5/25/13 Flashcards

1
Q

How long must Sx have been occurring to Dx dysthymic or cyclothymic disorder?

A

2 yrs

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2
Q

Wherein lies the defect in Alport’s syndrome?

A

type IV collagen

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3
Q

What is the best first step in diagnosing Alport’s syndrome?

A

skin biopsy and immunohistochemical analysis

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4
Q

How is a Dx of Alport’s syndrome confirmed?

A

kidney biopsy

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5
Q

What is the characteristic finding on renal biopsy in Alport’s syndrome?

A

splitting of the glomerular BM

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6
Q

What iss usually the first clinical manifestation of Alport’s syndrome?

A

microscopic hematuria

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7
Q

What is the usual inheritance pattern for Alport’s syndrome?

A

X-linked

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8
Q

An optimal Pap smear is taken from what part of the cervix?

A

transformation zone

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9
Q

What bacteria are most commonly isolated from cat bite wounds?>

A

Pasteurella multocida and S. aureus

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10
Q

What is the first line treatment for cat bite wounds?

A

Amoxicillin-clavulanate

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11
Q

Are fasciculations an upper or lower motor neuron lesion finding?

A

lower

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12
Q

What studies can be used to confirm a Dx of ALS?

A

nerve conmduction and emlectromyography

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13
Q

What is the only drug with any proven efficacy for treating ALS?

A

Riluzole

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14
Q

Which occurs first in ALS, proximal or distal muscle weakness?

A

distal

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15
Q

Whch occurs first in myasthenia gravis, proximal or distal muscle weakness?

A

proximal

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16
Q

Is polymyositis mainly proximal or distal muscle weakness?

A

Proximal!

17
Q

Is polyneuropathy upper motor neuron, lower, or both?

A

lower

18
Q

Where in the spinal cord are the lower motor neurons’ cell bodies located?

A

anterior horn

19
Q

Abdominal angina, arthritis, and skin nodules/ulceration on a background of constitutionalSx is highly suggestive of _______.

A

Polyarteritis nodosa (PAN)

20
Q

What infection is polyarteritis nodosa associated with in up to 50% of cases?

A

HBV