thyroid/parathyroid Flashcards
what is the function hormone of the thyroid?
TH
what controls TH
TSH
T3 is ____ times more potent than T4
five
what are some things that thyroid hormone does?
-increase BMR
-increase growth
-stimulate protein synthesis
-INSULIN ANTAGONIST
what is secreted in response to high calcium levels
calcitonin
what increses calcium deposition in bone
calcitonin
enlargement of thyroid gland
goiter
what is primary hypothyroidism called?
Hashimoto’s
what classifies primary hypothyroidism
no TSH responding
what is hyperthyroidism called?
grave’s disease
what happens when antibodies want to sit on receptors and make lots of hormones
hyperthyroidism (graves)
what is an extreme complication of hyperthyroidism
thyroid storm (thyrotoxicosis)
inspection and palpation involving thyroid glands
throat thickening (swallow), breathing, size, symmetrical, tender
which thyroid test is an accurate indicator of thyroid problems
T3 resin uptake
what measures rate of idoine
radioactive iodine uptake
what does a fine needle aspiration biopsy do?
look for cancer
patho of secondary hypothyroid
inc. TRH -> dec. TSH = dec. T3 T4
what are some meds that affect thyroid testing
-amiodarone
-aspirin
-cimetidine
-estrogens
-furosemide
-glucocorticoids
-heparin
-lithium
-phenytoin
what is deficiency of TH
hypothyroidism
characteristics of hypothyroidism
-slowed metabolism
-decreased heat production
-decreased oxygen consumption by tissues
what is primary hypothyroidism
-autoimmune thyroiditis (hashimoto)
-95% of cases
-involves actual gland
what is secondary hypothyroidism
-overtreatment of hyperthyroidism
-thyroidectomy (replace hormones)
-radioactive iodine
-something else causes it, not a gland problem
clinical manifestations / symptoms of hypothyroidism
-intolerance to cold
-dry skin
-hair loss
-anorexia
-lethargy
-muscle cramps/wekaness
-apathy
-facial/eyelid edema
-blank expression
-brittle nails and hair
what is a major problem from hypothyroidism
myxedema
describe myxedema
-elevated cholesterol
-life threatening and rare
-undiagnosed/undertreated
-can be exacerbated
what other complications come from myxedema?
-hyponatremia
-hypercalcemia
-hypoglycemia
-water intoxication
-hypoventilation
what are some symptoms of myxedema?
depression, diminished cognitive status, lethargy, and somnolence
which symptoms of myxedema are life threatening and require intensive support
-hyponatremia
-hypoglycemia
-hypoventilation
-hypotension
-bradycardia
-hyponatremia
-CV collapse
-shock
pharmacologic therapy for hypothyroidism
levothyroxine (replacing TH, not TSH)