[17] Bioinformatics and Computational Biology Flashcards
What is bioinformatics?
The use of software and computational methods to analyze and interpret biological data.
What is computational biology?
The development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques to the study of biological systems.
How does bioinformatics contribute to understanding biology?
It helps in the analysis, interpretation, and storage of complex biological data like genetic codes.
How does computational biology contribute to understanding biology?
It aids in the modeling and understanding of biological systems through simulations and mathematical models.
What are some typical tasks in bioinformatics?
- Sequence alignment
- Genome annotation
- Computational evolutionary biology
- Protein structure alignment
What are some typical tasks in computational biology?
- Mathematical modeling
- Computational simulation techniques
- Systems analysis
- Bio-imaging
What is sequence alignment in the context of bioinformatics?
The practice of arranging sequences of DNA, RNA, or protein to identify regions of similarity.
What is genome annotation in the context of bioinformatics?
The process of identifying the locations of genes and all coding regions in a genome, and determining what those genes do.
What is computational evolutionary biology?
It involves the use of computational methods to analyze patterns of evolutionary biology like phylogenetics, evolution of genes, and population genetics.
What is protein structure alignment in the context of bioinformatics?
The comparison of protein structures to deduce functional or evolutionary relationships.
What is mathematical modeling in the context of computational biology?
The process of creating mathematical equations that describe the behavior of biological systems.
What is computational simulation techniques in computational biology?
Methods used to simulate biological systems, which can help to understand and predict the system’s behavior.
What is systems analysis in the context of computational biology?
The use of mathematical models and simulations to analyze and understand complex biological systems.
What is bio-imaging in the context of computational biology?
The capture, processing, and visualization of images of biological systems.
What are the applications of bioinformatics?
- Genome mapping
- Drug discovery
- Personalized medicine
- Evolutionary studies
What are the applications of computational biology?
- Understanding complex biological systems
- Predicting behavior of biological systems
- Drug design
- Medical imaging
What are the limitations of bioinformatics?
- Need for large computational resources
- Data reliability and standardization issues
What are the limitations of computational biology?
- Complexity of biological systems
- Need for accurate models and simulations
How does bioinformatics complement traditional biology?
It allows for analysis of large volumes of data and prediction of gene function, aiding in genomic and post-genomic research.
How does computational biology complement traditional biology?
It offers tools for understanding complex biological systems at a level of detail not achievable with experimental methods alone.
