6/14/13 b Flashcards
What property of atypical antipsychotics accounts for their ability to combat the negative Sx of schizophrenia and reduced extrapyramidal effects?
blockade of 5-HT receptors
Sudden onset of sharply demarcated, red, edematous, tender skin lesion w/ raised borders accompanied by fever suggests _______.
erysipelas
What is the most common causative organism of erysipelas?
GAS
Which antibody is ulcerative colitis associated with?
p-ANCA
What Ab is assoc’ed w/ subacute cutaneous lupus erythematosis and neonatal lupus, esp. when assoc’ed w/ congenital heart block?
anti-Ro
Which antithyroid drug is preferred durng preg?
PTU
If a woman will have a subtotal thyroidectomy during preg, when should it be done?
2nd trimester
Which is the hearing test in which the tuning frk is placed in the middle of the forehead?
Weber
Which is the hearing test in which the tuning fork is placed on the mastoid process and then held next to the ear?
Rinne
What syndrome may feature a glucagonoma?
MEN-1
What happens in Zollinger-Ellison syndrome?
gastrinoma causes many peptic ulcers
What causes hyponatremia w/ a high fractional excretion of Na+ in a pt w/ recent brain trauma or a major CNS procedure?
SIADH
What is the usu tx of SIADH?
fluid restriction and furosemide
For SIADH, what can be used in addition to fluid restriction and loop diuretics for more aggressive tx or in those who cannot take more fluid loss?
ADH antagonists
Name 2 ADH antagonists.
demeclocycline, and Li
Anti-DNAse B and anti-hyaluronidase are Abs against what organism?
group A Strep
What are the 5 major Jones criteria for Dx of rheumatic fever.
Joints (migratory polyarthritis) O-shaped heart (carditis) Nodules, subcutaneous Erythema marginatum Sydenham's chorea
Describe the rash of erythema marginatum.
serpiginous red macules w/ pale centers, non-pruritic (spares the face)
What electrocardiographic abnormality may be found in rheumatic fever?
prolonged PR interval
An AIDS pt presenting w/ odynophagia should be empirically treated for _______.
Candida
If empiric tx for odynophagia in an AIDS pt fails, what is the next step?
endoscopy
What do esophageal ulcers caused by HSV look like grossly?
small and volcano-like
What do esophageal ulcers of CMV look like grossly?
large and deep
