UWorld 1 Flashcards

1
Q

What would you suspect as a cause of macrocytic anemia in a pt w/ vitiligo or Hashimoto’s thyroiditis?

A

pernicious anemia

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2
Q

_______ is defined as the presence of Sx of schizophrenia along with mood Sx (major depression, bipolar disorder, or a mixed episode).

A

Schizoaffective disorder

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3
Q

_______ should be suspected in pts w/ blunt thoracic trauma who remain tachypneic and hypotensive despite aggressive fluid resuscitation. Classic X-ray findings reveal multiple rib fractures overlying a lung contusion.

A

Flail chest

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4
Q

What cranial injury causes a biconvex hematoma on CT?

A

epidural hematoma

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5
Q

What cranial injury appears as a uniconvex (semilenticular) hematoma on CT?

A

subdural hematoma

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6
Q

What are the most common sites of hypertensive intracerebral hemorrhage?

A

putamen and thalamus

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7
Q

What is the first-line drug for seizures in the emergency setting (e.g. status epilepticus)?

A

benzos (lorazepam)

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8
Q

What is the 2nd line Tx for seizures in the emergency setting?

A

phenytoin

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9
Q

What is the most common primary bone tumor affecting children and young adults?

A

osteosarcoma

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10
Q

What is the typical PE finding in osteosarcoma?

A

tender soft-tissue mass

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11
Q

What are the classic x-ray findings of osteosarcoma?

A

ssunburst pattern and Codman’s triangle (periosteal elevation)

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12
Q

What is the typical x-ray finding in Ewing’s sarcoma?

A

onion-skin periosteal rxn

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13
Q

Where does osteosarcoma usu occur generally? What specific 3 sites are seen most often?

A

metaphysis of long bones; distal femur, proximal tibia, proximal humerus

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14
Q

What will happen to methylmalonic acid levels in B12 def?

A

build up

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15
Q

What will happen to methylmalonic acid levels in B6 def?

A

no change

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16
Q

What substance will accumulate in the blood in both B6 and B12 def?

A

homocysteine

17
Q

_______ classically presents as a brawny, edematous, erythematous, cutaneous plaque w/ a “peau d’orange” appearance overlying a breast mass.

A

Inflammatory breast carcinoma

18
Q

What is the most vcommon cause of hypercalcemia in ambulatory pts?

A

primary hyperparathyroidism

19
Q

What is the most common cause of primary hyperparathyroidism?

A

parathyroid adenoma

20
Q

Indomethacin and hydrochlorothiazide are used in the Tx of what kind of diabetes insipidus?

A

nephrogenic

21
Q

A holosystolic murmur at the lower sternum that increases w/ inspiration is most likely _______.

A

tricuspid regurgitation

22
Q

What antibiotic should be used as empiric tx for endocarditis in an IV drug abuser?

A

vancomycin

23
Q

What is the most common cause of hypercalcemia in hospitalized pts?

A

malignancy, of course

24
Q

How does sarcoidosis cause increased serum calcium levels?

A

increased conversion of 25-OH vit D to 1,25-OH vit D in granulation tissue

25
Q

For a pt w/ 0-1 risk factors for coronary artery disease, what is the LDL cutoff for starting medication?

A

190 mg/dL