Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Histology Pt. 2 > Unit 2 - Adrenal Gland > Flashcards

Unit 2 - Adrenal Gland Flashcards

1
Q

What are the layers of the cortex of the adrenal gland?

A

zona glomerulosa, zona fasciculata, zona reticularis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What hormone does zona glomerulosa secrete?

A

aldosterone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What hormone does zona fasciculata secrete?

A

cortisol and cortisone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What hormone does zona reticularis secrete?

A

androstenedione, testosterone, and estradiol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What hormones does the medulla secrete?

A

catecholamines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What layers of the adrenal cortex are under ACTH control?

A

zona fasciculata and zona glomerulosa (little effect)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the precursor for the biosynthesis of hormones of the adrenal cortex?

A

Cholesterol which is regulated by ACTH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the effects of cortisol on the intermediary metabolism?

A

they are opposite the effect of insulin and it potentiates (increases) the effects of glucagon, epinephrine and GH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the major effects of cortisol on the anterior pituitary?

A

decrease ADH, TSH, and GH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the major effects of cortisol on connective tissue?

A

decreased collagen synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the major effectsof cortisol on the GI tract?

A

decreased mucosal barrier, ulcer formation, decreased Ca absorption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the major effects of cortisol on the fetus?

A

prepares the fetus organ systems for birth and triggers parturiton

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the major effects of cortisol on the inflammatory and immune system?

A

decreased inflammatory and immune response - limit destruction of normal tissue during injury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the major effects of cortisol on bone?

A

decrease in calcium deposition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is Cushing’s disease?

A

pituitary dependent hyperadrenocorticism - excessive ACTH decretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What species are you most likely to see cushings in?

A

horses and dogs

17
Q

What is Cushing’s disease also known as in horses?

A

Equine PPID - pituitary pars intermedia dysfunction

18
Q

What are the mechanisms that lead to Equine PPID?

A

the cells in the pars intermedia lose hypothalamic dopaminergic inhibition leading to an increase in ACTH release

19
Q

What is the treatment for Cushing’s disease in horses?

A

dopamine agonists

20
Q

What are common symptoms associated with PPID?

A

PU/PD, hirsutism, laminitis

21
Q

What are the treatments for Cushings disease in dogs?

A

The primary one is mitotane and the second is trilostane

22
Q

What does mitotane do?

A

it is used for controlled destruction of the adrenal cortex

23
Q

What does trilostane do?

A

it blocks cortisol synthesis

Histology Pt. 2 (52 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions