5/25/13 b Flashcards
is the acidosis of renal tubular acidosis anion gap or non-anion gap?
non-anion gap
Which type of renal tubular acidosis causes hyperkalemia?
type IV
What is the mechanism of RTA type IV at the level of the glomerulus?
lack of or insensitivity to Aldo at collecting duct
What are 2 endocrine diseases and 2 drugs that cause RTA type IV?
Addison’s, DM (nephropathy), spironolactone, ACE-I’s
What aldo like substance can be given to treat RTA type IV?
fludrocortisone
What 2 other things should be administered w/ fludrocortisone to tx RTA type IV?
NaHCO3 and furosemide
What is the mech (glomerular level) of RTA type 2?
reduced proximal tubular bicarb resorption
What are the 2 most common causes of RTA type 2?
multiple myeloma and carbonic anhydrase inhibitor
How does multiple myeloma cause RTA type 2?
increased excretion of Ig light chains
What is euthyroid sick syndrome?
low T4 and T3 in seriously ill pts, but normal TSH
What are 2 ways euthyroid sick syndrome can be told apart from true hypothyroidism?
normal TSH; disproportionately low T3
What is an apparent claudication of the legs that is relieved by sitting and/or leaning forward?
Lumbar spinal stenosis
What structure is compressed in lumbar spinal stenosis?
spinal nerve roots
What do you call a common low-back pain in older pts - simple low-back pains and sprains - w/ muscle spasm that occasionally radiates to the buttocks?
Lumbago
Low-back pain of what etiology usu. worsens when the lumbar flexion?
herniated disc
