5/29/13 Flashcards

1
Q

If a breast lesion in an older patient is suspicious on mammogram, and FNA is negative, what is the next step?

A

get tissue! (Core biopsy or lumpectomy) FNA is not definitive unless (+)!

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2
Q

_______ is a paraneoplastic (or primary) process usu. assoc. w/ bronchogenic carcinoma. It is characterized by bone pain, clubbing, synovial effusions, and periostosis of the tubular bones.

A

Hypertrophic pulmonary osteoarthropathy (HPOA)

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3
Q

What is the best initial test to investigate for a primary lung lesion, e.g. in HPOA?

A

CXR

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4
Q

The PTT time reflects the activity or nearly all clotting factors except ___ and XII.

A

VII

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5
Q

Which coagulation study is used to measure the effectiveness of heparin?

A

PTT

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6
Q

Which coagulation study is used to measure the activity of warfarin?

A

PT/INR

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7
Q

Which coagulation study, PT or PTT, does NOT take factor VII into account?

A

aPTT

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8
Q

When is angina stable?

A

when it is only induced by activity

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9
Q

Eosinophilic inclusions in the substantia nigra are seen in what disease?

A

Lewy body dementia

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10
Q

How is Lewy body dementia clinically different from Parkinson’s with dementia?

A

onset of dementia is concurrent w/ motor Sx (not a year later)

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11
Q

What is the tx for anorexia nervosa (in a stable pt)?

A

behaviorally-based psychotherapy (e.g. CBT)

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12
Q

Baby w/ chronic constipation and distended abdomen. Rectal exam results in explosive espulsion of hard stool and flatus and relieves the abd distention. Dx?

A

Hirschsprung’s disease

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13
Q

What is the best initial test for Hirschsprung’s disease?

A

anorectal manometry

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14
Q

What is the connfirmatory test for Hirschsprung’s disease?

A

full-thickness biopsy of rectal mucosa

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15
Q

What will happen to tactile fremitus in lung parenchymal consolidation?

A

increase

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16
Q

What will happen to tactile fremitus in leural effusion?

A

decrease

17
Q

What is the normal fraction of inspired oxygen (FiO2)?

A

21%

18
Q

So what is the normal PaO2/FiO2 (approx.)?

A

500

19
Q

What is the mechanism of decreased pigmentation in oculocutaneous albinism?

A

defective production of melanin form Tyr

20
Q

What is the mechanism of depigmentation in vitiligo?

A

autoimmune destruction of melanocytes