5/25/13 Flashcards
How long must Sx have been occurring to Dx dysthymic or cyclothymic disorder?
2 yrs
Wherein lies the defect in Alport’s syndrome?
type IV collagen
What is the best first step in diagnosing Alport’s syndrome?
skin biopsy and immunohistochemical analysis
How is a Dx of Alport’s syndrome confirmed?
kidney biopsy
What is the characteristic finding on renal biopsy in Alport’s syndrome?
splitting of the glomerular BM
What iss usually the first clinical manifestation of Alport’s syndrome?
microscopic hematuria
What is the usual inheritance pattern for Alport’s syndrome?
X-linked
An optimal Pap smear is taken from what part of the cervix?
transformation zone
What bacteria are most commonly isolated from cat bite wounds?>
Pasteurella multocida and S. aureus
What is the first line treatment for cat bite wounds?
Amoxicillin-clavulanate
Are fasciculations an upper or lower motor neuron lesion finding?
lower
What studies can be used to confirm a Dx of ALS?
nerve conmduction and emlectromyography
What is the only drug with any proven efficacy for treating ALS?
Riluzole
Which occurs first in ALS, proximal or distal muscle weakness?
distal
Whch occurs first in myasthenia gravis, proximal or distal muscle weakness?
proximal
Is polymyositis mainly proximal or distal muscle weakness?
Proximal!
Is polyneuropathy upper motor neuron, lower, or both?
lower
Where in the spinal cord are the lower motor neurons’ cell bodies located?
anterior horn
Abdominal angina, arthritis, and skin nodules/ulceration on a background of constitutionalSx is highly suggestive of _______.
Polyarteritis nodosa (PAN)
What infection is polyarteritis nodosa associated with in up to 50% of cases?
HBV
