12.7- Neuron Physiology Flashcards
Voltage
The amount of difference in electrical charge between two areas
Current
The movement of charged particles across the barrier that represents this charge difference. Increased movement of charged particles = greater current.
Resistance
The opposition to the movement of charged particles. This is the barrier between the charged areas.
What is Ohm’s law?
Current= voltage/resistance
What is the resting stated of the synaptic knob?
More Ca+ in the interstitial fluid (IF) than in the cytosol due to the Ca+ pump.
Membrane potential?
The charge difference between the interstitial fluid and the cytosol of the cell.
What is the RMP?
Resting membrane potential- -70mV but can range between -40 and -90 mV.
What other than Na+, K+ and Cl- are needed to maintain RMP?
Negatively charged phosphate and negatively charged protein molecules.
What assists and apposes the movement of K+ outside the neuron?
Chemical concentration gradient helps it, but the electrical concentration gradient resists it.
Which directions do leaky channels direct K+ and Na+?
Na+ comes in and K+ goes out. These together create the RMP of -70 mV.
Which kind of channel is more common? Na+ or K+ leaky channels?
K+ channels. Thus more K+ can leak out than Na+ can leak in.
What is the primary/secondary roll of the Na+/K+ pump?
Primary- creates concentration gradient
Secondary- Contributes -3 mV toward RMP