Lower GI Tract Flashcards
What nerve innervates the ascending colon and most of the transverse colon in terms of parasympathetic supply?
Vagus nerve
What is distal parasympathetic supply from?
Pelvic nerves
What nerves give sympathetic supply to the lower GI tract
Lower thoracic and upper lumbar spinal cord
What is the external anal sphincter controlled by?
Somatic motor fibres in the pudendal nerves
What disease occurs when theres no enteric nervous system?
Hirschsprung’s
Where is the myenteric plexus ganglia concentrated?
Below the tenia coli
What are the 4 layers of the colon
Mucosa
Submucosa
Muscularis (made of 2 layers circular and longitudinal layers)
Serosa
Where does nerve supply to the lower GI tract come from?
Centrally AND from the submucosal and myenteric plexus (they are like localised pacemakers)
What does the mucosa layer contain? Why is this useful?
Lots of mucin producing glands to allow easy passage of stool and lubrications
What are the inflammatory lower GI tract disorders?
IBD and microscopic colitis
What are the infective lower GI tract disorders?
C diff
E coli
What are the structural lower GI tract disorders?
Diverticular disease
Haemorrhoids
Fissures
What are the functional lower GI tract disorders?
Irritable bowel syndrome
What are the neoplastic lower GI tract disorders?
Colonic polyps
Colon cancer
Who does IBD often affect?
Young people
What type of condition is IBD?
Lifelong, chronic and autoimmune
What is ulcerative colitis?
Inflammatory disorder limited to the colonic mucosa
What is the pattern of inflammation in UC?
Continuous