Valvular Disorders & Heart Failure Flashcards

1
Q

How is cardiac output calculated?

A

Stoke volume x heart rate

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2
Q

What is cardiac output

A

The volume of blood the heart pumps in a minute

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3
Q

What units is cardiac output usually given in?

A

L/min

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4
Q

How is ejection fraction calculated?

A

(stroke volume/ end diastolic volume) x100

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5
Q

What is ejection fraction?

A

The volumetric fraction of blood ejected by the ventricle

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6
Q

What units is ejection fraction given in?

A

%

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7
Q

What are the 2 ways mean arterial pressure calculated?

A

Cardiac output x systemic vascular resistance + central venous pressure
OR
diastolic pressure + 1/3( systolic pressure- diastolic pressure)

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8
Q

What is mean arterial pressure?

A

Average arterial pressure through a single cardiac cycle

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9
Q

What are the units of mean arterial pressure?

A

mm Hg

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10
Q

What should mean arterial pressure be for there to be adequate perfusion?

A

65 mm Hg or above

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11
Q

Define infective endocarditis

A

Fever and new heart murmur

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12
Q

What is infective endocarditis?

A

Infection of the endocardium

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13
Q

What is the endocardium?

A

The innermost lining of the heart

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14
Q

How many layers are there in the lining of the heart? What are they called?

A

There are 3, from innermost to outermost they are:
Endocardium
Myocardium
Pericardium

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15
Q

What is the most common cause of infective endocarditis?

A

Streptococcus

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16
Q

How will patients with infective endocarditis present?

A

Fever, malaise, breathlessness, chest pain, fatigue, coughing (general signs of cardiac decomposition)

17
Q

What set of criteria are used to diagnose infective endocarditis?

A

Duke’s criteria

18
Q

What part of the heart does infective endocarditis most effect?

A

The left side and its valves (mitral and aortic) as this is where most blood flows

19
Q

How are IV drug users a concern in infective endocarditis?

A

They are at higher risk due to frequent intravenous injections- they may also present irregularly with more right sided problems as when injected, this is the first place bacteria in the blood will flow to

20
Q

What is dilated cardiomyopathy?

A

Dilation in the heart walls with impaired contractibility

21
Q

What are some complications of dilated cardiomyopathy?

A

Ventricular/atrial arrhythmias, sudden death, heart failure, impaired systolic and diastolic function

22
Q

What mutated genes are associated with dilated cardiomyopathy?

A

Mutations in genes encoding cardiac cytoskeletal proteins eg titin, lamin, phospholamban etc

23
Q

How is cardiac myopathy managed?

A

ACE inhibitors, beta blockers, diuretics for fluid overload, anticoagluation meds for atrial fibrillation, cardiac devices eg internal defribillator