Reading Assignment Flashcards
What is the virus family of dengue virus? Enveloped? Genome?
Flaviviridae
+ssRNA
Enveloped
What is the virus family of yellow fever virus? Enveloped? Genome?
Flaviviridae
+ssRNA
Enveloped
What is the virus family of chikungunya virus? Enveloped? Genome?
Togaviridae
+ssRNA
Enveloped**
What is the virus family of colorado tick fever virus? Enveloped? Genome?
Reoviridae
dsRNA
Non-enveloped
What are the symptoms of dengue fever? (Initial, and later)
ILI
Maculopapular rash
Retro-orbital pain
1 week later, anorexia, malaise, weakness
Is dengue fatal? Is hemorrhagic?
Dengue = Rarely Hemorrhagic = 50%
What is the treatment for dengue fever?
Supportive
What are the symptoms of dengue hemorrhagic fever? (3)
- Hemorrhages and petechial rash
- Thrombocytopenia, hemoconcentration
- May evolve into shock
What is the treatment for DHF/DSS?
IVF and supportive
How do you diagnose dengue fever?
Serology
How is yellow fever transmitted?
Mosquitoes and monkeys
What are the two phases of symptoms for yellow fever (acute, and toxic)?
- ILI +backache
2. Rapid jaundice, hematemesis, hematochezia, renal failure
What is the prognosis for someone who develops Toxic yellow fever?
50% shot at death.
If survive, recovery without significant organ damage
How do you diagnose yellow fever?
Serology
What is the treatment for yellow fever?
IVF and support
How do you protect against yellow fever?
Vaccination
How is Chikungunya spread?
Mosquitoes
What are the symptoms of Chikungunya?
ILI
Severe arthralgias
What is the prognosis for Chikungunya?
Rarely fatal, but may developed recurrent bouts of arthralgias
How do you diagnose Chikungunya?
Serology
What is the treatment for CHIK V?
Supportive
Is there a vaccine for chikungunya?
Nope
What is the transmission vectors for Hantaviruses?
Inhalation of mice urine/excrement
What are the symptoms of hantavirus pulmonary syndrome?
Pulmonary edema like ARDS
What is the causative agent of hemorrhagic fever with renal syndrome?
Hantaviruses
What is the treatment for HPS?
Supportive
What is the vector for colorado tick fever virus?
Wood tick
What is the most common tick borne viral illness in the US?
Colorado tick fever
CTFV infects what cells?
Erythroid precursor cells
What are the symptoms of CTFV? (3)
biphasic fever (2-3 days)
ILI
Leukopenia
How does CTFV cause leukopenia?
possibly infects other hematopoietic precursor cells
What is the treatment for CTFV?
supportive
What is the family of ebola and marburg viruses? Genome? Enveloped?
Filoviridae
-ssRNA
Enveloped
How are ebola and marburg viruses spread?
human-human and human-monkey
How does Ebola/marburg spread?
Contact with blood or bodily fluids
What is the pathogenesis of Ebola/marburg virus?
rapid destruction of parenchymal cells of liver, lungs, spleen, and lymph nodes
What are the symptoms of Ebola/marburg virus?
ILI
Hemorrhagic disease
What is the prognosis for Ebola/marburg virus?
between 50-90% fatality
What is the treatment for ebola/marburg virus?
Supportive, quarantine, call the CDC
What are the symptoms associated with Arenaviruses?
Hemorrhagic
What is the vector for arenaviruses?
Rodents
What is the genome of arenaviruses? Enveloped?
-ssRNA
Enveloped
