Male Repro 2 Flashcards

1
Q

What is the difference between between a musculovascular and fibroelastic penises?

A

musculovascular penises enlarge in length and diamater during tumescene whereas fibroelastic penises are sigmoidal shaped that extend only in length during tumescence

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2
Q

What is the urethral process?

A

an extension of the urethra that extends beyond the length of the penis in the ram and the buck

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3
Q

What is the function of the urethral process?

A

it is possibly a mechanism to propel sperm deeper into the female reproductive tract

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4
Q

Why can the urethral process be problematic?

A

because it can get stones trapped in it

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5
Q

What is corpus cavernosum?

A

erectile tissue of the penis

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6
Q

What is the corpus spongiosum?

A

spongy area that surrounds the urethra and prevents occlusion of the urethra during tumescence

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7
Q

What is nitric oxides role in tumescence?

A

it causes dilation of the helicine artery which allows blood to move through the loosened interendothelial junctions

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8
Q

What is nitric oxide released from in tumescence?

A

it is released by non-adrenergic/non-cholinergic neurons from the parasympathetic system

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9
Q

What biochemical basis allows for detumescence to occur?

A

phosphodiesterase 5 recycles cGMP to GMP thus halting tumescence by returning the vascular smooth muscle to its contracted state

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10
Q

What is the vascular basis of detumescence?

A

once the vascular smooth muscle ccontracts, blood from the helicine artery leaves the corpus cavernosum and the penis drains

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11
Q

What autonomic system is tumescence driven by and how does it work?

A

the parasympathetic division involving the release of norepinephrine that relaxes the vascular smooth muscle of the helicine artery in the penis

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12
Q

What autonomic system is ejaculation driven by and how does it work?

A

the sympathetic system that promotes the release of mucus and the coordinated contraction of the epididymis, vas deferens, and urethra

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13
Q

What autonomic system is demutescence run by?

A

the sympathetic system

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14
Q

What hypothalamic peptide is the central regulator of male reproductive physiology?

A

GnRH

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15
Q

What are the two anterior pituitary hormones that regulate male reproductive physiology?

A

LH and FSH

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16
Q

What is the function of LH in male reproductive physiology?

A

it synthesizes testosterone in the leydig cells

17
Q

What is the function of FSH in male reproductive physiology?

A

it stimulates spermatogenesis in the sertoli cells by promoting the elevation of the spermatocytes towards the lumen of the seminiferous tubules

18
Q

What is the negative regulator of the male reproductive physiologic hormones?

A

inhibin

19
Q

What is the role of inhibin in male reproductive physiology?

A

it activates its receptor and promotes the synthesis of proteins that trap FSH in the anterior pituitary cells or GnRH in the hypothalamus

20
Q

What does inhibin come from?

A

sertoli cells

21
Q

Why does testosterone interact with an intracellular receptor while other hormones interact with receptors that extend outside of the cell?

A

because testosterone is lipid-soluble so it can cross biological membranes and interact with its intracellular receptor

22
Q

What is the os penis?

A

a bone in the penis in the dog, cat, and non-human primates that aid in maintaining tumescence

23
Q

What is the bulbus glandis?

A

a portion of the penis in the dog that enlarges during coitus which helps maintain the ineraction with the female

24
Q

Why is cancer a side effect of anabolic steroids that mimic testosterone?

A

because it upregulates specific gene expression in genes that encode for proteins that promote hyperplasia