6/21/13 a

Question 1

What is the syndrome when a person has 3 family members w/ colon cancer over 2 generations, one of whom had it before the age of 50?

Answer 1

HNPCC (Lynch syndrome)

Question 2

When should people w/ HNPCC start colonoscopy?

Answer 2

25 yo

Question 3

How often should people w/ HNPCC get a colonoscopy?

Answer 3

q 1-2 yrs

Question 4

What kind of colon polyps are found in juvenile polyposis?

Answer 4

hamartomas

Question 5

What is seen on the lips of kids w/ Peutz-Jaeghers syndrome?

Answer 5

melanotic spots

Question 6

When should people with FAP start colonoscopies? How often?

Answer 6

12 yo; q 1-2 yrs

Question 7

What differentiates Gardner’s syndrome from the otrher collon tumor syndromes?

Answer 7

osteomas and soft tissue tumors

Question 8

What differentiates Turcot’s from the other colon tumor syndromes?

Answer 8

CNS tumors

Question 9

Which kind of leukemia will have a positive α-naphthyl esterase?

Answer 9

Acute MONOCYTIC leukemia (FAB M5)

Question 10

What is unique about the clinical presentation of acute monocytic leukemia?

Answer 10

rapid onset w/ bleeding from gums/nose and gingival hyperplasia

Question 11

What is the IV fluid of choice for moderate to severe hypovolemic hypernatremia?

Answer 11

normal saline

Question 12

what is the iv fluid of choice for hypervolemic hypernatremia?

Answer 12

d5w

Question 13

Intravascular hemolytic anemia + hepatic vein thrombosis =

Answer 13

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Question 14

What is the molecular defect/mech in paroxysmal nocturnal hemoglobinuria?

Answer 14

no GP1 anchor protein –> RBC destruction by complement

Question 15

How would acute angle-closure glaucoma present?

Answer 15

sudden onset eye pain, photophobia, redness, vision loss, and non-reactive pupil

Question 16

Would an infarction affecting the optic nerve be painful?

Answer 16

no

Question 17

What is the best Dx test for acute angle-closure glaucoma?

Answer 17

tonometry

Question 18

cardiogenic pulmonary edema in the setting of longstanding htn is likely d/t _______.

Answer 18

LV diastolic dysfunction

Question 19

What medication will act quickly to relieve dyspnea in a pt w/ LV hypertrophy and diastolic dysfunction?

Answer 19

nitroglycerin

Question 20

What condition is assoc’ed w/ “bones, stones, abdominal groans, and psychic moans”, as well as htn?

Answer 20

primary hyperparathyroidism