thyroid/parathyroid Flashcards

1
Q

what is the function hormone of the thyroid?

A

TH

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2
Q

what controls TH

A

TSH

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3
Q

T3 is ____ times more potent than T4

A

five

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4
Q

what are some things that thyroid hormone does?

A

-increase BMR
-increase growth
-stimulate protein synthesis
-INSULIN ANTAGONIST

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5
Q

what is secreted in response to high calcium levels

A

calcitonin

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6
Q

what increses calcium deposition in bone

A

calcitonin

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7
Q

enlargement of thyroid gland

A

goiter

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8
Q

what is primary hypothyroidism called?

A

Hashimoto’s

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9
Q

what classifies primary hypothyroidism

A

no TSH responding

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10
Q

what is hyperthyroidism called?

A

grave’s disease

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11
Q

what happens when antibodies want to sit on receptors and make lots of hormones

A

hyperthyroidism (graves)

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12
Q

what is an extreme complication of hyperthyroidism

A

thyroid storm (thyrotoxicosis)

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13
Q

inspection and palpation involving thyroid glands

A

throat thickening (swallow), breathing, size, symmetrical, tender

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14
Q

which thyroid test is an accurate indicator of thyroid problems

A

T3 resin uptake

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15
Q

what measures rate of idoine

A

radioactive iodine uptake

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16
Q

what does a fine needle aspiration biopsy do?

A

look for cancer

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17
Q

patho of secondary hypothyroid

A

inc. TRH -> dec. TSH = dec. T3 T4

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18
Q

what are some meds that affect thyroid testing

A

-amiodarone
-aspirin
-cimetidine
-estrogens
-furosemide
-glucocorticoids
-heparin
-lithium
-phenytoin

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19
Q

what is deficiency of TH

A

hypothyroidism

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20
Q

characteristics of hypothyroidism

A

-slowed metabolism
-decreased heat production
-decreased oxygen consumption by tissues

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21
Q

what is primary hypothyroidism

A

-autoimmune thyroiditis (hashimoto)
-95% of cases
-involves actual gland

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22
Q

what is secondary hypothyroidism

A

-overtreatment of hyperthyroidism
-thyroidectomy (replace hormones)
-radioactive iodine
-something else causes it, not a gland problem

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23
Q

clinical manifestations / symptoms of hypothyroidism

A

-intolerance to cold
-dry skin
-hair loss
-anorexia
-lethargy
-muscle cramps/wekaness
-apathy
-facial/eyelid edema
-blank expression
-brittle nails and hair

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24
Q

what is a major problem from hypothyroidism

A

myxedema

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25
describe myxedema
-elevated cholesterol -life threatening and rare -undiagnosed/undertreated -can be exacerbated
26
what other complications come from myxedema?
-hyponatremia -hypercalcemia -hypoglycemia -water intoxication -hypoventilation
27
what are some symptoms of myxedema?
depression, diminished cognitive status, lethargy, and somnolence
28
which symptoms of myxedema are life threatening and require intensive support
-hyponatremia -hypoglycemia -hypoventilation -hypotension -bradycardia -hyponatremia -CV collapse -shock
29
pharmacologic therapy for hypothyroidism
levothyroxine (replacing TH, not TSH)
30
how do you manage hypothyroidism?
administer thyroid hormone
31
what are interventions for myxedema?
ventilation, control co2, maintain vs, not too much fluid
32
what do hypothyroidism meds effect and what kind if effects
-increase warfarin effectiveness -CV effects of adrenergic agents
33
what does graves disease (hyperthyroidism) have?
toxic, difffuse, goiter
34
three hallmarks of hyperthyroidism (graves)
goiter, hyperthyroidism, exopthalmos
35
average age of graves (hyperthyroidism)
-
36
hat antibodies are made in graves disease?
IgG antibodies
37
what is hyoerthyroidism
excess thyroid hormone (grave's)
38
what are common forms of hyperthyroidism
-toxic multinodular goiter -toxic adenoma -thyroiditis -grave's
39
clinical manifestations (signs) of hyperthyroidism
-intolerance to heat -oily skin -weight loss -bulging eyes -tachycardia -breast enlargement -inc. systolic -tremors -clubbing
40
complications of hyperthyroidism
-exopthalmos -heart disease -thyroid storm
41
what are other names for thyroid storm
thyroid crisis thyroid toxicosis
42
what is medical management for hyperthyroidism
-anti-thyroid meds -SSKI (lugols solution) -radioactive iodine -thyroidectomy
43
what are antithyroid meds?
PTU and methimazole (tapazole)
44
nursing interventions for hyperthyroidism
-maintain high calorie high protein -daily weight -maintain cardiac output
45
enlargement of the thyroid gland after swallowing/breathing
goiter
46
where do goiters come from
hypothyroidism or hyperthyroidism
47
are goiters malignant
could be either
48
types of goiters
-endemic (iodine deficient) -nodular
49
what are endemic goiters and where do they come from?
-iodine deficient -from hypothyroidism
50
what is a nodular goiter
-benign but can turn malignant -from hyperthyroidism
51
risk factors for thyroid tumors
-external radiation -smoking -sedentary -unhealthy eating -high stress
52
pre-op care fro thyroid cancer
CBC, anemia, calcium, thyroid level, what to expect, yankaur
53
post op care for thyroid cancer
-inc. HOB for edema, dont move head (sandbags), look for blood behind head, monitor complications
54
what is important to monitor after a thyroidectomy
calcium
55
how many parathyroid glands are there?
4, up to 12
56
what does PTH do
regulate calcium
57
secondary hyperparathyroidism causes _______
increased clacium in blood
58
over activity of one or more parathyroid glands
hyperparathyroidism
59
excess parathyroid hormone = ______
increased serum calcium
60
what can hyperparathyroidism lead to?
-inc. calcium (in blood) -bone decalcification (pulled from bone) -renal calculi
61
how old are hyperparathyroid patients
> 60
62
s/sx hyperparathyroidism
-anorexia -n/v -constipation -abd pain, bone pain -bone cysts -dysrhythmias -fatigue
63
what is a complication of hyperparathyroidism?
hypercalcemic crisis
64
what levels classify hypercalcemic crisis?
> 13 mg/dl
65
what do pts with hyperparathyroidism need
rapid rehydration (calcitonin)
66
medical management of hyperparathyroidism
-surgical removal (hypoparathyroidism) -hydration therapy -mobility -diet and meds
67
what meds are used in hyperparathyroidism
calcium chelators phosphates calcitonin
68
nursing care for hyperparathyroidism
monitor for stones VS strain urine limit fluids with calcium
69
what are causes of hypoparathyroidism
-iatrogenic (treatment-induced) -idiopathic (unknown)
70
s/sx of hypoparathyroidism
n/t cramps spasms seizures mental changes muscle contractions chvostek (facial) and trousseau (wrist/hand)
71
complications of hypoparathyroidism
-respiratory obstruction (spasms) -calcification of eyes/basal ganglia
72
hoe to diagnose hypoparathyroidism
EEG, labs (PTH), CT
73
in hypoparathyroidism, focus on correcting...
-hypocalcemia (replace magnesium) CALCIUM GLUCONATE! -vit. D deficiency -hypomagnesemia