thyroid/parathyroid Flashcards
what is the function hormone of the thyroid?
TH
what controls TH
TSH
T3 is ____ times more potent than T4
five
what are some things that thyroid hormone does?
-increase BMR
-increase growth
-stimulate protein synthesis
-INSULIN ANTAGONIST
what is secreted in response to high calcium levels
calcitonin
what increses calcium deposition in bone
calcitonin
enlargement of thyroid gland
goiter
what is primary hypothyroidism called?
Hashimoto’s
what classifies primary hypothyroidism
no TSH responding
what is hyperthyroidism called?
grave’s disease
what happens when antibodies want to sit on receptors and make lots of hormones
hyperthyroidism (graves)
what is an extreme complication of hyperthyroidism
thyroid storm (thyrotoxicosis)
inspection and palpation involving thyroid glands
throat thickening (swallow), breathing, size, symmetrical, tender
which thyroid test is an accurate indicator of thyroid problems
T3 resin uptake
what measures rate of idoine
radioactive iodine uptake
what does a fine needle aspiration biopsy do?
look for cancer
patho of secondary hypothyroid
inc. TRH -> dec. TSH = dec. T3 T4
what are some meds that affect thyroid testing
-amiodarone
-aspirin
-cimetidine
-estrogens
-furosemide
-glucocorticoids
-heparin
-lithium
-phenytoin
what is deficiency of TH
hypothyroidism
characteristics of hypothyroidism
-slowed metabolism
-decreased heat production
-decreased oxygen consumption by tissues
what is primary hypothyroidism
-autoimmune thyroiditis (hashimoto)
-95% of cases
-involves actual gland
what is secondary hypothyroidism
-overtreatment of hyperthyroidism
-thyroidectomy (replace hormones)
-radioactive iodine
-something else causes it, not a gland problem
clinical manifestations / symptoms of hypothyroidism
-intolerance to cold
-dry skin
-hair loss
-anorexia
-lethargy
-muscle cramps/wekaness
-apathy
-facial/eyelid edema
-blank expression
-brittle nails and hair
what is a major problem from hypothyroidism
myxedema
describe myxedema
-elevated cholesterol
-life threatening and rare
-undiagnosed/undertreated
-can be exacerbated
what other complications come from myxedema?
-hyponatremia
-hypercalcemia
-hypoglycemia
-water intoxication
-hypoventilation
what are some symptoms of myxedema?
depression, diminished cognitive status, lethargy, and somnolence
which symptoms of myxedema are life threatening and require intensive support
-hyponatremia
-hypoglycemia
-hypoventilation
-hypotension
-bradycardia
-hyponatremia
-CV collapse
-shock
pharmacologic therapy for hypothyroidism
levothyroxine (replacing TH, not TSH)
how do you manage hypothyroidism?
administer thyroid hormone
what are interventions for myxedema?
ventilation, control co2, maintain vs, not too much fluid
what do hypothyroidism meds effect and what kind if effects
-increase warfarin effectiveness
-CV effects of adrenergic agents
what does graves disease (hyperthyroidism) have?
toxic, difffuse, goiter
three hallmarks of hyperthyroidism (graves)
goiter, hyperthyroidism, exopthalmos
average age of graves (hyperthyroidism)
-
hat antibodies are made in graves disease?
IgG antibodies
what is hyoerthyroidism
excess thyroid hormone (grave’s)
what are common forms of hyperthyroidism
-toxic multinodular goiter
-toxic adenoma
-thyroiditis
-grave’s
clinical manifestations (signs) of hyperthyroidism
-intolerance to heat
-oily skin
-weight loss
-bulging eyes
-tachycardia
-breast enlargement
-inc. systolic
-tremors
-clubbing
complications of hyperthyroidism
-exopthalmos
-heart disease
-thyroid storm
what are other names for thyroid storm
thyroid crisis
thyroid toxicosis
what is medical management for hyperthyroidism
-anti-thyroid meds
-SSKI (lugols solution)
-radioactive iodine
-thyroidectomy
what are antithyroid meds?
PTU and methimazole (tapazole)
nursing interventions for hyperthyroidism
-maintain high calorie high protein
-daily weight
-maintain cardiac output
enlargement of the thyroid gland after swallowing/breathing
goiter
where do goiters come from
hypothyroidism or hyperthyroidism
are goiters malignant
could be either
types of goiters
-endemic (iodine deficient)
-nodular
what are endemic goiters and where do they come from?
-iodine deficient
-from hypothyroidism
what is a nodular goiter
-benign but can turn malignant
-from hyperthyroidism
risk factors for thyroid tumors
-external radiation
-smoking
-sedentary
-unhealthy eating
-high stress
pre-op care fro thyroid cancer
CBC, anemia, calcium, thyroid level, what to expect, yankaur
post op care for thyroid cancer
-inc. HOB for edema, dont move head (sandbags), look for blood behind head, monitor complications
what is important to monitor after a thyroidectomy
calcium
how many parathyroid glands are there?
4, up to 12
what does PTH do
regulate calcium
secondary hyperparathyroidism causes _______
increased clacium in blood
over activity of one or more parathyroid glands
hyperparathyroidism
excess parathyroid hormone = ______
increased serum calcium
what can hyperparathyroidism lead to?
-inc. calcium (in blood)
-bone decalcification (pulled from bone)
-renal calculi
how old are hyperparathyroid patients
> 60
s/sx hyperparathyroidism
-anorexia
-n/v
-constipation
-abd pain, bone pain
-bone cysts
-dysrhythmias
-fatigue
what is a complication of hyperparathyroidism?
hypercalcemic crisis
what levels classify hypercalcemic crisis?
> 13 mg/dl
what do pts with hyperparathyroidism need
rapid rehydration (calcitonin)
medical management of hyperparathyroidism
-surgical removal (hypoparathyroidism)
-hydration therapy
-mobility
-diet and meds
what meds are used in hyperparathyroidism
calcium chelators
phosphates
calcitonin
nursing care for hyperparathyroidism
monitor for stones
VS
strain urine
limit fluids with calcium
what are causes of hypoparathyroidism
-iatrogenic (treatment-induced)
-idiopathic (unknown)
s/sx of hypoparathyroidism
n/t
cramps
spasms
seizures
mental changes
muscle contractions
chvostek (facial) and trousseau (wrist/hand)
complications of hypoparathyroidism
-respiratory obstruction (spasms)
-calcification of eyes/basal ganglia
hoe to diagnose hypoparathyroidism
EEG, labs (PTH), CT
in hypoparathyroidism, focus on correcting…
-hypocalcemia (replace magnesium) CALCIUM GLUCONATE!
-vit. D deficiency
-hypomagnesemia