatment strategies.

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11
Q

How does viral genomics contribute to disease understanding?

A

It helps in identifying and characterizing viruses, tracking their spread and evolution, and contributes to the development of vaccines and antivirals.

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12
Q

What is a chromosome in microbial genomics?

A

A circular or linear DNA molecule that contains most of the genetic information of the microorganism.

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13
Q

What is a plasmid?

A

A small, circular DNA molecule that is separate from the chromosome and can replicate independently.

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14
Q

What is a transposon?

A

A DNA sequence that can change its position within the genome, potentially causing mutations and altering the genome’s size.

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15
Q

What is an integron?

A

A genetic unit capable of capturing and expressing genes, particularly those conferring antibiotic resistance.

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16
Q

What is a capsid in viral genomics?

A

A protein shell that encloses the viral genome.

17
Q

What is a viral envelope?

A

A lipid bilayer that surrounds some viruses, acquired from the host cell membrane.

18
Q

What are the methods used in microbial and viral genomics?

A
  • Whole genome sequencing
  • Metagenomics
  • Comparative genomics
  • Functional genomics
19
Q

What is whole genome sequencing?

A

A process that determines the complete DNA sequence of an organism’s genome.

20
Q

What is metagenomics?

A

The study of genetic material directly from environmental samples, allowing for the study of communities of organisms.