5/24/13 Flashcards

1
Q

If a pt appears to have diabetes insipdus (i.e. water deprivation test showed no increase in urine osmolality) what is the test to determiine if central of nephrogenic?

A

intranasal or SQ desmopressin

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2
Q

What is the effect of diabetes insipidus (not psychogenic polydipsia) on serum Na+?

A

increase

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3
Q

What is the best Tx for sick sinus syndrome?

A

ventricular pacemaker

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4
Q

What is the other name for IGF-1?

A

somatomedin-C

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5
Q

What endocrine disorder might you consider in a pt w/ bilateral carpal tunnel syndrme?

A

acromegaly

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6
Q

What is the FIRST step in the workup for acromegaly?

A

serum IGF-1

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7
Q

If IGF-1 is hi in a pt suspected of acromegaly, what is step #2?

A

oral glucose tolerance test

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8
Q

If oral glucose tolerance test ixs positive in pt w/ suspected acromegaly, what is step #3?

A

CT or MRI of head for macroadenoma

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9
Q

What are the first 3 lines of tx for acromegaly (if amcroadenoma) in order?

A
  1. surgical
  2. medical
  3. radiation
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10
Q

What, in particluar, is elevated in the blood in Paget’s disease of the bone?

A

alk phos

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11
Q

What, in partticular, is elevated in the urine in Paget’s disease of the bone?

A

hydroxyproline

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12
Q

What is the best first test for paget’s disease of the bone?

A

radiologic bone scan

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13
Q

What would be seen oin bone scan in Paget’s disease of te bone?

A

lytic lesions

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14
Q

What is always the tx for symptmatic Paget’s disease of the bone?

A

bisphosphonates

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15
Q

What the hell is amlodipine again?

A

artery-selective Ca++ channel blocker

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16
Q

What is a rapidly growing keratotic lesion often described as “crateriform” or “volcano-like”?

A

keratoacanthoma

17
Q

An opening snap followed by a low-pitched diastolic rumble is characteristic of what valvulopathy?

A

mitral stenosis

18
Q

How does the length of time between A2 and the opening snap of mitral stenosis relate to the severity of the stenosis?

A

inversely

19
Q

Why does the opening snap of mitral stenosis occur earlier when the disease is more severe?

A

pressure biulds up in the LA

20
Q

What conditions could cause a widely split S2?

A

RV volume overload or pulm htn