6/14/13 a (RTA, MI localization)

Question 1

What is the pathophysiological defect in RTA type 2?

Answer 1

inability to reabsorb bicarb in proximal tubule

Question 2

Is the urine acidic or basic in RTA type 2 (after a little while)? Why?

Answer 2

acidic; body runs out of bicarb

Question 3

What is the diagnostic test for RTA type 2?

Answer 3

give bicarb

Question 4

What is the result of giving bicarb to a person who has RTA type 2?

Answer 4

urine becomes basic and blood remains acidotic

Question 5

What are the clinical features of RTA type 2?

Answer 5

osteomalacia/rickets

Question 6

How does RTA type 2 cause osteomalacia?

Answer 6

acidotic urine frees Ca+ from bones

Question 7

What is the Tx for RTA type 2?

Answer 7

bicarb and thiazide

Question 8

What is the pathophysiological defect in RTA type 4?

Answer 8

aldo deficiency

Question 9

What lab abnormality distinguishes RTA type 4 from 1 and 2?

Answer 9

hi K+

Question 10

What is the Tx for RTA type 4?

Answer 10

fludrocortisone

Question 11

Why is the anion gap normal in all forms of RTA?

Answer 11

hi serum Cl-

Question 12

A normal anion gap metabolic acidosis must either be RTA or _______.

Answer 12

diarrhea

Question 13

What should be done for a recurrent chalazion?

Answer 13

istologic exam to rule out malignancy

Question 14

What 2 kinds of cancer can masquerade as a recurrent chalazion (obstruction of the meibomian gland)?

Answer 14

meibomian gland carcinoma and BCC

Question 15

What kind of pancreatic endocrine tumor causes watery diarrhea and hypokalemia?

Answer 15

VIPoma

Question 16

What medication can help control the diarrhea of a VIPoma?

Answer 16

octreotide

Question 17

What pancreatic endocrine tumor presents w/ necrotizing dermatitis, wt. los, anemai, and persistent hyperglycemia?

Answer 17

glucagonoma

Question 18

Pts w/ carcinoid syndrome are most at risk of developing what vitamin deficiency?

Answer 18

niacin

Question 19

Why does carcinoid syndrome cause niacin deficiency?

Answer 19

tryptophan is diverted to serotonin synthesis

Question 20

ST depression in leads V1 and V2 suggest an MI in what region?

Answer 20

posterior wall

Question 21

Which coronary vessel is usu occluded in inf. wall MI?

Answer 21

RCA

Question 22

What vessel aside from the RCA could cause an nferior wall MI?

Answer 22

LCX

Question 23

ST elevation in leads V1-V4 indicates an MI in which region?

Answer 23

septal

Question 24

What vessel is occluded in an anterior septal myocardial infarction?

Answer 24

LAD