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Microbio > Virulence factors/treatments for test 2 > Flashcards

Virulence factors/treatments for test 2 Flashcards

1
Q

What are the virulence factors for Pseudomonas?

A
  1. Pyocyanin
  2. Pyoverdin
  3. Phospholipase C
  4. Toxin A
  5. Leukocidin
  6. Capsule
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2
Q

What are the virulence factors for Staph Aureus?

A
  1. Coagulase
  2. Protein A
  3. PVL
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3
Q

What are the virulence factors for Strep pneumo?

A
  1. Surface adhesins
  2. IgA protease
  3. Pneumolysin
  4. Teichoic acid
  5. Capsule
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4
Q

What are the virulence factors for Klebsiella?

A

LPS

capsule

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5
Q

What are the virulence factors for Pertussis?

A

Filamentous hemagglutinin

Pertussis toxin

Adenylate cyclase

LPS

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6
Q

What are the virulence factors for Mycoplasm?

A

P1 adhesin

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7
Q

What are the virulence factors for H. influenzae?

A
  1. LPS
  2. IgA protease
  3. PRP
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8
Q

What is the treatment for Staph aureus (not MRSA)?

A

PCN or cephalosporins

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9
Q

What is the treatment for MRSA?

A

Vanco

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10
Q

What is the treatment for pseudomonas?

A

Picaricillin, Ticarcillin, and an aminoglycoside

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11
Q

What is the treatment for Strep pneumo?

A

PCN or macrolides

If serious, then azithromycin + cephalosporin

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12
Q

What is the treatment for gram negative bacteria?

A

Aminoglycosides and a beta lactam

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13
Q

What is the treatment for Atypical pneumonia besides legionella?

A

Tetracycline and a macrolide

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14
Q

What is the treatment for haemophilus influenczae?

A

cephalosporin

Amox for mild cases

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15
Q

What is the treatment for legionella?

A

Macrolide or fluoroquinolone

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16
Q

What are the gram negative facultative anaerobes that cause pneumonia?

A 
Klebsiella
E.coli
Enterobacteria
Proteus
Serratia

(facultative anaerobes are for KEEPS)

17
Q

For which fungi does treatment require more than just Amp B (not including PCP)?

A

Blastomycosis
Coccidioidomycosis
Cryptococcus neoformans
Aspergillosis

18
Q

What is the treatment for blastomycosis?

A

Amp B + azoles

19
Q

What is the treatment for coccidioidomycosis?

A

Amp B + Azoles

20
Q

What is the treatment for cryptococcus neoformans?

A

Amp B + 5-fluorocytosine

21
Q

What is the treatment for aspergillosis?

A

Amp B
Azoles
Echinocandins

22
Q

What are the four bacteria that you cannot culture well?

A

Mycoplasm
Chlamydia
Legionella
TB

23
Q

What is the diagnostic method for mycoplasm?

A

Cold agglutination test

PCR/sergology

24
Q

Which bacteria can be diagnosed through the cold agglutination test?

A

Mycoplasm pneumoniae

25
Q

What is the diagnostic method for Chlamydia?

A

Microimmuno fluorescence

PCR

26
Q

What is the diagnostic method of choice for Legionella?

A

Direct fluorescence

Nucleic acid amplification

27
Q

What are the diagnostic tests for pertusis?

A

Culture

Nucleic acid amplification

28
Q

Can legionella spread from person to person?

29
Q

Why can you not use beta lactamases against legionella?

A

They have beta lactamases

Microbio (50 decks)

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