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STEP II > More Liver and Gastro > Flashcards

More Liver and Gastro Flashcards

Liver, Dumping Syndrome, and IBD

1
Q

What are the results of iron studies in pts w/ hemochromatosis: Fe, ferritin, TIBC?

A

Fe up
ferritin up
TIBC down

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2
Q

How do you treat hemochromatosis pts who overabsorb iron?

A

phlebotomy

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3
Q

How do you treat pts w/ hemochromatosis who have been over-transfused?

A

deferoxamine

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4
Q

Cirrhosis + choreiform movement + psyhcosis

A

Wilson disease

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5
Q

What is the tx for Wilson’s disease?

A

penicillamine

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6
Q

What are the 3 tx options for chronic HBV?

A

interferon OR lamivudine OR adefovir

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7
Q

What is the tx of chronic HCV?

A

interferon + ribavirin

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8
Q

What is the first test to used to confirm suspected Wilson’s disease?

A

serum ceruloplasmin

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9
Q

What other common complication of longstanding diabetes has a similar pathophysiology to diabetic gastroparesis?

A

peripheral neuropathy

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10
Q

What is the primary stimulant of gastrin release?

A

distention

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11
Q

What 2 drugs are used for the Tx of diabetic gastroparesis?

A

Erythromycin and Metoclopramide

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12
Q

What class of Abx does erythromycin belong to?

A

macrolides

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13
Q

What ECG abnormality can macrolides cause?

A

Prolonged QT interval

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14
Q

Metoclopramide is both a prokinetic and a(n) _______.

A

anti-emetic

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15
Q

What 2 things cause dizziness, sweating in dumping syndrome?

A

hypoglycemia and intravascular volume depletion

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16
Q

Whish type of IBD is ANCA+?

A

UC

17
Q

Which type of IBD is ASCA+?

A

Crohns

18
Q

Name 3 adverse effects of sulfasalazine (for the 10-30% of the population w/ sulfa sensitivity).

A

rash, hemolysis, and renal problems

19
Q

What specific renal problem does sulfasalazine cause?

A

Allergic Interstitial Nephritis

20
Q

What steroid is used for acute exacerbations of IBD?

A

Budesonide

21
Q

Why is budesonide the steroid of choice for IBD exacerbations?

A

highly susceptible to first-pass effect –> no systemic efftects!

22
Q

The first line drugs for chronic IBD are all derivatives of what?

A

mesalamine

23
Q

The 3 main mesalamine-based drugs for IBD all have what 3 letters in their names?

A

ASA - Pentasa (or 5-ASA), AsaCol, and Rowasa

24
Q

What 2 other immunomodulant drugs (not mesalamine) are used chronically for IBD?

A

6-MP, azothioprine

25
Q

What Abx are used to prevent perirectal/perianal disease in Crohns?

A

Vanco, metro

STEP II (79 decks)

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